Patents Examined by Robert Zeman
  • Translation initiation factor 4AIII and methods of use thereof
    Patent number: 6197947
    Abstract: The present invention provides a vertebrate translation initiation factor (eIF-4AIII), that plays a role in the differentiation of an embryonic cell to an epideimal cell. This translation initiation factor interacts with BMP-4 in a positive regulatory loop. The nucleic acid and amino acid sequences are also disclosed. Also disclosed are methods of using the translation initiation factor, nucleic acids encoding the same, and corresponding antibodies and the like.
    Type: Grant
    Filed: May 25, 1999
    Date of Patent: March 6, 2001
    Assignee: The Rockefeller University
    Inventors: Ali Hemmati-Brivanlou, Daniel C. Weinstein