Abstract: A system and method for a therapeutic apparatus that includes an external casing of a first therapeutic apparatus, wherein the external casing comprises of a plush body, the external casing comprising at least one compartment; a therapeutic module system that comprises of a set of interaction devices and a wireless communication system, wherein the therapeutic module system may be removably oriented into the at least one compartment; the set of interaction devices comprising of: sensing inputs that comprise of a auditory sensing system, a haptic sensing system, an olfaction sensing system, and other biosensing systems, and output systems that comprise of at least an auditory feedback and haptic feedback systems; and a processing system that comprises configuration to assess the state of a subject through the sensing inputs and control the output systems in response to the sensing inputs.

Abstract: Apparatus, methods and systems for treating venous occlusive disease are provided. Generally, devices include a removable soft extension member that is adapted to be mounted at a proximal end of a therapeutic vacuum chamber. The soft extension member includes a proximal end composed of a tissue contacting portion configured to receive a tissue to be treated, and a distal end composed of a collar configured to be mounted onto an exterior surface of a vacuum chamber. Apparatus, methods and systems for increasing penile and cavernosal tumescence by application of a vacuum are also provided.

Abstract: An apparatus for applying an electron beam to a subdermal tumor generates a pulsed electron beam that is collimated to a diameter of less than 1 mm and less than 10 millimeter-milliradiant transverse emittance. A biopsy needle having an interior diameter less than 2 mm and length between 1 cm and 100 cm is inserted through the skin to the tumor, and the electron beam is electromagnetically directed through the needle, so as to reach the tumor without irradiating intervening normal tissue and with minimal irradiation of surrounding normal tissue. The electron pulsing rate can be in the S-band or Q-band, the beam energy can be between 1 Mev and 6 MeV, and/or the beam brightness can be less than 10 mm·mrad. A distal end of the biopsy needle can include an electron-permeable vacuum barrier, and the apparatus can be evacuated to less than 10?8 Torr.

Abstract: Apparatus, methods and systems for treating venous occlusive disease are provided. Generally, devices include a soft extension member that is adapted to be mounted at a proximal end of a therapeutic vacuum device. The soft extension member includes a proximal end composed of a tissue contacting portion configured to receive a tissue to be treated, and a distal end composed of a collar configured to be mounted onto an exterior surface of a vacuum chamber. Apparatus, methods and systems for increasing clitoral and cavernosal tumescence by application of a vacuum are also provided.

Abstract: Children who experience anxiety associated with novel situations react physically and emotionally in ways that make it challenging for the child, parents, educators, and providers to proceed with the intended goal of that novel situation. Anxiety in children can be reduced by introducing fun or distracting stimuli that act on specific neural pathways. The stimuli introduced can familiarize a child with the environment in which the procedure will take place and the equipment and people which the child will meet. In the healthcare setting, by using consistent stimuli, and by disrupting anxiety at one or more of a series of stages in which anxiety typically occurs, a reduction in needed anesthesia can be achieved, which is healthier for the child and reduces the costs associated with the medical or dental procedure.

Abstract: A dildo and harness plate formed of a contoured member adapted to comfortably fit and secure an elongated member to the pubic region and perineal regions of a donning user while enabling comfortable access to the donning user's genitals and providing a variety of configurations for connections mounts for comfortably securing the device with straps and connectors.

Abstract: An apparatus comprising: at least one processor; and at least one memory including computer program code, the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus to perform at least the following: receive respective sleep profiles of a plurality of users, each sleep profile comprising recorded sleep phases of a sleep session of a respective user of the plurality of users, receive a target sleep outcome of the plurality of users; and based on the respective sleep profiles and the target sleep outcome, determine one or more respective sleep adjustments for provision to at least one of the respective plurality of users, the respective sleep adjustments comprising stimuli configured to attempt to adjust a respective user's sleep during one or more of the respective user's sleep session and a subsequent sleep session, in an attempt to achieve, at least in part, the target sleep outcome of the plurality of users.

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract: To aid those with erectile disfunction, an anatomically erect penile prosthesis is disclosed that includes 1) an interior upper chamber that receives and houses the human penis, and 2) an interior lower chamber that receives and houses the human testicles. The prosthesis includes a flexible elongated member that provides a natural feeling substitute for the human penis that is contained within the interior upper chamber. The prosthesis includes an integral support mechanism that connects to the flexible elongated member to provide this natural feeling.

Abstract: The present invention provides apparatus and methods for artificial insemination or in-vitro fertilization for use with livestock that maintains the sterility of the semen or embryo(s) until deposited at an optimum location in the reproductive tract of the animal without the maneuvering or tissue injury problems associated with existing devices. The invention includes a uniquely shaped opening that is provided at the tip of a sheath that is used with an artificial insemination gun. A plug or diaphragm having a rounded (convex) exterior surface completely covers the opening at the tip of the sheath, and seals it closed in a smooth, flush engagement to prevent contaminants from collecting upon the tip, or entering into the sheath during the trip through the reproductive tract of the animal.

Abstract: The field of the disclosure relates generally to cancer cell destruction and, more specifically, to cancer cell destruction by photo-magnetic irradiation mediated multimodal therapy using smart nanostructures.

Abstract: A penile sleeve device (PSD) that is an implantable subcutaneous penile shaft silicone rubber apparatus which has several functions such as to elongate, thicken, harden, straighten and custom shape a penis. The PSD has an elongated main component of stretchable elastic silicone elastomer into which an inner component of a much higher durometer silicone rubber material is positioned to provide the PSD with some rigidity. The main component is the only portion in contact with the penile shaft since the inner component resides within a pocket of the main component that is formed by two layers therein. The outside surface of these layers may include folds to assist in enhancing penile girth and lengthening. A penile stocking insert is also provided for increasing the length of the penis it is flaccid or erect state using an elongated tubular body constructed from an elastic material which applies a compressive force around the penile shaft, thus elongating the length of the penis.

Abstract: Stimulation devices and methods of use are described herein. An example stimulation device configured to stimulate a portion of a body of a user comprises a housing that includes a casing and a covering. The casing includes a nozzle, a motor disposed within the casing configured to generate stimulation patterns, a drive shaft connected to the motor, a sensor configured to detect changes in the rotation of the draft shaft, a controller, and a battery. The covering covers a portion of the casing.

Abstract: An information processing apparatus includes a calculation unit, a designing unit, and a presentation unit. The calculation unit calculates autonomic activity of a participant, using biometric information measured by a measuring device that measures biometric information of the participant belonging to a group place. The designing unit designs a progress plan of communication at the group place in a design aspect corresponding to the calculated activity. The presentation unit presents the designed progress plan.

Abstract: A wirelessly powered inflatable medical implant system includes a medical provider software application, a patient external controller and a MR-Conditional, nonferrous pump in reservoir implant. The medical provider software application programs the patient external controller for the patient to transmit wireless power and control signals to circuitry in a pump in reservoir implant. In response, the pump in reservoir implant, containing a fluid reservoir and pump package submerged therein, transfers fluid from the reservoir through tubing, and into one or more inflatable medical implants. Submerging the pump package within the reservoir simplifies surgery in males and pump placement in females and provides pump package heatsinking to limit implant overheating.

Abstract: A penile sleeve device (PSD) that is an implantable subcutaneous penile shaft silicone rubber apparatus which has several functions such as to elongate, thicken, harden, straighten and custom shape a penis. The PSD has an elongated main component of stretchable elastic silicone elastomer into which an inner component of a much higher durometer silicone rubber material is positioned to provide the PSD with some rigidity. The main component is the only portion in contact with the penile shaft since the inner component resides within a pocket of the main component that is formed by two layers therein. The outside surface of these layers may include folds to assist in enhancing penile girth and lengthening. A penile stocking insert is also provided for increasing the length of the penis it is flaccid or erect state using an elongated tubular body constructed from an elastic material which applies a compressive force around the penile shaft, thus elongating the length of the penis.

Abstract: A method of lowering the blood lactate concentration of subject in the need thereof includes the step of applying to the subject a pulsating magnetic field to the thyroid area of the subject.

Abstract: Methods and devices for measuring vibration of an implanted driven vibrating elongate body coupled to a bone of the middle ear, for example using an accelerometer coupled to the vibrating body. The measured vibration can be taken during implantation and long again after implantation to check for possible decoupling, disease, or additionally impeded vibratory driving of the middle ear bone. An accelerometer signal can be converted to a displacement value and used to check for an under impeded or over impeded vibratory body. An implanted device can be used to periodically check the vibration of the vibratory body. Methods and devices can be used in conjunction with implanted devices which receive vibratory signals from a middle ear bone and use the signals to drive a disarticulated middle ear bone closer to the ear drum.

Abstract: The present invention relates to compositions and methods configured to deliver a stimulus (e.g., a therapeutic agent or a therapeutically beneficial signal) to a cell, tissue, organ, or organism. The stimulus is applied at least twice, and the first and second applications are separated by a rest period in which no further stimulus is actively applied. The rest period is of a duration (e.g., about 1-6 hours) sufficient to provoke an enhanced response to the second stimulus.

Abstract: Systems and methods for magnetic induction of a penile prosthesis are disclosed. The magnetic induction system includes a wand that has a coil arrangement covered with a thermal and electrical insulator sheath operable to generate an alternating magnetic field. The coil arrangement of the sheath is configured to receive the length of the penile prosthesis therein. The penile prosthesis may be made from a shape memory material such that application of alternating magnetic fields generated by the magnetic induction system induces eddy currents that raise the temperature of the penile prosthesis to a temperature above the austenitic transformation temperature that allows the penile prosthesis to achieve an erect state.