Patents Examined by Roger Gobrogge
  • Patent number: 4942172
    Abstract: A method of curing or alleviating hepatic disease comprising administrating to the patient 1,3-dithiole-2-thione or 1,3-dithiolane-2-thione is disclosed. Adminstration of the compound can be made in various dosing forms, including tablets, granules, powders, capsules, suspensions, injections, and suppositories. Normal dosing amount can be determined from the range of 0.01 to 50 mg/kg/day for oral administration, and 0.002 to 10 mg/kg/day for injection or other forms of administration.
    Type: Grant
    Filed: May 20, 1988
    Date of Patent: July 17, 1990
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Hitoshi Nakazawa, Mari Ohtsuka, Hideaki Matsuda, Tatsuhiko Katori, Kazuhiko Irinoda
  • Patent number: 4877607
    Abstract: Certain cyclohexyl and cyclohexenyl aliphatic alcohols and ketones are potent attractants for Dacus latifrons, the Malaysian fruit fly. By attracting adult males to field traps, the compounds provide a means for detecting, monitoring, and controlling this agricultural pest.
    Type: Grant
    Filed: September 22, 1988
    Date of Patent: October 31, 1989
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Terrence P. McGovern, Robert A. Flath, Roy T. Cunningham
  • Patent number: 4873084
    Abstract: It was discovered that the chemical compositions, comprising ammoniumpentaborate and alkali metal and/or alkaline earth metal: sulfates, -sulfites and/or -hydrophosphates are excellent pesticides against wood decaying insects and fungi. The compositions of matter are also useful as fire retardants and anti-smoldering agents in textiles, wood materials and synthetic polymers.Mixtures of bariumtriborate and these barium salts (SO.sub.3, SO.sub.4, and/or HPO.sub.4) are useful as fire retardants in cellulose materials, paints, adhesives and synthetic polymers. The barium- and calcium-triborate compositions also act as pesticides and are useful in wood preservation against wood boring insects and wood decaying fungi.Ammoniumpentaborate (NH.sub.4.B.sub.5 O.sub.8.4 H.sub.2 O), ammoniumtetraborate [(NH.sub.4).sub.2.B.sub.4 O.sub.7.4 H.sub.2 O] and disodiumoctaborate (Na.sub.2 B.sub.8 O.sub.13.4 H.sub.
    Type: Grant
    Filed: December 18, 1987
    Date of Patent: October 10, 1989
    Inventor: Stephen I. Sallay
  • Patent number: 4866058
    Abstract: The present invention is directed to a method of controlling hyperlipidemia in mammals which comprises administering to a mammal an amount effective to control hyperlipidemia of a compound having hypolipidemic activity and the structural formula: ##STR1## wherein R.sup.1 is hydrogen, a C.sub.1 to C.sub.18 alkyl or substituted alkyl, a C.sub.2 to C.sub.18 alkenyl or substituted alkenyl, a C.sub.2 to C.sub.18 alkynyl or substituted alkynyl, a C.sub.4 to C.sub.10 cycloalkyl or substituted cycloalkyl, a C.sub.4 to C.sub.10 cycloalkenyl or substituted cycloalkenyl, phenyl, a substituted phenyl, cyano, phenalkyl, --CO--R.sup.9 or --Y--CO--R.sup.9 ;R.sup.2 is ##STR2## R.sup.3 and R.sup.4 can be the same or different and are each the same as R.sup.1 ;R.sup.5, R.sup.6 and R.sup.7 can be the same or different and are each hydrogen, a C.sub.1 to C.sub.18 alkyl or substituted alkyl, a C.sub.2 to C.sub.18 alkenyl or substituted alkenyl, a C.sub.1 to C.sub.18 alkynyl or substituted alkynyl, a C.sub.4 to C.sub.
    Type: Grant
    Filed: July 27, 1988
    Date of Patent: September 12, 1989
    Inventors: Robert A. Izydore, Iris H. Hall
  • Patent number: 4861795
    Abstract: Disclosed are pharmaceutical compositions containing naphthoic acid derivatives and method of use for enhancing oxygen availability to mammailian tissue.
    Type: Grant
    Filed: June 23, 1988
    Date of Patent: August 29, 1989
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: John T. Suh, Robert G. Pendelton, Charles E. Pendley, II, Kin T. Yu, Paul R. Menard, Alain B. Schreiber
  • Patent number: 4861585
    Abstract: A novel rodent edible is disclosed. The edible contains a conventional edible component, and an attractant naturally present in the breath of said rodents in an amount effective to increase the preference for said edible component to said rodents. Carbon disulfide and carbonyl sulfide are the preferred attractants. Preference for the edible component may be achieved by mixing the attractant with the food, or merely by associating the aroma of the attractant with the edible component to stimulate a preference for that component.
    Type: Grant
    Filed: September 22, 1988
    Date of Patent: August 29, 1989
    Assignee: Monell Chemical Senses Center
    Inventors: Bennett G. Galef, Jr., J. Russell Mason
  • Patent number: 4861794
    Abstract: This invention relates to the use of certain 3-substituted-2-oxindole-1-carboxamides of the formula ##STR1## and the pharmaceutically-acceptable base salts thereof wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl to inhibit interleukin-1 biosynthesis in a mammal. This invention also relates to the use of such compounds for treating interleukin-1 mediated disorders and dysfunctions such as bone and connective tissue metabolism disorders and immune dysfunction in a mammal. The methods of this invention comprise administering an interleukin-1 biosynthesis inhibiting amount of the compounds and salts of this invention to such a mammal.
    Type: Grant
    Filed: April 13, 1988
    Date of Patent: August 29, 1989
    Assignee: Pfizer Inc.
    Inventor: Ivan G. Otterness
  • Patent number: 4853413
    Abstract: Described are animal control compositions and methods; which compositions comprise citronellyl nitrile, citronellol and, optionally, methyl terpenyl ether, lemon oil, caryophyllene, isopulegol, isopulegyl acetate and quinine or one or more of its salts. The compositions can be used "as is" or in the form of a "controlled release" composition whereby the citronellyl nitrile, citronellol and, optionally, methyl terpenyl ether, lemon oil, caryophyllene, isopulegol, isopulegyl acetate and quinine or one or more of its salts are intimately admixed (alone or with adjuvants including but not limited to other volatile, odorous ingredients) with a polymeric substance such as polyethylene in the form of pellets or functional articles, e.g., garbage bags.
    Type: Grant
    Filed: April 3, 1987
    Date of Patent: August 1, 1989
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Ira Katz, Donald A. Withycombe
  • Patent number: 4853409
    Abstract: This invention relates to the use of certain 3-substituted-2-oxindole-1-carboxamides of the formula ##STR1## and the pharmaceutically-acceptable base salts thereof wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl to suppress T-cell function in a mammal. This invention also relates to the use of such compounds for treating T-cell mediated autoimmune disorders of the systemic or organ specific type. The methods of this invention comprise administering a T-cell function suppressing amount of the compounds and salts of this invention to such a mammal.
    Type: Grant
    Filed: April 13, 1988
    Date of Patent: August 1, 1989
    Assignee: Pfizer Inc.
    Inventor: Henry J. Showell
  • Patent number: 4851212
    Abstract: An air deodorizer, and a method for deodorizing rooms therewith, utilizing an aerosol of a solution containing from 2-25% by weight of non-toxic, non-oxidizing, deodorizing agent, said solution constituting liquid droplets having a weight average droplet size of less than 50 microns, more than 90% of said droplets having a size, by count, of less than 10 microns.
    Type: Grant
    Filed: December 23, 1987
    Date of Patent: July 25, 1989
    Assignee: Church & Dwight Co. Inc.
    Inventors: Anthony E. Winston, Raymond S. Brown, Frederick W. Lawson, Norman Usen
  • Patent number: 4851222
    Abstract: In a process for promoting regenerating of bone marrow there is administered to a mammal in need thereof an effective regeneration promoting dose of an aqueous solution of stabilized oxygen in a matrix of chlorite ions.
    Type: Grant
    Filed: January 27, 1988
    Date of Patent: July 25, 1989
    Assignee: Oxo Chemie GmbH
    Inventors: Friedrich W. Kuhne, Stanislav Ivankovic
  • Patent number: 4851403
    Abstract: The present invention relates to a method of potentiating radiation therapy using Co(III) complexes of water soluble, synthetic meso-substituted porphyrins. The method results in the sensitization of both well oxygenated (oxic) and oxygen deficient (hypoxic) tumor cells.
    Type: Grant
    Filed: April 21, 1987
    Date of Patent: July 25, 1989
    Assignee: Johnson Matthey, Inc.
    Inventors: Donald H. Picker, Michael J. Abrams, Jean F. Vollano, Christen M. Giandomenico
  • Patent number: 4849220
    Abstract: The oral administration of boron compounds such as sodium borate and boric acid increases the amounts of hydroxylated steroids in human plasma. This will help prevent or alleviate pathology, such as osteoporosis, caused by suboptimal circulating hydroxylated steroids such as 17.beta.-estradiol and testosterone.
    Type: Grant
    Filed: April 20, 1988
    Date of Patent: July 18, 1989
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Forrest H. Nielsen, Curtiss D. Hunt
  • Patent number: 4849216
    Abstract: A fly attractant composition includes a quantity of poultry protein wherein the poultry protein includes a quantity of at lesat one protein digestive microorganism capable of digesting the protein. This microorganism can either be native to the protein or it can be added as an inoculum. Further the composition contains a quantity of a carbohydrate which is capable of being fermented to yield carbon dioxide as a fermentation product. Additionally the composition contains a quantity of at least one carbohydrate fermentation microorganism which is capable of fermenting the carbohydrate to release carbon dioxide. When water is added to the fly attractant composition to form a fly lure, the carbon dioxide from the fermenting carbohydrate drives off odors from the ingredients which attracts flies to the lure.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: July 18, 1989
    Assignee: Wescotek, Inc.
    Inventor: David A. Andersen
  • Patent number: 4847292
    Abstract: Described are animal control compositions and methods; which compositions comprise citronellyl nitrile, citronellol alpha-terpinyl methyl ether and lemon oil and, optionally, caryophyllene, isopulegol, isopulegyl acetate, one or more norbornyl alkyl ethers, one or more 3,4,5,6,6-pentamethyl hexanol-2 derivatives and quinine or one or more of its salts. The compositions can be used "as is" or in the form of a "controlled release" composition whereby the citronellyl nitrile, citronellol, alpha-terpinyl methyl ether and lemon oil and, optionally, the caryophyllene, isopulegol, isopulegyl acetate, one or more norbornyl alkyl ethers, one or more 3,4,5,6,6-pentamethyl hexanol-2 derivatives and quinine or one or more of its salts are intimately admixed (alone or with adjuvants including but not limited to other volatile, odorous ingredients) with a polymeric substance such as polyethylene in the form of pellets or functional articles, e.g., garbage bags.
    Type: Grant
    Filed: June 29, 1987
    Date of Patent: July 11, 1989
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Ira Katz, Donald A. Withycombe, deceased, Marie R. Hanna
  • Patent number: 4845131
    Abstract: A method of combating clothes moths which comprises placing adjacent clothes to be protected from said moths or placing in a container for storing such clothes a clothes-moth-combatting effective amount of isoborneol of the formula ##STR1##
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: July 4, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Behrenz, Gianfranco Salvetti
  • Patent number: 4840798
    Abstract: The present invention provides a stable astringent gel composition containing pharmaceutically acceptable dosage levels of Burow's solution which remains stable over extended periods of storage and which can readily be applied to the skin to alleviate inflammatory conditions, erythema, chapping and minor skin irritations. The composition comprises a mixture of Burow's solution, a thickening or gelling agent, at least one glycol and polyglycol, dispersed in gypsum saturated purified water. The gel is adapted for application directly to affected areas of the skin to bind or tighten the soft tissue and also to tone and moisturize the skin.
    Type: Grant
    Filed: July 27, 1988
    Date of Patent: June 20, 1989
    Assignee: Theon, Inc.
    Inventor: Dennis A. Skaliotis
  • Patent number: 4828829
    Abstract: A visual fish attractant that visually attracts fish and aids in the dispersion of traditional scent and taste attractants is disclosed. The fish attractant compositions, if oil based, include one or more oils, such as mineral oil, cod liver oil, menhaden oil, herring oil, anise oil, salmon oil, as well as pigments, fragrances, fish scent, dispersed pigments, and light-reflective particles that act both as a visual attractant and as an aid to controlled dispersion of the oil and scent components.
    Type: Grant
    Filed: February 22, 1988
    Date of Patent: May 9, 1989
    Assignee: Flow-Rite of Tennessee, Inc.
    Inventor: William D. Bethshears