Patents Examined by Rokhaya Diop
  • Patent number: 10993802
    Abstract: A biocompatible and biodegradable construct having a base expandable member and an integral, internal support structure. The support structure is preferably formed from poly(glycerol sebacate) (PGS) or a magnesium alloy. The base member is preferably formed from acellular extracellular matrix (ECM) derived from small intestine submucosa (SIS) tissue that exhibits a flexible, porous, sponge-like structure adapted to expand upon absorption of a bodily fluid, wherein the construct seals a perivalvular leak when disposed proximate thereto.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: May 4, 2021
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: 10980627
    Abstract: A device for the treatment of esophageal stenoses, including at least a body of elongated shape intended to be inserted within the esophagus of a patient, and a tubular sheath mounted around said body to define an interspace between said body and the tubular sheath, wherein it includes a stiffening element accommodated in said interspace and including a plurality of ribs which extend along said interspace.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: April 20, 2021
    Assignees: Sidam S.r.l., Ospedale Pediatrico Bambino Gesu', Evoluzione S.r.l.
    Inventor: Luigi Dall'Oglio
  • Patent number: 10980917
    Abstract: A stent, the stent including a first coating composition disposed on at least a portion of the outer surface of the stent, the first coating composition having at least one bioadhesive and a second coating composition disposed over the first coating composition, the second coating composition having at least one biodegradable polymer, and methods of making and using the same.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: April 20, 2021
    Inventors: John Hingston, Gary Jordan, William Bertolino, Paul K. Norton, Jason Weiner
  • Patent number: 10973622
    Abstract: A reconstruction system and associated techniques for soft tissue repairs and repair augmentation. The reconstruction system is an internal soft tissue brace formed of at least one fixation device (for example, anchors or screws) and a replacement/reinforcement construct (for example, a suture construct in the form of a suture tape such as FiberTape® or a collagen tape or a suture with biological material or a collagen coated material, or a collagen patch, or a biological construct such as Arthroflex). The reinforcement construct and fixation devices may be used as a suture repair alone (to replace the ligament or tendon), or in conjunction with other traditional soft tissue repair procedures, acting as a reinforcement system for the repaired soft tissue.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: April 13, 2021
    Assignee: ARTHREX, INC.
    Inventor: Gordon M. Mackay
  • Patent number: 10966820
    Abstract: Described embodiments are directed toward prosthetic valves having leaflets of particular shapes that control bending character. In accordance with an embodiment, a prosthetic valve has a plurality of leaflets. Each leaflet includes a central region and two side regions on opposite sides of the central region. The central region is defined by a shape of an isosceles triangle defined by two central region sides, the leaflet base and the leaflet free edge, wherein the two central region sides converge from the leaflet base. Each of the two side regions has a shape of a triangle and each is defined by one of the central region sides, one of the leaflet sides, and the leaflet free edge.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 6, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: William C. Bruchman, Cody L. Hartman
  • Patent number: 10945831
    Abstract: A dermal tissue allograft includes a dermal matrix having a profile including first and second vertices, a first imaginary axis extending between the first and second vertices, a first peripheral edge extending along a continuous path from the first vertex to the second vertex on a first side of the first imaginary axis, and a second peripheral edge extending along a continuous path from the first vertex to the second vertex on a second side of the first imaginary axis. The first peripheral edge includes an apogee, a convex portion, and a concave portion. The convex and concave portions meet at a transition point located on the first peripheral edge between its apogee and the second vertex. The second peripheral edge includes an apogee and is convex. The second perpendicular distance is greater than the first perpendicular distance. The dermal matrix has a substantially uniform thickness across its profile.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: March 16, 2021
    Assignees: Musculoskeletal Transplant Foundation, The Methodist Hospital
    Inventors: Antonio M. Bunce, Todd J. Nilsen, Evangelia Chnari, Aldona J. Spiegel, Michael Locarno, Gregory P. Adams
  • Patent number: 10939992
    Abstract: Apparatus for reconstructing a ligament, the apparatus comprising a fixation device for maintaining a graft ligament in a bone hole, the fixation device comprising a fixation screw comprising a body having screw threads formed thereon; and a ligament spacer mounted to the fixation screw, the ligament spacer comprising a canted face disposed opposite the fixation screw; such that the fixation screw and ligament spacer may be advanced into the bone hole with the graft ligament so that the fixation screw and the ligament spacer maintain the graft ligament within the bone hole and the canted face of the ligament spacer is aligned with the adjacent surface of the bone.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: March 9, 2021
    Assignee: AnatomACL, LLC
    Inventor: Kelly G. Ammann
  • Patent number: 10932907
    Abstract: An annuloplasty ring for attachment to an annulus of a tricuspid valve comprises an elongate tube of suturable material comprising a central segment and first and second end segments. An arcuate stiff ener is received in the central segment of the tube and extends the length thereof. The arcuate stiffener is circumferentially confined within the central segment to prevent circumferential movement of the stiffener relative to the tube. The first and second end segments of the tube lack a stiffener and are axially deformable.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: March 2, 2021
    Assignee: Medtronic, Inc.
    Inventors: David H. Adams, John T. M. Wright
  • Patent number: 10902523
    Abstract: Methods and systems are provided for transplantation of a biological material to a plurality of recipients from a plurality of donors. One or a series of paired donations are made, where one or more donors and/or recipients can be international in origin. Improved care and cost savings are obtained by shifting time-based burdens; i.e., dialysis versus transplantation. Additional transplants, including transplants involving international participants, results in the improvement of local and global healthcare.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: January 26, 2021
    Inventor: Michael A. Rees
  • Patent number: 10898312
    Abstract: Fenestrated tissue grafts and acellular dermal matrices (ADMs) for use, for example, in breast reconstruction, are disclosed herein. In various embodiments, the improved tissue grafts are used in two-stage tissue expander breast reconstruction. Disclosed embodiments include altered ADMs and other tissue grafts, which comprise strategically placed fenestrations, and methods of making the same. The addition of specific patterns of fenestrations in the graft improve the breast reconstructive experience by increasing intra-operative fill volume and decreasing time to full expansion; such alterations to the graft may also increase cosmetic outcomes and patient comfort. In some embodiments, particular lengths, shapes, and measurements of overlap are used in the fenestration pattern.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: January 26, 2021
    Assignee: The Regents of the University of California
    Inventors: Garrett A. Wirth, Keyianoosh Z. Paydar, Patrick Guidotti, Donald S. Mowlds
  • Patent number: 10881502
    Abstract: A nipple implant assembly and method for implanting the nipple implant are provided. The nipple implant assembly includes a nipple skeleton with or without areola made of metallic or non-metallic memory-shape bio-compatible material. The nipple implant assembly may consist of holes to allow growth of natural breast tissue into the implant for improved holding better attachment of the implant into the human's tissue. The nipple implant assembly may be coated by or cast in a polymeric coating.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: January 5, 2021
    Assignee: FIXNIP LTD.
    Inventors: Yagil Netta Chaim, Daniel Korkos, Gil Ofir
  • Patent number: 10881499
    Abstract: Techniques and reconstruction systems for ligament repair and fixation. A bone tendon graft is prepared by folding the bone block over a suspensory fixation device (for example, a knotless suture construct such as a knotless, adjustable, self-cinching suture loop/button construct, a suture, crosspin, or screw, etc.). A flexible strand is then used to suture the bone plug to the tendon so that the overall graft is shortened significantly and the suspensory fixation device is securely attached. The technique does not require passage of the suspensory fixation device through the bone block which makes the graft passage easier since the graft is pulled from the tip. The technique also allows shortening of the overall graft.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: January 5, 2021
    Assignee: ARTHREX, INC.
    Inventor: Laura A. Timmerman
  • Patent number: 10631990
    Abstract: Implant apparatus and methods are directed toward treating conditions involving the knee joint, and the patella specifically, maintain alignment or address misalignment of a patella through a full range of motion of the knee joint Exemplary devices include an elastomeric, Y-shaped device which is secured to the femur and patella on opposite ends thereof by bone anchors. The elastomeric device can be either rotatably or non-rotatably connected to the bone anchors.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: April 28, 2020
    Assignee: MOXIMED, INC.
    Inventors: Anton G. Clifford, Josef L. Friedmann, Michael E. Landry, David Lowe, Mary O'Connell, Heber Saravia
  • Patent number: 10631975
    Abstract: An implant includes a hollow biocompatible shell, first and second electrodes, filling material, and circuitry. The hollow biocompatible shell is configured to be implanted in an organ of a patient. The first electrode is disposed inside the shell. The second electrode has at least one surface disposed outside the shell. The filling material, which includes carbon nanotubes (CNT), fills the shell and is configured, in response to a rupture occurring in the shell, to change a spatial orientation of the CNT and thus to cause a change in electrical conductivity of the filling material between the first electrode and the rupture. The circuitry is electrically connected to the first and second electrodes and is configured to detect the rupture by sensing the change in the electrical conductivity of the CNT, and to produce an output indicative of the detected rupture.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: April 28, 2020
    Inventors: Assaf Govari, Christopher Thomas Beeckler, Yehuda Algawi, Yaron Ephrath
  • Patent number: 10252025
    Abstract: A urinary prosthesis can include an elongate tube that can extend from outside a patient's body, through the patient's urethra, and into the patient's bladder. A funnel can be coupled to a terminal end portion of the elongate tube, and can be positioned inside the patient's bladder so that a surface of the funnel contacts tissue within the patient's bladder surrounding the patient's urethra across a full 360┬░ contact profile.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: April 9, 2019
    Inventor: Justin Garcia
  • Patent number: 10239262
    Abstract: A synthetic organ suitable for transplantation into a biological organism is provided. This synthetic organ includes a three-dimensional polymer scaffold, wherein the shape and dimensions of the polymer scaffold are based on a native organ, wherein the polymer scaffold further includes at least one layer of polymer fibers that have been deposited by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both; and wherein the polymer scaffold has been preseeded with at least one type of biological cell prior to implantation into a biological organism, and wherein the at least one type of biological cell is operative to facilitate integration of the polymer scaffold into the organism so that the polymer scaffold may function in a manner significantly similar to or the same as the native organ.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: March 26, 2019
    Inventor: Jed K. Johnson
  • Patent number: 10213296
    Abstract: A graft for augmentation rhinoplasty, the graft including bone tissue and cartilage tissue, and a method of performing augmentation rhinoplasty by using the graft are disclosed. According to the disclosure, autologous tissue for augmentation rhinoplasty can be obtained in a sufficient amount to so that a nose can be uplifted to a desired height. In addition, rhinoplasy can be easily performed, resulting in a naturally-shaped nose. As the osseous tissue is grafted on the originally existing osseous tissue and cartilage tissue is grafted on the originally existing cartilage, the construction of the original anatomical structure of the nose can be allowed and there is an effect that there is no side effect such as a foreign body reaction.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: February 26, 2019
    Inventor: Min Bo Shim
  • Patent number: 10188508
    Abstract: An engineered vocal fold mucosa, including an engineered lamina propria layer and an engineered squamous epithelium layer, is disclosed. The engineered lamina propria is made by seeding and culturing human vocal fold fibroblasts within a polymerized collagen scaffold, and the engineered squamous epithelium is made by culturing human vocal fold epithelial cells on the scaffold surface. The resulting engineered vocal fold mucosa is not immunogenic, and is capable of exhibiting the vibratory function and acoustic output of a native vocal fold mucosa. Accordingly, the engineered vocal fold mucosa may be implanted into the larynx to treat voice impairment.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: January 29, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Nathan Welham, Changying Ling
  • Patent number: 10182903
    Abstract: Systems and methods for preparing a ligament graft construct for a ligament reconstruction or repair procedure are provided. In general, the described techniques utilize a reinforcement material having at least one suture tail extending therefrom. The reinforcement material is a ribbon or a ribbon-like flattened portion attached to or integrally formed with the at least one suture tail. To prepare a tissue repair construct, the reinforcement material is positioned on a first surface of a graft to extend from an end thereof and the at least one suture tail, coupled to a needle, is repeatedly passed through the reinforcement material and the surface of the graft to a second surface of the graft, and around a side portion of the graft to thereby create multiple suture loops. The tissue repair construct can be formed on each end of the graft.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: January 22, 2019
    Assignee: DEPUY MITEK, LLC
    Inventor: Mehmet Z. Sengun
  • Patent number: 10172627
    Abstract: Embodiments of the invention include a system and method for coupling a graft to a bone. A graft preparation tool may be used to place one or more holes in a graft and an offset measurement tool may be used to determine the distance of the one or more holes from an edge of the graft to be aligned with a portion of the bone. One or more complementary holes may then be created in the bone and fasteners applied through the holes to couple the graft to the bone.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: January 8, 2019
    Assignee: Smith & Nephew, Inc.
    Inventors: Daniel Haberman, Stephen A. Santangelo, Nikhil N. Verma