Patents Examined by Samala Jagadishwar
  • Ocular diagnosis of Alzheimer's disease
    Patent number: 7297326
    Abstract: The invention features a method of diagnosing or providing a prognosis regarding the state of Alzheimer's Disease in a mammal by contacting an ocular tissue with a detectably-labeled compound, which binds to an amyloid protein. An increase in binding of the compound to the ocular tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing Alzheimer's Disease.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: November 20, 2007
    Assignees: The General Hospital Corporation, The Brigham and Women's Hospital, Inc.
    Inventors: Lee E. Goldstein, Leo T. Chylack, Jr.