Patents Examined by Samuel Bark
  • Method of producing halogenated and alpha-aminoalchohols
    Patent number: 5523463
    Abstract: A process for the manufacture of N-protected .alpha.-aminoketones and N-protected .alpha.-aminoalcohols of the formula ##STR1## wherein X is halogen, one of Q.sup.1 and Q.sup.2 is hydrogen and the other is hydroxy or Q.sup.1 and Q.sup.2 together are oxo, R.sup.1 is an amino protecting group and R.sup.2 is hydrogen or the characterizing group of an .alpha.-aminocarboxylic acid,starting from the corresponding lower alkyl N-protected .alpha.-aminocarboxylates via corresponding lower alkyl N-silyl protected .alpha.-aminocarboxylates.
    Type: Grant
    Filed: August 21, 1995
    Date of Patent: June 4, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Hans Hilpert