Abstract: According to one of the aspects of an MRI apparatus of the present invention, the MRI apparatus includes an imaging data acquiring unit and a blood flow information generating unit. The imaging data acquiring unit acquires imaging data from an imaging region including myocardium, without using a contrast medium, by applying a spatial selective excitation pulse to a region including at least a part of an ascending aorta for distinguishably displaying inflowing blood flowing into the imaging region. The blood flow information generating unit generates blood flow image data based on the imaging data.

Abstract: Molecular imaging of radioluminescent nanoparticle probes injected into biological tissue is performed by irradiated the tissue with ionizing radiation to induce radioluminescence at optical wavelengths, preferably at predetermined near infrared wavelengths. The optical light is detected and processed to determine a spatial distribution of the probes. The radioluminescent nanoparticles may be inorganic or organic phosphors, scintillators, or quantum dots. Imaging systems realizing this technique include tomographic systems using an x-ray beam to sequentially irradiate selected regions, systems with a radioactive source producing the ionizing radiation from outside the tissue, such as with a beam, or inside the tissue, such as with an endoscope or injected radiopharmaceutical.

Abstract: An ultrasound diagnostic adapter used when diagnosing a subject using an ultrasound probe that transmits and receives ultrasound waves, the ultrasound diagnostic adapter includes: a pad which has (i) a main surface that is a surface on a side where the ultrasound probe is disposed, and (ii) a back surface that is a surface which is opposite to the main surface and is on a side where the subject is disposed; and a first reflective member which is disposed inside the pad and made from a material having a different acoustic impedance than a material included in the pad, wherein the first reflective member is disposed such that at least one of (i) a distance between the first reflective member and the main surface and (ii) a width of the first reflective member viewed from the side of the main surface varies depending on a position in the main surface.

Abstract: A system for imaging a biological sample including a tubular body having a side wall defining an interior shaped and sized for receiving the biological sample, an electromagnetic source positioned at one end of the tubular body interior for directing electromagnetic energy into the biological sample in the body interior, and an ultrasonic transducer positioned along said side wall of the body for receiving ultrasonic energy induced by the electromagnetic energy and transmitted through the biological sample.

Abstract: A method of controlling an output voltage of an ultrasound signal that is output by an ultrasound signal generating unit to a target object via a probe, the method including acquiring a target output voltage to be output by the probe to the target object and transmission conditions; acquiring property information regarding the probe; and controlling a voltage of the ultrasound signal output by the ultrasound signal generating unit based on the target output voltage, the transmission conditions, and the property information regarding the probe.

Abstract: A system and method for locating magnetic material. In one embodiment the system includes a magnetic probe; a power module in electrical communication with the magnetic probe to supply current to the magnetic probe; a sense module in electrical communication with the magnetic probe to receive signals from the magnetic probe; and a processing module in electrical communication with the power module and the sense module. The processing module generates a waveform that controls the supply of current from the power module and receives a signal from the sense module that indicates the presence of magnetic material. The magnetic probe is constructed from a material having a coefficient of thermal expansion of substantially 10?6/° C. or less and a Young's modulus of substantially 50 GPa or greater. In one embodiment magnetic nanoparticles collect in the lymph nodes. In one embodiment the particles have a mean hydrodynamic diameter of between 5-200 nm.

Abstract: A method for bolus tracking includes acquiring one or more baseline images. One or more trigger regions are automatically established within the baseline images. A bolus is administered. The automatically established trigger regions are monitored for bolus arrival at the one or more trigger regions. Bolus arrival at a volume of interest is forecasted based on the bolus arrival at the one or more trigger regions. A diagnostic scan of the volume of interest is acquired at the forecasted time.

Abstract: A system includes a transducer configured to emit ultrasound in response to receiving an electrical signal from a driving circuit. The transducer includes a first dimension that determines a frequency of the ultrasound and a second dimension that determines an impedance of the transducer. The frequency is independent of the second dimension.

Abstract: Provided are a three-dimensional (3D) ultrasound system and a method for operating the 3D ultrasound system. The 3D ultrasound system may include a display unit to form an image with respect to an object in the body and to display the image on a screen, and a control unit to generate a figure template corresponding to the image, to adjust the generated figure template based on a reference location of the image, and to superimpose the adjusted figure template on the image and display the resulting combination.

Abstract: Collisions between a minimally invasive surgical instrument and patient tissue are prevented in various ways. In one aspect a body cavity is mapped by recording positions of a surgical instrument, and the map is used to insert another surgical instrument. In another aspect, a surgical instrument is inserted into a space vacated by a guide tube. In yet another aspect, a volume is defined in which a control system permits an instrument to move, and the volume is a sum of one volume that is defined by previous movements of the instrument and other volume that is defined by the boundaries of an image capture component. In yet another aspect, a real time image of a surgical site is mosaiced over a previously recorded more distal image of the site. Surgical instruments are visible in the real time image, and representations of the surgical instruments as they would appear in the previously recorded image are generated and displayed on the previously recorded image.

Abstract: A method for evaluating flow characteristics in a vessel of a patient includes the steps of positioning a catheter having a balloon at a measuring location within the vessel; transmitting an ultrasound signal into the vessel while the balloon catheter is within the measuring location; evaluating a reflection of the ultrasound signal to determine a flow parameter within the vessel while the catheter is in the measuring position; expanding the balloon within the vessel at the measuring location; and stopping the expanding step when the result of the evaluating step is that the flow through the vessel is substantially stopped. In some embodiments, the method may further comprise the step of detecting an endovascular electrogram signal. The method may be designed for evaluating flow characteristics in a vessel of a patient while enabling the prevention of a balloon from over-expanding and/or over-distending a vessel of a patient.

Abstract: Changes in tissue stiffness have long been associated with disease. Systems and methods for determining the stiffness of tissues using ultrasonography may include a device for inducing a propagating shear wave in tissue and tracking the speed of propagation, which is directly related to tissue stiffness and density. The speed of a propagating shear wave may be detected by imaging a tissue at a high frame rate and detecting the propagating wave as a perturbance in successive image frames relative to a baseline image of the tissue in an undisturbed state. In some embodiments, sufficiently high frame rates may be achieved by using a ping-based ultrasound imaging technique in which unfocused omni-directional pings are transmitted (in an imaging plane or in a hemisphere) into a region of interest. Receiving echoes of the omnidirectional pings with multiple receive apertures allows for substantially improved lateral resolution.

Abstract: Apparatus and method can be provided for obtaining information regarding at least one portion of a biological structure. For example, using a first arrangement, it is possible to generate a first electro-magnetic radiation to be forwarded to the portion and receive, from the portion, a second fluorescent radiation associated with the first electro-magnetic radiation Further, using a second arrangement, it is possible to obtain information associated with the second fluorescent radiation, and generate at least one image of the portion as a function of the second fluorescent radiation. According to an exemplary embodiment of the present invention, the first arrangement can be inserted into at least one lumen, and the image of the portion may be associated with the at least one lumen.

Abstract: An isolation system with imaging or radiation therapy capability is disclosed. At least one containment barrier (14, 15, 16, 17) defines an isolation region (10). An imaging or therapy system (20) is disposed outside of the isolation region. The containment barrier includes a substantially hollow tubular extension (24, 42, 44, 124, 224, 324) protruding away from the isolation region (10). The substantially hollow tubular extension surrounds an interior volume (26) that is in fluid communication with the isolation region and is in fluid isolation from the imaging or therapy system. The substantially hollow tubular extension is made at least partially of a material providing operative communication between the imaging or therapy system and the interior volume of the substantially hollow tubular extension.

Abstract: Methods and systems for pulse scanning and simultaneously displaying a blood flow image and a B-mode image are disclosed.

Abstract: A PET-MRI apparatus includes a patient support assembly having a cradle to accommodate a subject, a carriage assembly to attach to the cradle and cause the cradle to selectively travel, and a rear bridge to receive the cradle and carriage. The patient support assembly also includes a front bridge to receive the cradle and carriage assembly and provide for translation therealong, with the front bridge including a first section and a second section that is spaced apart from the first section to form a gap in the front bridge between the first section and the second section in an area adjacent a PET detector array of the PET-MRI apparatus. The front and rear bridges include an anti-tip rail assembly to interact with the cradle and the carriage assembly so as to prevent tipping thereof when traversing over the gap between the first and second sections of the front bridge.

Abstract: A Multiple Aperture Ultrasound Imaging (MAUI) probe or transducer is uniquely capable of simultaneous imaging of a region of interest from separate apertures of ultrasound arrays. Some embodiments provide systems and methods for designing, building and using ultrasound probes having continuous arrays of ultrasound transducers which may have a substantially continuous concave curved shape in two or three dimensions (i.e. concave relative to an object to be imaged). Other embodiments herein provide systems and methods for designing, building and using ultrasound imaging probes having other unique configurations, such as adjustable probes and probes with variable configurations.

Abstract: An ultrasound imaging device and method for clutter filtering is provided. The ultrasound imaging device provides logic for calculating signal characteristic values from an in-phase/quadrature-phase (I/Q) of an ultrasound signal reflected from an object and determining to remove a clutter element from the I/Q signal through comparison of the calculated signal characteristic values. Accordingly, the ultrasound imaging device provides a blood flow distribution of the object, more precisely visualized, to a user.

Abstract: A system and method for tracking a tracking device for use with a surgical navigation system is provided. The system and method can include at least one tracking device having a plurality of faces. The faces can be operable to generate a signal upon activation. Also included is a face activation module that activates a selected one of the faces upon receipt of an activation signal. The system can also include a visibility module that generates the activation signal and receives the signal from the face to generate tracking data for the tracking device, along with a face switching module that generates a face control signal to activate a different face based on the tracking data.

Abstract: A method of tracking a position of a catheter within a patient includes securing a navigational reference at a reference location within the patient, defining the reference location as the origin of a coordinate system, determining a location of an electrode moving within the patient relative to that coordinate system, monitoring for a dislodgement of the navigational reference from the initial reference location, for example by measuring the navigational reference relative to a far field reference outside the patient's body, and generating a signal indicating that the navigational reference has dislodged from the reference location. Upon dislodgement, a user may be provided with guidance to help reposition and secure the navigational reference to the initial reference location, or the navigational reference may be automatically repositioned and secured to the initial reference location. Alternatively, a reference adjustment may be calculated to compensate for the changed reference point/origin.