Abstract: The present invention provides a method and apparatus for delivering and controlling thermal therapy to a volume of diseased tissue. Specifically, the invention includes using thermal imaging and other inputs to determine an acoustic (ultrasonic) treatment regime employing interstitial ultrasound applicators to deliver a required therapeutic temperature or thermal dose to the affected region in a body or organ. Various aspects of the treatment that can be controlled include individual transducer element operating power and frequency, as well as the rate of cooling and rotation of the entire applicator.

Abstract: A hypothermia treatment sack comprising a top sheet and a bottom sheet releasably connecting along their perimeters to form a patient receiving cavity between the top and bottom sheets while allowing for patient access from any location around the perimeter. The top and bottom sheets include a weatherproof exterior side for repelling wind and water, and a heat reflective interior side for preventing heat from escaping. A plurality of self-activating heating pads are carried in the top sheet for producing heat when exposed to air. The heating pads have a first side exposed on the weatherproof exterior side of the top sheet to provide for a generally unrestricted airflow to the heating pads, and a second side exposed on the heat reflective interior side of the top sheet for radiating heat directly into the patient receiving cavity.

Abstract: An applicator and method for application of electromagnetic energy to an area of tissue is described. The applicator includes a visually-transparent, high-dielectric interfacing assembly which has a conformable tissue-engaging surface and an opposed antenna-engaging surface. At least one balanced, circularly-polarized antenna is disposed in a plane substantially parallel and adjacent to the antenna-engaging surface. The interfacing assembly and at least one antenna are substantially transparent to enable visual viewing of the area of tissue. This enables monitoring of the tissue for adverse treatment effects while electromagnetic energy is being applied to the at least one antenna and radiated into the tissue.

Abstract: A device and method for providing body cooling for treating fever. The cooling device applies cooling to blood flowing in a vein or artery, e.g., the vena cavae, that is then distributed throughout the body.

Abstract: Medical catheter apparatus for minimally invasive applications includes a probe for radiating electromagnetic waves of a first frequency capable of heating tissue and detecting thermal emissions from that tissue of a second frequency indicative of tissue temperature. The probe has an inner conductor extending along the probe to a conductive probe tip and a concentric tubular outer conductor having a leading end spaced rearwardly from the probe tip and a closed trailing end shorted to the inner conductor. A dielectric sheath surrounds the outer conductor which sheath has a leading end spaced rearwardly from the leading end of the outer conductor. A diplexer integrated into the probe includes a filter circuit positioned inside the outer conductor and a coupling capacitor connected between a point on the inner conductor and the input of the filter circuit such that the conductors between that point and the shorted trailing end of the outer conductor constitute a quarter wave stub at the second frequency.

Abstract: A robotic surgery system comprises a mounting base, a plurality of surgical instruments, and an articulate support assembly. Each instrument is insertable into a patient through an associated minimally invasive aperture to a desired internal surgical site. The articulate support assembly movably supports the instruments relative to the base. The support generally comprises an orienting platform, a platform linkage movably supporting the orienting platform relative to the base, and a plurality of manipulators mounted to the orienting platform, wherein each manipulator movably supports an associated instrument.

Abstract: An ablation electrode system includes a handle assembly; a needle electrode assembly supported in and extending from the handle assembly. The needle electrode assembly includes an outer tube having at least a conductive distal tip and defining a cavity therein; and an inner tube disposed at least partially within the cavity of the outer tube and defining a lumen therein. The ablation electrode assembly includes a hub assembly fluidly connected to the needle electrode assembly. The hub assembly defines a first chamber and a second chamber; wherein the proximal end portion of the inner tube is in fluid communication with the first chamber and the proximal end portion of the outer tube is in fluid communication with the second chamber. The ablation electrode assembly includes a first fluid conduit fluidly connected to the first chamber; and a second fluid conduit fluidly connected to the second chamber.

Abstract: The invention relates to a method and an apparatus for influencing magnetic particles in a region of action. With the help of an arrangement that has means for generating magnetic fields, a spatially inhomogeneous magnetic field is generated that has at least one zone (301) in which the magnetization of the particles is in a state of non-saturation, whereas it is in a state of saturation in the remaining zone. By displacing the said zone within the region of action, a change in magnetization is produced that can be detected from outside and that gives information on the spatial distribution of the magnetic particles in the region of action. Alternatively, the displacement may also be repeated so frequently that the region of action heats up. To improve the accessibility of the region of action, the said region is situated outside the arrangement having means for generating magnetic fields.

Abstract: Methods and apparatus for cryo-therapy are disclosed herein. This includes a hollow guidewire disposed within a catheter having helical loops contacting tissue. A coolant delivery tube disposed within can have a coolant delivered from a proximal end into the guidewire lumen. The coolant flows back proximally through the guidewire while cooling the guidewire surface and cooling or cryogenically ablating the contacting tissue. To minimize guidewire exposure to surrounding fluids or tissue, insulative barriers can be attached to the guidewire. A coolant delivery tube and return lumen can be integrated from a single extrusion in various configurations. Expandable balloons can also be used to expand the loops of the guidewire to contact the tissue. Also, helical loops with a coolant delivery tube or stem disposed longitudinally within the loops can be used and the loops can also have a variable collapsible cooling region.

Abstract: The present invention encompasses a heat exchange catheter for indirect cooling of internal organs, particularly the heart. The heat exchange catheter is inserted into the esophagus and a cooled fluid is circulated within the catheter, cooling the esophagus, and by conduction, the heart. The heat exchange catheter or the invention may be rapidly deployed in the field and is particularly useful for preventing and reducing tissue damage caused by ischemia.

Abstract: Methods and systems for transvenously accessing the pericardial space via the vascular system and atrial wall, particularly through the superior vena cava and right atrial wall, to deliver treatment in the pericardial space are disclosed. A steerable instrument is advanced transvenously into the right atrium of the heart, and a distal segment is deflected into the right atrial appendage. A fixation catheter is advanced employing the steerable instrument to affix a distal fixation mechanism to the atrial wall. A distal segment of an elongated medical device, e.g., a therapeutic catheter or an electrical medical lead, is advanced through the fixation catheter lumen, through the atrial wall, and into the pericardial space. The steerable guide catheter is removed, and the elongated medical device is coupled to an implantable medical device subcutaneously implanted in the thoracic region. The fixation catheter may be left in place.

Abstract: Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, various beam focusing techniques to reduce scattering and/or other techniques for reducing the cost and/or increasing the efficacy of optical radiation for use in hair removal and other dermatological treatments. A number of embodiments are included for achieving the various objectives indicated above.

Abstract: A catheter is provided having anchoring and stabilizing devices adapted to respectively sit in and outside an opening of a tubular region. A sheath covering the catheter body forms the anchoring and stabilizing devices, which sheath comprises slits cut into the sheath creating spines. The spines are radially expanded by distal movement of the sheath relative to the catheter body. Radial expansion of the anchoring device generally anchors the distal end of the catheter inside the tubular region. Radial expansion of the stabilizing assembly generally stabilizes the distal end of the catheter against the ostium of the tubular region. The pressure exerted on the tubular region by the anchoring and stabilizing devices minimizes translational and rotational movement of the distal end of the catheter. Alternatively, the catheter may include a telescoping portion extending from the distal end of the catheter in which the anchoring and stabilizing devices are deployed by movement of a puller wire.

Abstract: A cryogenic catheter includes an outer flexible member having at least one cryogenic fluid path through the flexible member. The at least one fluid path is defined by a plurality of flexible members disposed within the outer flexible member.

Abstract: Devices and methods for the treatment of skin conditions and lesions are disclosed herein. One aspect of the invention is a compact hand held device that can be safely used by those suffering from skin conditions, such as acne, warts, cold blisters, blemished skin, or fine wrinkles. The devices described herein employ the application of heat for the treatment of skin conditions and lesions. Typically, the peak temperatures employed are about 70° C. to about 400° C. by the devices, are achieved in less than about 1 second, and maintained for less than about 1 second. In some embodiments, the skin surface is heated with heat pulses. Thermal conduction transfers heat from the device to the skin and causes a biological response that accelerates acne clearing, treats blemished skin, itching, or fine wrinkles. The total heat transferred is low enough to prevent burns.

Abstract: A forced air warming unit has a casing with inlet and outlet openings. The casing encloses a scroll housing with a curved inside surface in which a blower is disposed. A circuit board in the casing encloses the blower in the scroll housing. At least one opening penetrates the circuit board. A heater plate is disposed between the circuit board and the blower. The blower draws air through the inlet opening, along a first side of the circuit board through the at least one opening into the scroll housing. The blower also forces air along a second side of the circuit board which faces the scroll housing, through air passages in the circuit board, along the first side through the at least one opening, into the scroll housing. The blower accelerates air along the curved inside surface and past the heater plate. Heated, pressurized air exits through the outlet opening.

Abstract: Apparatus and methods for the treatment of keratinized tissue infected with a pathogen are provided. In certain examples, electromagnetic energy, such as microwave energy, may be used in the treatment process to reduce the amount of or eliminate the pathogen from the keratinized tissue.

Abstract: The present invention relates to the field of electrosurgery, and more particularly to systems and methods for ablating, cauterizing and/or coagulating body tissue using radio frequency energy. More in particular, the systems utilize voltage threshold means for controlling the voltage applied to tissue in a cycle-to-cycle manner.

Abstract: A thermal treatment garment of the present invention includes an outer structure layer, an interior lining formed of a gel material that directly contacts a body portion of a user when the garment is worn by the user and a thermal treatment layer to thermally treat and control temperature of the garment. The thermal treatment layer heats and/or cools the gel material to a selected temperature or selected temperature range and is controlled by a controller. In an exemplary embodiment, the garment includes a cap to thermally treat the user's head, where the structure layer has a generally convex outer surface and the interior surface of the gel layer is generally concave and contoured to engage with and at least partially envelop at least one selected portion of the user's head.

Abstract: The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.