Abstract: A system includes a dilation catheter and a guide member. The dilation catheter includes a proximal end, a distal end, a dilator, a navigation sensor, and a force sensor. The dilator is positioned proximal to the distal end and is configured to transition between a non-dilated configuration and a dilated configuration. The navigation sensor is positioned distal to the dilator and is configured to cooperate with a guidance system and thereby provide signals indicating a position of the dilation catheter in three-dimensional space. The force sensor is positioned distal to the dilator and is configured to provide signals indicating a force encountered by the force sensor. The dilation catheter is configured to slide relative to the guide member. A distal portion of the guide member is sized and configured to fit in a nasal cavity of a patient.

Abstract: The present disclosure is directed to a branched endoprosthesis comprising a graft component and at least one support component. In various embodiments, the branched endoprosthesis comprises a body portion and a plurality of leg portions, wherein the legs are in an aligned configuration for ease of cannulation. In various embodiments, at least one leg is in an open configuration for ease of cannulation. Cannulation methods are also described.

Abstract: The present disclosure relates to a self-expanding braided implant, including a distal implant end and a proximal implant end, the braided implant being invertible about the distal implant end. Translation of the braided implant distally causes the braided implant to invert and fold into itself thereby forming an occlusive sack configured to occlude the aneurysm.

Abstract: A guidewire including a thin elongated structure and an outer shell around at least a portion of the thin elongated structure. The outer shell includes a first portion and a second portion. The first portion and the second portion of the outer shell are each coupled to the thin elongated structure. The first portion is spaced from the second portion by a gap. The guidewire is configured to move between a flexible state and a rigid state. The gap has a first distance when the guidewire is in the flexible state and the gap has a second distance greater than the first distance when the guidewire is in the rigid state.

Abstract: An endovascular apparatus includes a first cannula, a second cannula, and an operator handle. The first cannula has a proximal end, a distal end, and a first lumen. The second cannula is slidably coupled to the first cannula. The second cannula has a proximal end portion, a distal end portion, and a second lumen. The distal end portion is extendable in a distal direction beyond the distal end of the first cannula. The operator handle is operably coupled to the second cannula. The operator handle may be configured to articulate the distal end portion of the second cannula relative to the first cannula. The second cannula may include an articulation joint. Optionally, the operator handle may be configured to extend, retract, and rotate the second cannula relative to the first cannula. Also, optionally, the endovascular apparatus may include a magnetic coupler.

Abstract: Disclosed are methods and devices for obtaining patent hemostasis of the radial artery by compressing the uninstrumented ulnar artery to increase radial artery flow. The device comprises a band having an inflatable bladder for applying blunt pressure to the ulnar artery. The method comprises applying a pressure to the homolateral ulnar artery and applying a pressure to the radial artery at the access site to obtain hemostasis at the access site.

Abstract: A hemostatic device is provided to stop bleeding at a puncture site on an artery of a patient, the device comprising a transparent flexible band to be wrapped at the site where the bleeding is to be stopped, a curved compression member having an inner peripheral side and possessing a first curved portion in its first half and a second curved portion in its second half, a first balloon provided on the inner peripheral side in the first half of the curved compression member and a second balloon provided on the inner peripheral side in the second half of the curved compression member. The bleeding from a first artery is stopped by compressing the first artery at the puncture site using inflation of the first balloon and blood flow in the first artery is increased by compression of a second artery using inflation of the second balloon.

Abstract: A surgical clip may include first and second leg members, each having inner surfaces. The inner surface of the first leg member may be concave and the inner surface of the second leg member may be convex. The surgical clip may include a first locking member positioned on a distal end portion of the first leg member, and a second locking member positioned on a distal end portion of the second leg member. The surgical clip may also include a third locking member position between a proximal end portion and the distal end portion of the first leg member, and a fourth locking member positioned between a proximal end portion and the distal end portion of the second leg member. The first and second locking members, and the third and fourth locking members may be configured to interact to secure the surgical clip in a closed configuration.

Abstract: Disclosed herein are devices and methods for removing tissue. In one aspect, a device for removing tissue includes a hollow elongate member having an outer wall and a lumen, a selectively deployable tissue-cutting element extending from the hollow elongate member, and an actuation member extending through the lumen and coupled to the hollow elongate member at a location that is distal to the tissue-cutting element. Movement of the actuation member can cause the tissue-cutting element to move from the insertion configuration where the tissue-cutting element is not deployed to a tissue-cutting configuration where the tissue-cutting element is deployed such that it is radially extended relative to the insertion configuration.

Abstract: A radial artery sheath assembly includes a cuff that is wearable around a patient's wrist and a receiver is integrated into the cuff. The cuff is inflatable to compress an incision in the patient's wrist to achieve homeostasis for stopping bleeding. A ring is removably attachable to the cuff and a radial sheath is extendable through the ring to retain the radial sheath in the incision in the user's wrist when the ring is attached to the cuff. The ring is inflatable for compressing the radial sheath in the ring to inhibit the radial sheath from being removed from the incision. A lock is coupled to the ring and the lock releasably engages the receiver in the cuff for attaching the ring to the cuff.

Abstract: The devices and methods described herein relate to jointless construction of complex structures. Such devices have applicability in through-out the body, including clearing of blockages within body lumens, such as the vasculature, by addressing the frictional resistance on the obstruction prior to attempting to translate and/or mobilize the obstruction within the body lumen.

Abstract: A clamp includes upper clamp assemblies, lower clamp assemblies, a base, a locking unit, a connecting rod arm, expandable arms and a central occluding woven net. The upper clamp assemblies and the lower clamp assemblies are quantitatively identical and cooperate in opening and closing to form a clamping portion. The clamp can effectively occlude the regurgitation on two sides of the clamp through the expandable arms on the two sides. By means of the central occluding woven net, the clamp can further reduce the central regurgitation, decrease the stress on the leaflet and prevent the damage to the leaflet; and the clamp firmly closes the lower clamp assemblies in a mechanical locking manner, such that the clamp does not drop easily after implanted into the body. The clamp can be implanted through the femoral vein puncture and transseptal puncture (TSP) with minimal invasion, to repair the mitral valve.

Abstract: A branched and fenestrated prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. The branched and fenestrated prosthesis may include a plurality of branches and a plurality of fenestrations.

Abstract: A system and method for cutting soft tissue with a retractable surgical cutting device (10). The device (10) includes a handle (12) having a first channel (24) extending therethrough and a switch (18) located thereon. The switch (18) is movable between a retracted position and an extended position. An actuator (26) with a blade (16) extends through the first channel (24) and connects to the switch (18) within the handle (12). An outer sheath (14) is connected to the handle (12) and surrounds the actuator (26) and at least a portion of the blade (16). A drive mechanism (28) is connected to the switch (18) within the handle (12) such that when the switch (18) moves from the retracted position to the extended position, the actuator (26) moves from a retracted position to an extended position. In the retracted position, the blade (16) can be entirely within the outer sheath (14) and in the extended position, at least a portion of the blade (16) is positioned outside of the outer sheath (14).

Abstract: Disclosed embodiments provide a biopsy tool and methodologies for obtain biopsies and/or a tool and methodology that may be used to add material to a subject's tissue.

Abstract: A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.

Abstract: An end effector for a surgical clip applier includes a housing, and jaws that include opposed first and second jaw members each comprising an independent structure movable relative to the other, the first jaw member defining a first inner surface and the second jaw member defining a second inner surface opposite the first inner surface. An actuation mechanism is arranged within the housing and is operable to move the jaws between an open position and a closed position, the actuation mechanism including a linear drive that provides transition pins engageable with angled slots defined in the first and second jaw members. Linear movement of the linear drive moves the jaws between the open and closed positions, and the first and second inner surfaces remain substantially parallel to each other as the jaws move between the open and closed positions.

Abstract: A cutting device for surgical threads comprises a guide body that has an internal axial cavity and a first cutting area defined by an abutment surface; a cutting body that has a central portion that extends along a longitudinal axis and a second cutting area defined by an abutment surface, wherein the second cutting area abuts the second first cutting area when the cutting body is received in a housing portion of the guide body; and an actuator element capable of causing the cutting body to rotate relative to the guide body about the longitudinal axis between a first position, in which the first and second cutting areas, define a passageway that communicates with the internal axial cavity, and a second position, in which said passageway is at least partially obstructed by a counter-rotating movement of the abutment surfaces, which intersect tangentially so as to cut the surgical thread therebetween.

Abstract: A magnetic vascular anastomosis device for rapid liver transplantation includes a magnetic ring assembly and a base member assembly. The magnetic ring assembly includes an O-shaped magnetic ring and a C-shaped magnetic ring coupled at a donor liver blood vessel and a receptor liver blood vessel respectively. The base member assembly includes an O-shaped base member and a C-shaped base member. The base member is categorized into a slotted base member, a columned base member, and a hooked base member for different surgical suture methods. The magnetic vascular anastomosis device incorporates with the magnetic attraction between magnetic rings, such that the entire liver transplantation vascular anastomosis process is fast, safe, and reliable. The vascular anastomosis device is able apply for different operations involving vascular anastomosis such as kidney transplantation, lung transplantation, heart transplantation, and maxillofacial surgery.

Abstract: An endoscopic clip apparatus includes a clip sleeve defining an interior passage along a longitudinal axis and having a distal end with a plurality of openings defined in the distal end. A clip including a plurality of arms is disposed in the clip sleeve, and each arm includes a distal tip extending from the clip sleeve through one of the plurality of openings. Each arm includes a convex curved section oriented away from the longitudinal axis. The clip sleeve and clip are axially moveable relative to each other such that when the clip sleeve travels over the convex curved section of each arm toward the distal tip of each arm, each arm is constrained by the clip sleeve and each distal tip advances toward the longitudinal axis to grasp tissue.