Abstract: A method for performing image-guided embryo transfer for in vitro fertilization includes performing a pre-operative magnetic resonance imaging (MRI) scan of a subjects pelvic region to yield a first MRI image dataset. A computer applies a segmentation routine to the first MRI image dataset to yield segment data which is then used by the computer to create an anatomical model of the subjects pelvic region. The computer determines an optimal implant location based on the anatomical model and creates a three-dimensional rendering of the optimal implant location based on the first MRI image dataset.

Abstract: Provided is an endoscope system capable of improving luminance and an S/N ratio of a normal observation image that is obtained in a special observation mode. In a special observation mode, after first illumination light is radiated, some of a plurality of pixel rows of an imaging element are reset en bloc. Illumination light is switched to second illumination light, the second illumination light is radiated, and then, a turned-off state is reached. During this turn-off period, signal reading is sequentially performed from all pixel rows. An image processing unit generates a normal observation image on the basis of a first imaging signal without being subjected to resetting. Further, the image processing unit generates an oxygen saturation image on the basis of a second imaging signal read from the pixel row subjected to the resetting and exposed by only the second illumination light, and the first imaging signal.

Abstract: The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.

Abstract: Thermography of an ablation site is carried out by navigating a probe into contact with target tissue in the heart, obtaining a first position of a position sensor in the probe and acquiring a first magnetic resonance thermometry image of the target tissue. The method is further carried out during ablation by iteratively reading the position sensor to obtain second positions, and acquiring a new magnetic resonance thermometry image of the target tissue when the distance between the first position and one of the second positions is less than a predetermined distance. The images are analyzed to determine the temperature of the target tissue.

Abstract: Devices, systems, and methods of imaging a blood vessel are provided. For example, the method can include obtaining fluoroscopic image data of a region of interest in a blood vessel using an x-ray source; obtaining intravascular ultrasound (IVUS) data at a plurality of positions across the region of interest using an IVUS component disposed on an intravascular device; processing the fluoroscopic image data and IVUS data, including: determining, using the fluoroscopic image data, a position of the intravascular device with respect to the x-ray source at each of the plurality of positions across the region of interest; co-registering the fluoroscopic image data and the IVUS image data; and generating, a model of the region of interest including position information of a border of a lumen of the blood vessel at each of the plurality of locations; and outputting a visual representation of the model of the region of interest.

Abstract: Systems and methods for planning and performing image free implant revision surgery are discussed. For example, a method for generating a revision plan can include collecting pre-defined parameters characterizing a target bone, generating a 3D model, collecting a plurality of surface points, and generating a reshaped 3D model. Generating the 3D model of the target bone can be based on a first portion of the pre-defined parameters. Generating the reshaped 3D model can be done based on the plurality of surface points collected from a portion of the surface of the target bone.

Abstract: A spectrally encoded imaging device having a light transmission path arrangement which propagates light to illuminate a target object, a light collection path arrangement having a light collection waveguide which propagates a spectrally encoded portion of the light from the target object to a detector which forms an image of the target object accordingly, and a diffractive element which spectrally disperses at least one of the light and the spectrally encoded portion. The light transmission path arrangement and the light collection path arrangement are optically isolated from one another.

Abstract: An ultrasonic device includes a base, a plurality of ultrasonic transducer elements, and a reinforcing body. The base defines a plurality of openings arranged in an array form. The ultrasonic transducer elements are arranged respectively corresponding to the openings with a plurality of vibration films being respectively provided for the ultrasonic transducer elements. The reinforcing body is fixed to the base in an area between adjacent ones of the vibration films when viewed in a plan view along a thickness direction of the base. The reinforcing body has Young's modulus greater than Young's modulus of the base.

Abstract: Methods for quickly estimating apparent diffusion coefficient probability density functions (ADC PDFs) for each image voxel are provided using a “diffusion reproducibility evaluation and measurement” (DREAM) magnetic resonance sequence. Non-diffusion-weighted (reference) images collected simultaneously have blood oxygenation level dependent (BOLD) sensitivity that can be used for resting-state fMRI data to measure functional connectivity, an unbiased parameter reflecting neurological integrity. ADC coefficient of variation (ADC CV) measurements can be used to isolate and label regions of non-enhancing tumor and predict future enhancement independent of FLAIR, T2, or average ADC maps. Functional diffusion mapping (fDMs) using voxel-wise changes in ADC PDFs can be used to spatially visualize and statistically quantify response to treatment.

Abstract: The invention relates to a tissue monitoring apparatus, a tissue monitoring method and an ablation lesion monitoring, measuring, and controlling automated algorithm incorporating diffuse reflectance spectroscopy (DRS) and/or Arrhenius model thermal denaturation kinetics for determining the characteristics of the lesion or the tissue, especially for identifying the transmurality of the ablation lesion. The invention pertains to a device for and method of real time monitoring of lesion formation as ablation is being carried out.

Abstract: A system and method for the use of the results from a structural analysis of a patient's bone from a clinical scan, to be used clinically to manage patients in a widespread and consistent fashion.

Abstract: A structured-light imaging system includes a structured light projector for illuminating a surface and an electronic camera configured to image the surface. An image processor receives the images and has structured light scatteroscopy (SLS) firmware with machine readable instructions that illuminate the surface with structured light having a spatial frequency of at least 0.5 mm?1, and process the images to determine a map of scattering parameters at the surface independent of absorption properties. In an embodiment, the system also has cameras configured to obtain a stereo pair of images of the surface, the image processor having 3D firmware for extracting a three dimensional model of the surface from the stereo pair of images and compensating the map for non-flat surfaces.

Abstract: Rather than rely on variation from physician to physician and limited imaging information for assessing plaque vulnerability of a patient, medical imaging and other information are used by a machine-implemented classifier to predict plaque rupture. Anatomical, morphological, hemodynamic, and biochemical features are used in combination to classify plaque.

Abstract: During a focused-ultrasound or other non-invasive treatment procedure, the motion of the treatment target or other object(s) of interest can be tracked in real time based on (i) the comparison of treatment images against a reference library of images that have been acquired prior to treatment for the anticipated range of motion and have been processed to identify the location of the target or other object(s) therein and (ii) complementary information associated with the stage of the target motion during treatment.

Abstract: The ultrasonic endoscope includes: an insertion part that includes a tip, a base end, and a longitudinal axis; an ultrasonic transducer that is provided at the tip of the insertion part; a locking groove that is a balloon mounting portion which is disposed closer to the base end of the insertion part than the ultrasonic transducer is and on which a balloon wrapping the ultrasonic transducer is detachably mounted; a balloon pipe line that extends in the insertion part; a tip-side opening surface of the balloon pipe line that is provided closer to the tip than the locking groove and has components normal to a direction of the longitudinal axis; and a groove portion which is formed toward the tip from the tip-side opening surface as a starting point and of which at least a part overlaps the ultrasonic transducer in the direction of the longitudinal axis.

Abstract: Ultrasound systems and methods provide a workflow to automatically identify a fetal heartbeat. A region of interest (ROI) is identified in an ultrasound image and an ROI icon is positioned around or over a fetal pole and/or fetal heart. The ultrasound system produces spatially different M-mode lines associated with the ROI icon. The ultrasound system can identify a fetal heartbeat and estimate the fetal heart rate from echo signals received from echo signals associated with at least one of the spatially different M-mode lines. The echo signals for the M-mode lines can also be ranked according to the likely presence of a fetal heartbeat in the echo data.

Abstract: An X-ray diagnostic apparatus according to this embodiment includes: a memory circuitry configured to store a program; and a processing circuitry configured to read the program from the memory circuitry, and execute the program, wherein the processing circuitry is configured to identify a predetermined three-dimensional region of a patient at a predetermined position based on multiple X-ray images taken in at least two directions, and adjust an X-ray irradiation range based on the identified three-dimensional region and on system position information that includes irradiation position information where the patient is irradiated.

Abstract: Systems and methods related to the location of target regions in imaging applications are generally described. Certain embodiments relate to devices and/or methods for image-guided identification of suitable regions at which to insert needles, catheters, and the like. Such systems and methods can be used in association with a variety of imaging technologies, including ultrasound imaging. In certain embodiments, the systems and methods described herein can be used in association with hand-held ultrasound imaging devices.

Abstract: Enhanced targeting systems and methods may be used to visualize trajectories for surgical instruments. Such a targeting system may have a first light source and a second light source. The first light source may project first light along a first plane, and the second light source may project second light along a second plane nonparallel to the first plane. At an intersection of the first and second planes, the first light and the second light may cooperate to produce a targeting line that indicates the desired trajectory. An image capture system may also be used to capture image data of anatomical features of a patient at one or more locations in space, and a controller may receive the image data and indicate the trajectory relative to the anatomical features of the patient.

Abstract: A method for obtaining a 3-D OR-PAM image of microvasculature within a region of interest of a subject is provided. The method includes: focusing a first light pulse at a first depth beneath a first surface position within the region of interest; receiving a first PA signal in response to the first light pulse; focusing a second light pulse at a second depth beneath the first surface position within the region of interest; receiving a second PA signal in response to the second light pulse; and forming the 3-D OR-PAM image by combining the first PA signal and the second PA signal.