Abstract: The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
Type:
Grant
Filed:
July 4, 2013
Date of Patent:
October 21, 2014
Assignee:
Angion Biomedica Corp.
Inventors:
Bijoy Panicker, Dong Sung Lim, Rama K. Mishra, Lambertus J. W. M. Oehlen, James G. Tarrant, Xiaokang Zhu, Dawoon Jung
Abstract: The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof. The compound of the present invention has a glucokinase activity, and is useful as a medicament such as an agent for the prophylaxis or treatment of diabetes, obesity and the like, and the like.
Type:
Grant
Filed:
April 25, 2008
Date of Patent:
November 27, 2012
Assignee:
Takeda Pharmaceutical Company Limited
Inventors:
Tsuneo Yasuma, Kentaro Hashimoto, Masahiro Ito