Abstract: Derivatives of glutamic and aspartic of formula (I) are described ##STR1## where the compounds are potent receptor antagonists of gastrin at the peripheral level and of cholecystokinin at the level of the central nervous system.
Type:
Grant
Filed:
April 8, 1996
Date of Patent:
October 5, 1999
Assignee:
Rotta Research Laboratorium S.p.A.
Inventors:
Francesco Makovec, Walter Peris, Lucio C. Rovati, Luigi A. Rovati
Abstract: The hetero-linked phenylglycinolamides are prepared by reaction of the corresponding hetero-linked phenylacetic acids with appropriate phenylglycinols. The hetero-linked phenylglycinolamides are suitable as active compounds in medicaments.
Type:
Grant
Filed:
April 10, 1997
Date of Patent:
April 6, 1999
Assignee:
Bayer Aktiengesellschaft
Inventors:
Siegfried Goldmann, Ulrich Muller, Richard Connell, Hilmar Bischoff, Dirk Denzer, Rudi Grutzmann, Martin Beuck