Abstract: The present invention relates to the use of nitrogen-containing complexing agents for deodorization and antimicrobial treatment of the skin and of textile fiber materials. The complexing agents employed according to the invention have the formula in which Q1, is Carb1; Carb2,; or a radical of the formula —(CH2)m1—OH; Q2 is hydrogen or Carb2; and Q3 is Carb3; an amino acid radical; or a radical of the formula where Carb1, Carb2 and Carb3 independently of one another are the radical of a C1-C8-mono- or -dicarboxylic acid and m1 is 1 to 5. The complexing agents according to the invention show a pronounced bacteriostatic action against Corynebacterium xerosis (bacteria which cause body odour) and are therefore suitable as the antimicrobial active substance in body care compositions and antimicrobial fabric finishing of textile materials.

Abstract: Methods to elevate white blood cell counts in animal subjects using compounds of formula (1) are disclosed.

Abstract: The present invention provides a novel chewing gum product generally for the lysis and killing of oral microbes. In a preferred embodiment, the chewing gum product comprises an antimicrobial metal ion component and an inorganic ceramic carrier, and provides a concentration of such substances from about 0.05 to 50 weight percent of the chewing gum. In particular, these compositions may comprise zeolites ion-exchanged with antimicrobial metals, in addition to other oral care compounds. The present invention also relates to methods of using such compositions for treating and inhibiting dental caries, dental plaque and gingivitis, oral malodor and periodontal conditions. The compositions of the present invention may be incorporated into chewing gum according to conventional methods used in the art.

Abstract: The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. The methods comprise the step of orally administering to a mammal, such as a human, a therapeutically effective amount of one or more fat-binding polymers. The administration of the fat-binding polymer of the invention facilitates the removal of fat from the body prior to digestion, with minimal side effects and low toxicity. In a preferred embodiment, the one or more fat-binding polymers are administered in combination with one or more lipase inhibitors, for example, lipstatin and tetrahydrolipstatin.

Abstract: The present invention relates to a solid dosage form comprising at least one polymeric binder and at least one active ingredient and, where appropriate, conventional additives, wherein the polymeric binder consists of copolymerized units a) 15-83% by weight of at least one N-vinyllactam, b) 15-83% by weight of methyl methacrylate, c) 2-70% by weight of at least one other monomer and d) 0-9.9% by weight of at least one &agr;,&bgr;-ethylenically unsaturated acid.

Abstract: The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. The methods comprise the step of orally administering to a mammal, such as a human, a therapeutically effective amount of one or more fat-binding polymers. The administration of the fat-binding polymer of the invention facilitates the removal of fat from the body prior to digestion, with minimal side effects and low toxicity. In a preferred embodiment, the one or more fat-binding polymers are administered in combination with one or more lipase inibitors, for example, lipstatin and tetrahydrolipstatin.

Abstract: A method for increasing the effectiveness of a biocide is described. In the method, at least one biocide and at least one diethanolamide are applied to a substrate or aqueous system subject to the growth of microorganisms. The diethanolamide is applied in an amount effective to increase the biocidal activity of the biocide. Biocidal compositions are described where the biocide and the diethanolamide are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described. The combination of the biocide and the diethanolamide is particularly useful as a biocide in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in industrial process waters.

Abstract: A method of treating hypertension and related symptoms thereof is described. A suspension of small, unilamellar vesicles composed primarily of phospholipids similar in nature to those of egg phosphatidylcholine is administered parenterally to a subject in need of such treatment repeatedly and over an extended period of time of at least several days, until a significant drop in blood pressure is observed.

Abstract: The present invention provides a topical pharmaceutical composition for wound healing, which comprises (a) borneol and (b) bismuth subgallate in effective amounts. The topical pharmaceutical composition is capable of enhancing wound healing with minor irritations to injured skin, and preventing formation of scars or granulation tissues so as to help regenerate the skin with normal tenderness and appearances.

Abstract: Compositions and methods for use in preventing conception or treating benign gynecological disorders, wherein an effective amount of an antiprogestational agent [e.g., progesterone (progestin, progestogen, gestagen) antagonist or progesterone synthesis inhibitor] administered over a first period of time is combined with an effective amount of a progestogen for a second period of time. The antiprogestational agent is selected from single agents or mixtures thereof. The progestogen is selected from single agents or mixtures of natural or synthetic progestogens. The formulations are effective as contraceptive agents and for treatment of benign gynecological disorders including uterine fibroids, premenstrual syndrome, dysfunctional uterine bleeding, polycystic ovarian syndrome and endometriosis.

Abstract: The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula: wherein R, R′, R1, R′1, R2, R′2, R3, R′3, R4, R′4, R5, R′5, R6, R′6, R7, R′7, R8, R′8, R9, R′10, R10 and R′10, X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, myocardial infarction, stroke, atherosclerosis, and all other conditions of oxidant-induced tissue damage or injury.

Abstract: Methods of using the chromium(III) complex represented by the formula [Cr3O(O2CCH2CH3)6(H2O)3]+ as a nutritional supplement.

Abstract: The claims define a method which is based on the use of baclofen to suppress the cough of a patient who is afflicted with a cough that is induced by the administration of an ACE inhibitor. The usual dose of baclofen is from 10 to 30 mg daily. A pharmaceutical composition which comprises an effective amount of an ACE inhibitor is also disclosed which is a combination of an ACE inhibitor and an amount of baclofen which is effective to suppress the cough which is caused by the administration of the therapeutic dose of an ACE inhibitor.

Abstract: Compositions, medicaments, and methods for the promotion of hair growth are disclosed. These compositions and medicaments are comprised of either local anesthetics of the secondary or tertiary amino type or niacin. The preferred secondary and tertiary amino compounds include those which are esters of para-aminobenzoic acid, esters of benzoic acid, esters of meta-amino benzoic acid, amides, ethers, and ketones. The preferred compositions and medicaments include either procaine hydrochloride or niacin or procaine hydrochloride and niacin in a non-sulfur-containing carrier. The disclosed compositions and medicaments may be topically applied to a scalp in need thereof by an eyedropper or other suitable means. An improved embodiment of this application adds minoxidil.

Abstract: An aqueous or aqueous/alcoholic cosmetic composition which can be sprayed, comprising an aqueous dispersion of insoluble film-forming polymer particles and at least one insoluble silicone, wherein the polymer particles are present in a concentration greater than 15%, relative to the total weight of the composition, and further wherein the glass transition temperature of the insoluble polymer particles ranges from 15 to 35.degree. C. The invention also relates to a process for the cosmetic treatment of keratinous substances using these compositions and to the use of the silicone for improving the quality of the spraying of the composition.

Abstract: A kit which is adapted and designed to provide both data on the current reproductive status of a patient, and contraception for those who are not pregnant, but recently engaged in unprotected sex.