Abstract: Methods, systems, and compositions are provided for implanting an implantable device into a biological tissue (e.g., muscle, brain). A subject implantable device includes: (i) a biocompatible substrate, (ii) a conduit (e.g., an electrode, a waveguide) that is disposed on the biocompatible substrate, and (iii) an engagement feature (e.g., a loop) for reversible engagement with an insertion needle. The biocompatible substrate can be flexible (e.g., can include polyimide). The implantable device is implanted using an insertion needle that includes an engagement feature corresponding to the engagement feature of the implantable device. To implant, an implantable device is reversibly engaged with an insertion needle, the device-loaded insertion needle is inserted into a biological tissue (e.g., to a desired depth), and the insertion needle is retracted, thereby disengaging the implantable device from the insertion needle and allowing the implantable device to remain implanted in the biological tissue.

Abstract: A system including a catheter navigable to a location within a patient, a lumen extending through the catheter and ending at the distal end in an orifice, a fluid controller in fluid communication with the lumen of the catheter and capable of supplying a fluid to or removing a fluid from an area proximate the desired location. The control of the fluid in the area proximate the desired location affecting a dielectric constant of the area proximate the desired location. The system includes a microwave energy source, and a microwave ablation probe connected to the microwave energy source, the microwave ablation probe being navigable to a desired location within the patient. Application of energy from the microwave energy source to the microwave ablation probe in an area proximate the desired location having the affected dielectric constant results in a substantially spherical tissue effect in the area proximate the desired location.

Abstract: Systems and methods for facilitating assessment and convenient display of graphical output indicative of lesion formation and outputting data indicative of lesion formation to a 3D mapping system to display on a 3D model are disclosed herein.

Abstract: An electrocautery unit for connecting to a handle of an electrocautery device, the unit comprises a body, a light unit and an electrode. The body has a body proximal end and a body distal end, and a body axis extending lengthwise along the center of the body. The body's proximal end comprises a connecting element for connecting said body to a handle having a handle axis extending lengthwise along the center of the handle, so that said body axis is coaxial with said handle axis when said body is connected to said handle. The light unit may be constructed and arranged to emit a light having a central axis coaxial with said body axis. The electrode comprises a proximate end connected to the body distal end, and an electrode tip at a distal said. When the electrode is connected to the body, the electrode lays outside of the body axis and extends into said body axis such that the electrode tip is within said body axis, wherein said light and said electrode tip are coaxial to said body axis and said handle axis.

Abstract: Devices, systems, and methods relating to a low-voltage, pre-treatment pulse routine for evaluating a potential for non-target tissue damage from the delivery of energy, such as electroporation energy to an area of target tissue. In one embodiment, a medical system includes a medical device having a treatment element; and a control unit in communication with the medical device, the control unit being configured to: deliver a low-voltage, pre-treatment pulse routine through the treatment element to an area of target tissue; determine whether the low-voltage, pre-treatment pulse routine has a stimulation effect on an area of non-target tissue; and deliver an ablation energy routine through the treatment element to the area of target tissue when the control unit determines that the low-voltage, pre-treatment pulse routine does not have a stimulation effect on the area of non-target tissue.

Abstract: A surgical instrument includes a shaft and a probe that extends distally from a distal end of the shaft. The probe includes a distal tip configured to puncture a tissue surface to enter a nerve canal of a patient, and an ablation element operable to ablate a nerve located within the nerve canal. The surgical instrument further includes a stop element arranged proximally of the distal tip. The stop element is configured to abut the tissue surface punctured by the distal tip. In some examples, the ablation element may be in the form of an RF electrode operable to ablate the nerve with RF energy. The surgical instrument may further include a navigation sensor operable to generate a signal corresponding to a location of the probe within the patient.

Abstract: Ablation systems and methods detect and address distortion caused by a variety of factors. A method includes measuring a temperature curve at target tissue; applying ablation energy to the target tissue; determining a peak temperature on the temperature curve; if the peak temperature is greater than the predetermined peak temperature, determining a time at which the temperature curve crosses to a lower temperature; and if the determined time is greater than a predetermined time, generating a message indicating that the target tissue was successfully ablated. Another method includes determining a distance between a remote temperature probe and an ablation probe, applying ablation energy to target tissue, measuring temperature at the remote temperature probe, estimating ablation size based on the determined distance and the temperature measured by the remote temperature probe, and determining whether the target tissue is successfully ablated based on the estimated ablation size.

Abstract: An electrosurgical generator and associated methods determine a real part of the impedance of treated tissue. The electrosurgical generator includes an output stage, a plurality of sensors, and a controller that controls the output stage. The controller includes a signal processor that determines an RMS voltage, an RMS current, an average power, and a real part of the impedance of the treated tissue based on measured voltage and current by using a plurality of averaging filters. The controller controls the output stage to generate electrosurgical energy based on at least the determined real part of the impedance.

Abstract: A biopotential can be measured with high accuracy without the electrodes coming into direct contact with the skin and without being affected by any motion artifact. The present invention comprises a first lead which detects a biopotential containing noise components, a second lead which is electrically isolated from the first lead and detects noise components, and a differential amplifier circuit which is input with a first signal output from the first lead and a second signal output from the second lead, and which amplifies and outputs a difference between the first signal and the second signal, wherein a value of an input impedance on the second signal side of the differential amplifier circuit is set so that the noise components detected from the second lead will have a frequency that is higher than a frequency spectrum of the biopotential.

Abstract: A surgical system includes an end effector assembly having first and second jaw members, a generator, and one or more machine learning applications. The first and/or second jaw member is movable relative to the other from a spaced-apart position to an approximated position for grasping tissue therebetween. The jaw members are configured to conduct energy therebetween and through tissue grasped therebetween. The generator includes an energy output configured to supply energy to the jaw members, a main controller configured to control the energy output, and sensor circuitry configured to sense impedance and/or power. The machine learning application(s) is configured to determine a type of tissue grasped between the first and second jaw members based upon the impedance and/or power sensed by the sensor circuitry.

Abstract: A system and method are presented for treating targeted tissue using cryoablation. An introducer canula and a cryoprobe are inserted the targeted tissue. The cryoprobe is cooled and an ice ball is formed. The cryoprobe is removed while the ice ball is still frozen, and an ultrasound catheter is inserted. Ultrasound generated within the ice ball is used to determine the distance from the ultrasound catheter to a perimeter of the ice ball. This is repeated at different angles to model a slice of the ice ball. The ultrasound catheter is moved radially, and the process is repeated to create a model of at least a portion of the ice ball. The ice ball model can be displayed on a registered set of images representing the targeted tissue to ensure that the tissue lies within the treatment zone of the ice ball.

Abstract: A surgical forceps includes a housing having a movable handle coupled thereto and movable between an initial position and a compressed position. A drive bar is operably coupled to the movable handle such that movement of the movable handle between the initial and compressed positions effects longitudinal translation of the drive bar. The drive bar further includes a coupling member disposed at a distal end thereof. An end effector assembly includes first and second jaw members movable between spaced-apart and approximated positions. Each jaw member defines a cam slot. A cam pin is slidably disposed within the cam slot of each of the jaw members. The coupling member is configured to releasably engage the cam pin such that movement of the movable handle between the initial position and the compressed position effects movement of the jaw members between the spaced-apart position and the approximated position.

Abstract: An ultrasonic motion generator includes a non-resonant inverter, an ultrasonic transducer, and a comparator. The non-resonant inverter inverts direct current (DC) to alternating current (AC) having a first frequency. The ultrasonic transducer is electrically coupled with the non-resonant inverter and generates an ultrasonic motion based on the inverted AC. The comparator automatically detects a deviation of the first frequency from a resonant frequency of the ultrasonic transducer based on motion current passing through the ultrasonic transducer and generates an output signal based on the deviation to drive the non-resonant inverter.

Abstract: Systems and methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Lifting sagging tissue on a face, neck, and/or body are described. Treatment with heat is provided in several embodiments.

Abstract: A method and apparatus for treating tissue are disclosed, including intra-operative mapping of a probe ablation zone. The method uses a system that maps the proximal and distal margins of the probe ablation zone using tools that access the ablation target. In some embodiments, the tools comprise a bone drill, and an introducer assembly, including a cannula and a stylet. The tools have features or markings that cooperate to indicate which probe to use to achieve the desired ablation. The method further facilitates planning probe placement for delivering energy to treat (ablate) a desired ablation volume of a target tissue by using a system that maps both the target tissue and possible probe ablation zones.

Abstract: According to some embodiments, a medical instrument comprises an elongate body having a proximal end and a distal end and a pair of electrodes or electrode portions (for example, a split-tip electrode assembly). Systems and methods are described herein that perform contact sensing and/or ablation confirmation based on electrical measurements obtained while energy of different frequencies are applied to the pair of electrodes or electrode portions. The contact sensing systems and methods may calibrate network parameter measurements to compensate for a hardware unit in a network parameter measurement circuit or to account for differences in cables, instrumentation or hardware used.

Abstract: Provided is a method for managing radio frequency (RF) and ultrasonic signals output by a generator that includes a surgical instrument comprising an RF energy output and an ultrasonic energy output and a circuit configured to receive a combined RF and ultrasonic signal from the generator. The method includes receiving a combined radio frequency (RF) and ultrasonic signal from a generator, generating a RF filtered signal by filtering RF frequency content from the combined signal; filtering ultrasonic frequency content from the combined signal; generating an ultrasonic filtered signal; providing the RF filtered signal to the RF energy output; and providing the ultrasonic filtered signal to the ultrasonic energy output.

Abstract: The disclosure notably relates to a system for phrenic nerve stimulation. The stimulation system comprises a catheter including one or more intravascular electrodes each arranged on a distal portion of the catheter. The catheter is configured to be introduced in the superior vena cava of a human patient. The stimulation system also comprises an extracorporeal electrode patch configured to be affixed to the patient opposite to the distal portion relative to the phrenic nerve. The extracorporeal electrode patch is operable in a bipolar mode with the one or more intravascular electrodes. Such a system forms an improved solution for phrenic nerve stimulation, in particular during a cryoablation procedure.

Abstract: A microwave ablation system and method include an elongate microwave ablation probe. The probe has a radiating portion for performing microwave ablation. The probe includes a first electrode and a second electrode located along the probe body. A radiofrequency energy source is connected to the first and second electrodes. An impedance of tissue is measured using the first and second electrodes. The impedance is used to detect a change in tissue due to microwave ablation of the tissue. Therapy parameters for the microwave ablation procedure can be adjusted in response to the measured impedance. In some examples, one of the electrodes is proximal and one electrode is distal to the radiating portion.

Abstract: System and methods of an electrosurgical controller having multiple modes of operation that are configured for treatment of a specific targeted tissue type and the electrosurgical effect desired where the treatment and effect are provided by a single controller and an electrosurgical probe. The electrosurgical controller includes an integrated fluid control apparatus or pump where activation of the controller allows for selective energy delivery and corresponding fluid volume flow rates. The electrosurgical probe includes a fluid transport lumen and is in communication with the controller and the pump for operation of the probe in the various user selected modes with accompanying energy delivery and fluid control directed to the desired treatment and surgical effect.