Abstract: A real-time in-situ sensor system is provided for measurement of bioluminescence and determination of bioluminescence surface signature. The system measures bioluminescence in the wake of a submerged moving object as well as ambient light levels outside of the wake. Along with measurements of depth and water-quality parameters including turbidity, temperature and salinity, the surface signature of the induced underwater bioluminescence can be calculated by considering light transmission and attenuation through water. With this real-time information, the operator of the submerged moving object can employ tactical maneuvers to affect the resultant surface signature.

Abstract: The present invention relates to a diagnostic kit and more specifically to a self contained diagnostic kit providing analysis of a sample by a sample collectin element and an immunochromatography test strip.

Abstract: An object of the present invention is to solve the problems in conventional art antigen exposure chambers, and specifically, to provide an antigen exposure chamber system capable of simultaneously exposing a large number of test objects in a chamber to a uniform antigen (pollen, mite or house dust, etc.) in all seasons.

Abstract: A test system comprises a sensor container and a testing device. The sensor container has a base and a lid. The container encloses test sensors therein. The container includes a calibration label attached thereto. The label includes electrical contacts located thereon. The electrical contacts encode calibration information onto the calibration label. The testing device has an auto-calibration feature externally located thereon. The testing device is adapted to determine the analyte concentration in a fluid sample. The auto-calibration feature includes calibration elements that communicate with the electrical contacts on the calibration label. The testing device is adapted to determine the calibration information encoded on the calibration label in response to the calibration elements engaging the electrical contacts. The encoded calibration information is determined without inserting the sensor container or the calibration label into the testing device.

Abstract: In an analyzer for analyzing a sample that reacts with a reagent 25, an analyzing tool 10, an infrared sensor 1 and a temperature controlling part 5 are provided. Inside the analyzing tool 10, a reaction cell 24 in which the sample and the reagent 25 react with each other and a heating element 33 that is heated by electrification are provided. The infrared sensor 1 is disposed outside the analyzing tool 10 so as to photoreceive an infrared ray 9 that is emitted from the reaction cell 24, and outputs a signal that is in accordance with an amount of the photoreceived infrared ray 9 to the temperature controlling part 5. The temperature controlling part 5 adjusts a heat value of the heating element 33 based on the signal from the infrared sensor 1.

Abstract: A fluid system that includes a flow system for a liquid having an inlet, an outlet, at least one fluid line extending from the inlet to the outlet and an electrically activatable melting device, wherein activation of the melting device causes melting, which interrupts, stops or diverts a flow of the fluid through the flow system. In one embodiment, the fluid system may be used in a device for measuring blood sugar.

Abstract: A microfluidic device for preparing a mixture, has a mixer. The mixer includes a plurality of chambers, each chamber having a volume of at most 1 microliter, a first plurality of channels, each channel fluidly connecting 2 chambers, a plurality of chamber valves, each chamber valve controlling fluid flow out of one of the plurality of chambers, and a first plurality of channel valves, each channel valve controlling fluid flow through one of the first plurality of channels.

Abstract: A method and system for defect localization includes: (i) receiving a test structure that includes at least one conductor that is at least partially covered by an electro-optically active material; (ii) providing an electrical signal to the conductor, such as charge at least a portion of the conductor; and (iii) imaging the test structure to locate a defect.

Abstract: Provided is a method of manufacturing a biochip using a droplet discharging device including a droplet discharging head having a cavity and a nozzle hole provided in communication with the cavity, and a liquid housing unit connected to the cavity via a passage, having the steps of filling a retention liquid which separates without getting mixed with the sample liquid into the liquid housing unit, the passage, and the cavity; injecting the sample liquid into the liquid housing unit; moving the sample liquid from the liquid housing unit to the cavity by discharging the retention liquid from the nozzle hole; stopping the discharge of the retention liquid at the moving step upon detecting with a sensor that the sample liquid reached a position adjacent to the nozzle hole; and delivering the sample liquid as droplets onto the object by discharging the sample liquid from the nozzle hole.

Abstract: A microfluidic device for the concentration and lysis of cells or viruses and a method of concentrating and lysing cells or viruses using the microfluidic device include: magnetic beads, a reaction chamber in which the magnetic beads are accommodated and a laser source. The reaction chamber includes a plurality of electrodes which cross each other and are separated by a dielectric to generate an electric field and a vibrating part agitating the magnetic beads in the chamber. The laser source radiates a laser onto the magnetic beads in the reaction chamber.

Abstract: The present invention provides an apparatus, comprising a first mechanical structure having a first rigid surface, an area of the first rigid surface having a nanostructured surface. The apparatus also includes a second mechanical structure having a second rigid surface and opposing the first mechanical structure. The second rigid surface is cooperable with the nanostructured surface such that a microscopic particle is locatable between the nanostructured surface and the second rigid surface.

Abstract: A drape including a sensing device according to the present invention is disposed over a top surface of a thermal treatment system having a basin recessed therein. A portion of the drape is pushed down into the basin to form a drape container for collecting a sterile medium. The thermal treatment system may be of the type that either heats or congeals the sterile medium. The sensing device includes electrodes that are typically disposed through the drape and sealed. The electrodes provide signals indicating the presence of liquid and/or leaks or other conditions within the drape container to the system to facilitate control of system operation. In addition, the sensing device includes a fuse to limit the drape to a single use. The system disables the fuse to indicate prior use and detects tampering to bypass the fuse, thereby preventing use of the drape for subsequent medical procedures.

Abstract: A sample block for use in the polymerase chain reaction, DNA sequencing, and other procedures that involve the performance of simultaneous reactions in multiple samples with temperature control by heating or cooling elements contacting the bottom surface of the block is improved by the inclusion of hollows in the block that are positioned to decrease the mass of the block in the immediate vicinity of the wells.

Abstract: Methods for determining chlorine demand in water are provided. One method comprises (a) providing a test water sample containing at least one contaminant and a source of chlorine and a source of bromide; (b) heating the test water sample for a suitable time and temperature sufficient to substantially oxidize the at least one contaminant in the test water sample; and (c) determining the content of residual chlorine present in the test water sample.

Abstract: The invention relates to compositions, kits and methods used in hydroxyl radical detection. In some embodiments, the invention relates to compositions comprising a dye preferably methylene blue immobilized on a substrate. In additional embodiments, the invention relates methods of correlating color changes of a dye to the presence or absence of hydroxyl radicals. In some embodiments, the invention relates to a methylene blue dye containing test strip and its use in a method for detecting the presence of hydroxyl radicals.

Abstract: A tissue cassette assembly includes a housing having a recess formed therein, and a compressible reservoir disposed partially or wholly inside of, or otherwise attached in fluid communication with, the housing recess, the compressible reservoir containing a tissue embedding material. The tissue cassette further includes a port disposed in the housing, the port in fluid communication with the compressible reservoir at one end and terminating in a sample cavity at another end. During operation, the compressible reservoir is compressed or squeezed to release the tissue embedding material into the sample cavity containing the biological sample.

Abstract: A system for detecting at least one contamination species in an interior space of a lithographic apparatus, including: at least one monitoring surface configured to be in contact with the interior space, a thermal controller configured to control the temperature of the monitoring surface to at least one detection temperature, and at least one detector configured to detect condensation of the at least one contamination species onto the monitoring surface.

Abstract: An apparatus for disruption of cells or viruses using a laser and magnetic beads includes a cell lysis chip including a sample inlet hole into which a sample and the magnetic beads are introduced, a vibrator fixing the cell lysis chip and transferring vibrations in a prescribed direction, a laser generator supplying the laser to the cell lysis chip and a controller controlling operations of the vibrator and the laser generator.

Abstract: A fluid system that includes a flow system for a liquid having an inlet, an outlet, at least one fluid line extending from the inlet to the outlet and an electrically activatable melting device, wherein activation of the melting device causes melting, which interruptes, stops or diverts a flow of the fluid through the flow system. In one embodiment, the fluid system may be used in a device for measuring blood sugar.

Abstract: A foldable instrument (10) adapted to determine an analyte concentration of a fluid sample using a test sensor is disclosed. The instrument comprises a first portion (12) including a display (22) and a second portion (14) pivotally coupled to the first portion by a pivot mechanism (23). The second portion includes a user-interface mechanism (16a-c). One of the first portion (12) and second portion (14) includes at least one opening (18) formed therein. The opening is adapted to receive a test sensor. The instrument is adapted to be folded into a closed position and unfolded into an open position by rotating one of the first portion and second portion about the pivot mechanism (23).