Patents Examined by Robin Lynn Teskin
  • Vaccine utilizing an avirulent strain of Salmonella typhimurium
    Patent number: 4764370
    Abstract: A vaccine against a microbial pathogen comprised of a live, immunogenic but prototrophic and avirulent mutant strain of the selected microbial pathogen in an amount effective to confer immunity. A method of obtaining a vaccine that induces a heightened cellular and humoral immune response to one of a variety of microbial pathogens in a warm blooded animal. A method for isolation of an avirulent strain of a selected pathogenic microorganism.
    Type: Grant
    Filed: September 12, 1984
    Date of Patent: August 16, 1988
    Assignee: Scripps Clinic and Research Foundation
    Inventors: Patricia I. Fields, Constantine G. Haidaris, Frederick L. Heffron