Patents Examined by Roger Gobrogge
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Patent number: 4942172Abstract: A method of curing or alleviating hepatic disease comprising administrating to the patient 1,3-dithiole-2-thione or 1,3-dithiolane-2-thione is disclosed. Adminstration of the compound can be made in various dosing forms, including tablets, granules, powders, capsules, suspensions, injections, and suppositories. Normal dosing amount can be determined from the range of 0.01 to 50 mg/kg/day for oral administration, and 0.002 to 10 mg/kg/day for injection or other forms of administration.Type: GrantFiled: May 20, 1988Date of Patent: July 17, 1990Assignee: SS Pharmaceutical Co., Ltd.Inventors: Hitoshi Nakazawa, Mari Ohtsuka, Hideaki Matsuda, Tatsuhiko Katori, Kazuhiko Irinoda
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Patent number: 4877607Abstract: Certain cyclohexyl and cyclohexenyl aliphatic alcohols and ketones are potent attractants for Dacus latifrons, the Malaysian fruit fly. By attracting adult males to field traps, the compounds provide a means for detecting, monitoring, and controlling this agricultural pest.Type: GrantFiled: September 22, 1988Date of Patent: October 31, 1989Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Terrence P. McGovern, Robert A. Flath, Roy T. Cunningham
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Patent number: 4873084Abstract: It was discovered that the chemical compositions, comprising ammoniumpentaborate and alkali metal and/or alkaline earth metal: sulfates, -sulfites and/or -hydrophosphates are excellent pesticides against wood decaying insects and fungi. The compositions of matter are also useful as fire retardants and anti-smoldering agents in textiles, wood materials and synthetic polymers.Mixtures of bariumtriborate and these barium salts (SO.sub.3, SO.sub.4, and/or HPO.sub.4) are useful as fire retardants in cellulose materials, paints, adhesives and synthetic polymers. The barium- and calcium-triborate compositions also act as pesticides and are useful in wood preservation against wood boring insects and wood decaying fungi.Ammoniumpentaborate (NH.sub.4.B.sub.5 O.sub.8.4 H.sub.2 O), ammoniumtetraborate [(NH.sub.4).sub.2.B.sub.4 O.sub.7.4 H.sub.2 O] and disodiumoctaborate (Na.sub.2 B.sub.8 O.sub.13.4 H.sub.Type: GrantFiled: December 18, 1987Date of Patent: October 10, 1989Inventor: Stephen I. Sallay
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Patent number: 4866058Abstract: The present invention is directed to a method of controlling hyperlipidemia in mammals which comprises administering to a mammal an amount effective to control hyperlipidemia of a compound having hypolipidemic activity and the structural formula: ##STR1## wherein R.sup.1 is hydrogen, a C.sub.1 to C.sub.18 alkyl or substituted alkyl, a C.sub.2 to C.sub.18 alkenyl or substituted alkenyl, a C.sub.2 to C.sub.18 alkynyl or substituted alkynyl, a C.sub.4 to C.sub.10 cycloalkyl or substituted cycloalkyl, a C.sub.4 to C.sub.10 cycloalkenyl or substituted cycloalkenyl, phenyl, a substituted phenyl, cyano, phenalkyl, --CO--R.sup.9 or --Y--CO--R.sup.9 ;R.sup.2 is ##STR2## R.sup.3 and R.sup.4 can be the same or different and are each the same as R.sup.1 ;R.sup.5, R.sup.6 and R.sup.7 can be the same or different and are each hydrogen, a C.sub.1 to C.sub.18 alkyl or substituted alkyl, a C.sub.2 to C.sub.18 alkenyl or substituted alkenyl, a C.sub.1 to C.sub.18 alkynyl or substituted alkynyl, a C.sub.4 to C.sub.Type: GrantFiled: July 27, 1988Date of Patent: September 12, 1989Inventors: Robert A. Izydore, Iris H. Hall
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Patent number: 4861795Abstract: Disclosed are pharmaceutical compositions containing naphthoic acid derivatives and method of use for enhancing oxygen availability to mammailian tissue.Type: GrantFiled: June 23, 1988Date of Patent: August 29, 1989Assignee: Rorer Pharmaceutical CorporationInventors: John T. Suh, Robert G. Pendelton, Charles E. Pendley, II, Kin T. Yu, Paul R. Menard, Alain B. Schreiber
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Patent number: 4861585Abstract: A novel rodent edible is disclosed. The edible contains a conventional edible component, and an attractant naturally present in the breath of said rodents in an amount effective to increase the preference for said edible component to said rodents. Carbon disulfide and carbonyl sulfide are the preferred attractants. Preference for the edible component may be achieved by mixing the attractant with the food, or merely by associating the aroma of the attractant with the edible component to stimulate a preference for that component.Type: GrantFiled: September 22, 1988Date of Patent: August 29, 1989Assignee: Monell Chemical Senses CenterInventors: Bennett G. Galef, Jr., J. Russell Mason
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Patent number: 4861794Abstract: This invention relates to the use of certain 3-substituted-2-oxindole-1-carboxamides of the formula ##STR1## and the pharmaceutically-acceptable base salts thereof wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl to inhibit interleukin-1 biosynthesis in a mammal. This invention also relates to the use of such compounds for treating interleukin-1 mediated disorders and dysfunctions such as bone and connective tissue metabolism disorders and immune dysfunction in a mammal. The methods of this invention comprise administering an interleukin-1 biosynthesis inhibiting amount of the compounds and salts of this invention to such a mammal.Type: GrantFiled: April 13, 1988Date of Patent: August 29, 1989Assignee: Pfizer Inc.Inventor: Ivan G. Otterness
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Patent number: 4853413Abstract: Described are animal control compositions and methods; which compositions comprise citronellyl nitrile, citronellol and, optionally, methyl terpenyl ether, lemon oil, caryophyllene, isopulegol, isopulegyl acetate and quinine or one or more of its salts. The compositions can be used "as is" or in the form of a "controlled release" composition whereby the citronellyl nitrile, citronellol and, optionally, methyl terpenyl ether, lemon oil, caryophyllene, isopulegol, isopulegyl acetate and quinine or one or more of its salts are intimately admixed (alone or with adjuvants including but not limited to other volatile, odorous ingredients) with a polymeric substance such as polyethylene in the form of pellets or functional articles, e.g., garbage bags.Type: GrantFiled: April 3, 1987Date of Patent: August 1, 1989Assignee: International Flavors & Fragrances Inc.Inventors: Ira Katz, Donald A. Withycombe
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Patent number: 4853409Abstract: This invention relates to the use of certain 3-substituted-2-oxindole-1-carboxamides of the formula ##STR1## and the pharmaceutically-acceptable base salts thereof wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl to suppress T-cell function in a mammal. This invention also relates to the use of such compounds for treating T-cell mediated autoimmune disorders of the systemic or organ specific type. The methods of this invention comprise administering a T-cell function suppressing amount of the compounds and salts of this invention to such a mammal.Type: GrantFiled: April 13, 1988Date of Patent: August 1, 1989Assignee: Pfizer Inc.Inventor: Henry J. Showell
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Patent number: 4851212Abstract: An air deodorizer, and a method for deodorizing rooms therewith, utilizing an aerosol of a solution containing from 2-25% by weight of non-toxic, non-oxidizing, deodorizing agent, said solution constituting liquid droplets having a weight average droplet size of less than 50 microns, more than 90% of said droplets having a size, by count, of less than 10 microns.Type: GrantFiled: December 23, 1987Date of Patent: July 25, 1989Assignee: Church & Dwight Co. Inc.Inventors: Anthony E. Winston, Raymond S. Brown, Frederick W. Lawson, Norman Usen
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Patent number: 4851222Abstract: In a process for promoting regenerating of bone marrow there is administered to a mammal in need thereof an effective regeneration promoting dose of an aqueous solution of stabilized oxygen in a matrix of chlorite ions.Type: GrantFiled: January 27, 1988Date of Patent: July 25, 1989Assignee: Oxo Chemie GmbHInventors: Friedrich W. Kuhne, Stanislav Ivankovic
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Patent number: 4851403Abstract: The present invention relates to a method of potentiating radiation therapy using Co(III) complexes of water soluble, synthetic meso-substituted porphyrins. The method results in the sensitization of both well oxygenated (oxic) and oxygen deficient (hypoxic) tumor cells.Type: GrantFiled: April 21, 1987Date of Patent: July 25, 1989Assignee: Johnson Matthey, Inc.Inventors: Donald H. Picker, Michael J. Abrams, Jean F. Vollano, Christen M. Giandomenico
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Patent number: 4849220Abstract: The oral administration of boron compounds such as sodium borate and boric acid increases the amounts of hydroxylated steroids in human plasma. This will help prevent or alleviate pathology, such as osteoporosis, caused by suboptimal circulating hydroxylated steroids such as 17.beta.-estradiol and testosterone.Type: GrantFiled: April 20, 1988Date of Patent: July 18, 1989Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Forrest H. Nielsen, Curtiss D. Hunt
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Patent number: 4849216Abstract: A fly attractant composition includes a quantity of poultry protein wherein the poultry protein includes a quantity of at lesat one protein digestive microorganism capable of digesting the protein. This microorganism can either be native to the protein or it can be added as an inoculum. Further the composition contains a quantity of a carbohydrate which is capable of being fermented to yield carbon dioxide as a fermentation product. Additionally the composition contains a quantity of at least one carbohydrate fermentation microorganism which is capable of fermenting the carbohydrate to release carbon dioxide. When water is added to the fly attractant composition to form a fly lure, the carbon dioxide from the fermenting carbohydrate drives off odors from the ingredients which attracts flies to the lure.Type: GrantFiled: December 24, 1986Date of Patent: July 18, 1989Assignee: Wescotek, Inc.Inventor: David A. Andersen
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Patent number: 4847292Abstract: Described are animal control compositions and methods; which compositions comprise citronellyl nitrile, citronellol alpha-terpinyl methyl ether and lemon oil and, optionally, caryophyllene, isopulegol, isopulegyl acetate, one or more norbornyl alkyl ethers, one or more 3,4,5,6,6-pentamethyl hexanol-2 derivatives and quinine or one or more of its salts. The compositions can be used "as is" or in the form of a "controlled release" composition whereby the citronellyl nitrile, citronellol, alpha-terpinyl methyl ether and lemon oil and, optionally, the caryophyllene, isopulegol, isopulegyl acetate, one or more norbornyl alkyl ethers, one or more 3,4,5,6,6-pentamethyl hexanol-2 derivatives and quinine or one or more of its salts are intimately admixed (alone or with adjuvants including but not limited to other volatile, odorous ingredients) with a polymeric substance such as polyethylene in the form of pellets or functional articles, e.g., garbage bags.Type: GrantFiled: June 29, 1987Date of Patent: July 11, 1989Assignee: International Flavors & Fragrances Inc.Inventors: Ira Katz, Donald A. Withycombe, deceased, Marie R. Hanna
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Patent number: 4845131Abstract: A method of combating clothes moths which comprises placing adjacent clothes to be protected from said moths or placing in a container for storing such clothes a clothes-moth-combatting effective amount of isoborneol of the formula ##STR1##Type: GrantFiled: March 18, 1988Date of Patent: July 4, 1989Assignee: Bayer AktiengesellschaftInventors: Wolfgang Behrenz, Gianfranco Salvetti
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Patent number: 4840798Abstract: The present invention provides a stable astringent gel composition containing pharmaceutically acceptable dosage levels of Burow's solution which remains stable over extended periods of storage and which can readily be applied to the skin to alleviate inflammatory conditions, erythema, chapping and minor skin irritations. The composition comprises a mixture of Burow's solution, a thickening or gelling agent, at least one glycol and polyglycol, dispersed in gypsum saturated purified water. The gel is adapted for application directly to affected areas of the skin to bind or tighten the soft tissue and also to tone and moisturize the skin.Type: GrantFiled: July 27, 1988Date of Patent: June 20, 1989Assignee: Theon, Inc.Inventor: Dennis A. Skaliotis
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Patent number: 4828829Abstract: A visual fish attractant that visually attracts fish and aids in the dispersion of traditional scent and taste attractants is disclosed. The fish attractant compositions, if oil based, include one or more oils, such as mineral oil, cod liver oil, menhaden oil, herring oil, anise oil, salmon oil, as well as pigments, fragrances, fish scent, dispersed pigments, and light-reflective particles that act both as a visual attractant and as an aid to controlled dispersion of the oil and scent components.Type: GrantFiled: February 22, 1988Date of Patent: May 9, 1989Assignee: Flow-Rite of Tennessee, Inc.Inventor: William D. Bethshears