Patents Examined by Sameena Ahmed
  • Process for the preparation of thiazole derivatives
    Patent number: 6476230
    Abstract: The present invention relates to intermediate thiazole compounds and a process for preparing 2-chloro-5-chloromethylthiazole which is a known compound useful for the preparation of insecticides.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: November 5, 2002
    Assignee: Syngenta Crop Protection, Inc.
    Inventor: Kevin Coppola
  • Protein tyrosine phosphatase inhibitors
    Patent number: 6472545
    Abstract: Compounds of formula (I) or therapeutically acceptable salts thereof, are protein tyrosine kinase PTP1B inhibitors. Preparation of the compounds, compositions containing the compounds, and treatment of diseases using the compounds are disclosed.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: October 29, 2002
    Assignee: Abbott Laboratories
    Inventors: Gang Liu, Zhonghua Pei
  • Polypyrrolinone based inhibitors of matrix metalloproteases
    Patent number: 6455570
    Abstract: A compound of the formula wherein: R1, R2, R3, R4, R5, R6 are as defined herein, useful for the inhibition of inhibition of matrix metalloproteases (MMPs)and for treating conditions mediated by elevated levels of MMPs such as osteoarthritis, rheumatoid arthritis, septic arthritis, periodontal disease, gingivitis, solid tumor growth and tumor invasion by secondary metastasis, corneal ulceration, dermal ulceration, epidermolysis bullosa, neural degeneration, multiple sclerosis and surgical wound healing.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: September 24, 2002
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Amos B. Smith, III, Ralph F. Hirschmann, Thomas Nittoli, Paul Sprengeler