Abstract: A hydrogen-generating substance that reacts with moisture (liquid water or water vapor) in a medical substance or moisture in air introduced into a medical container is kneaded into an exterior sheet 40 of the medical container that encloses the medical substance therein. The medical container can be a bag-shaped medical container, a tube-shaped medical container, a medical container with a sealing fastener or the like. The medical substance containing moisture can be blood, an injection solution, a drug solution, a nutrient solution, a replenishment solution (an infusion solution), an instillation solution or the like. A solid preparation is preferably enclosed within the medical container with the sealing fastener. For example, the hydrogen-generating substance to be kneaded can be metal magnesium and is preferably fine-powdered ceramics obtained by firing the mixture of a hydrogen-generating substance and a mineral substance such as calcium.

Abstract: Method and apparatus for removing high density particles from a biological fluid such as blood using aphaeresis. The particles are preferably sub-micron in size and denser than normally occurring components of the fluid and can be removed by a modified reverse-flow gradient density centrifuge without damaging the fluid. The particles can be provided to a patient in vivo or added to the fluid after it is removed from the patient. Some particles can carry and deliver oxygen and scavenge carbon dioxide. Other particles are conjugated to capture molecules for attaching to targets such as cancer cells, viruses, pathogens, toxins, or excess concentrations of a drug or element in the fluid. The targets are then removed from the fluid along with the particles by the aphaeresis instrument.

Abstract: The disclosure provides an applicator for applying a cosmetic treatment product to the skin or the lips, the applicator comprising at least: an application portion comprising a bundle of needles for applying the cosmetic treatment product and extending along a longitudinal axis, the bundle of needles comprising at least one first set of needles having a distribution that is square in cross-section relative to the longitudinal axis; and a linear drive device connected to the application portion and configured to constrain the bundle of needles to perform reciprocating motion along the longitudinal axis.

Abstract: Methods, dressings, and systems for promoting epithelialization of a wound or other tissue are presented. The methods, dressings, and systems help form simulated rete pegs. In one instance, an epithelialization dressing is disclosed that may include a dressing body having a plurality of projections. A plurality of apertures is formed on a portion of the dressing body. The dressing helps manage fluids on the wound and the projections form cavities into which epithelial tissue migrates to from epithelial columns that function like rete pegs. Other dressings, methods, and systems are disclosed.

Abstract: A disposable urine trap in the form of a foldable pad that envelops the male genitalia and closes around the organ to form a barrier that prevents urine from escaping the trap. The pad includes an asymmetric pair of wings that are separated by a gap and attached to the main body of the pad. The first wing is preferably rectangular in that the distal angles are substantially right angles with parallel side edges and a perpendicular distal edge, and has a length that exceeds a length of a second wing, which is terminates so that the distal edge of the second wing is angled to form an obtuse and an acute angle with respect to its generally parallel sides.

Abstract: This disclosure relates to methods of reversing blood flow using a blood flow reversal valve that includes a first member having a first passage and a second passage, and a second member having a first passage and a second passage. The first and second members are rotatably fixed relative to one another such that the first passage of the first member is aligned with the first passage of the second member and the second passage of the first member is aligned with the second passage of the second member. A flow directing element is disposed in the cavity and is moveable between a first position in which the first passage of the first member and the first passage of the second member are fluidly connected and a second position in which the first passage of the first member and the second passage of the second member are fluidly connected.

Abstract: A vacuum powered ‘pimple puller’ configured to extract pus and other biomaterial from within an individual's or animal's clogged pore with mild suction provided by an external vacuum source, which is channeled through the body of the present invention. The force of the vacuum is focused on the target area of skin by one of a variety of applicator tips designed to be affixed to the head of the present invention while in use. It is the intent of the present invention to successfully remove biomaterial from a pore by rupturing the skin's surface, while minimizing the risk of infection.

Abstract: A connector system for medical fluid administration has a female connection member, which can act as an access port for a container of medical fluid, and a male connection member, for accessing the container of medical fluid. The female connection member defines a sheath for receiving a portion of the male connection member and this sheath is spanned at one end by a septum, which acts to close the container of medical fluid. A lumen is defined through the male connection member to allow passage of fluid therethrough. The septum has a central region and a peripheral region, the central region being of substantially greater thickness than the peripheral region. The male connection member comprises means for rupturing the peripheral region of the septum when it is received in the female connection member to form a connection.

Abstract: To provide a solution applicator with which irritation on an affected part of a patient may be reduced even when a solution is used. According to the present invention, an applicator comprises a solution container which comprises an opening, and a columnar brush member formed by bundling synthetic fibers in a columnar shape. The columnar brush member is disposed at the opening of the solution container, a tip portion of the columnar brush member at an outside of the solution container has a fan shape expanding in a perpendicular lateral direction against a pillar axial lengthwise direction, and a thickness of the fan-shaped tip portion of the columnar brush member decreases in a perpendicular lengthwise direction against the pillar axial lengthwise direction toward the tip portion of the columnar brush member.

Abstract: A toroidal compression bandage includes: a soft fibrous material, defined by an absorbency of a predetermined amount; a compression bandage form comprised of soft fibrous absorbent material in a rolled, wrapped form and of a shape defined by a circle revolved in three-dimensional space about a circular axis coplanar with the circle, wherein the axis of revolution does not touch the rotated circle, to define a torus ring compression bandage; an aperture defined within a center area of the torus ring compression bandage as it is formed, the aperture having a predetermined diameter and configured for placement directly over a trauma wound to avoid contact with the trauma wound; and a compression surface defined on an underside of the torus ring compression bandage, the compression surface configured for circumferential placement around the trauma wound to avoid direct contact of the trauma wound, and for absorption placement around the trauma wound.

Abstract: Systems, devices, and methods for treating a tissue site on a patient with reduced pressure are presented. In one instance, a reduced-pressure treatment device to treat a tissue site with reduced pressure may include a pump control unit fluidly separate from a collection unit. Pump energy may be provided by the pump control unit to deflect one or more diaphragms within the collection unit to create reduced pressure. Other systems, devices, and methods are presented.

Abstract: A controller is operable to selectively supply gas to, and evacuate gas from, regions of a hyperbaric wound treatment chamber. The controller operates to inflate a passage or rib of the device to provide that the device is made sufficiently rigid for inserting a limb therethrough, and inflate an inflatable cuff to create a seal against the limb. The controller also operates to evacuate ambient air trapped within the chamber, and optionally partially evacuate the passage or rib, after the seal is created by the inflatable cuff, and then introduce oxygen into the chamber, and optionally inflate the passage or rib. The cuff, when inflated and creating a seal against a limb, optionally is at least partially within the chamber, and the treatment gas is supplied to the chamber to maintain the seal of the cuff against the limb.

Abstract: An apparatus for promoting the healing of an exuding wound includes a cover layer for positioning over a wound to define a reservoir over the wound. An exudate conduit having a fibrous core includes a plurality of fibers communicates with the reservoir for wicking fluids away from the wound.

Abstract: A rectal drainage appliance is disclosed comprising a tubular element having an inflatable balloon at a distal end for anchoring the appliance in the rectum. The appliance includes one or more of: (i) first and second auxiliary lumens communicating with the inflatable balloon to provide independent inflation and pressure monitoring paths coupled to the balloon; (ii) a pressure state indicator defined by a mechanical element configured to flip between first and second states or shapes responsive to sensed pressure; and (iii) a collapsible auxiliary lumen larger than the inflation lumen, and configured to permit admission of irrigation fluid. The pressure state indicator may also be used in intestinal drains.

Abstract: Reduced-pressure treatment systems and methods are disclosed that employ debridement mechanisms to remove unwanted tissue. In one instance, a reduced-pressure treatment system for treating a tissue site on a patient includes a manifold member for distributing reduced pressure to the tissue site, a support member for disposing proximate the tissue site and the manifold, and a debridement mechanism coupled to the support member. The debridement mechanism is for debriding the tissue site. The system further includes a sealing drape for placing over the tissue site and manifold member. The sealing drape is operable to form a fluid seal over the tissue site and manifold member. The system also includes a reduced-pressure subsystem for delivering a reduced pressure to the sealing drape. The system may further include a chemical-debridement subsystem. Other systems, manifolds, and methods are disclosed.

Abstract: The present invention is an improved applicator comprising an applicator body having a top portion, a bottom portion and a central portion, a bladder positioned between the bottom portion and the central portion of the applicator body and designed for holding alcohol solution, a hinge lever extending from an inner side of the central portion and extending outwards from the top portion of the applicator body and a hinge door positioned on the central portion of the applicator body. The cartridge of swabs can be easily loaded by opening the hinge door and rests between the bottom portion and the central portion of the applicator body. The used swabs can be easily discarded by clicking the hinge lever. The improved applicator allows easy application of alcohol solution to the patient's skin in a simple and safe manner and provides a safe and convenient hand-held method for safe preparation of skin.

Abstract: Several gastrointestinal surgery procedures are effective as treatments for metabolic disorders such as obesity and diabetes. Minimally invasive procedures including intra-luminal gastrointestinal implants have been proposed to mimic the anatomical, physiological and metabolic changes achieved by these procedures. Many of these designs include long sleeve like elements that prevent contact of food with the walls of the small intestine. It is desirable to have simple delivery systems that can place these implants under endoscopic guidance. However, in order to anchor these sleeve elements safely and reliably, the inventors have previously disclosed anchoring means that anchor the sleeves at the junctions of the stomach and the intestine or the stomach and esophagus.

Abstract: The present disclosure provides a portable drug dispenser which includes one or more chambers for holding a plurality of separately contained drug products, a dispensing mechanism for accurately dispensing one or more of the plurality of separately contained drugs upon activation of the dispensing mechanism in a specified dose (e.g. specified volume/number of drops) at specified times, and a processor configured to determine the time, and potentially other information such as, e.g. location, patient variables, user data input of each activation of the dispensing mechanism, and an ability to transmit the determined time of activation to a computer located remote to the dispenser, optionally stored on the device as well for read out by a clinician managing the patient.

Abstract: Embodiments of the invention are directed to apparatuses and kits for providing palliative care. An exemplary apparatus comprises an elongate hollow shaft having a first and a second end. An absorbent material may be attached to the first end and the first end may be perforated such that the elongate hollow shaft may be filled with one or more liquid solutions that flow through the perforated end and disperse evenly throughout the absorbent material. A kit may additionally be provided for providing customized palliative care. The kit may comprise a means for injecting one or more liquid solutions into the elongate shaft. The kit may additionally comprise apparatuses that are prefilled with one or more liquid solutions.

Abstract: A male surface fastener has a sheet having a main surface, and a group of engagement elements in which the engagement elements are regularly arranged, the engagement element having a pillar that stands on the main surface of the sheet and an engagement head that is expanded along the main surface from the top end of the pillar, wherein 0.05?S2/S1?0.15 is satisfied where S1 represents an area of the main surface which corresponds to a region in which the group of engagement elements is arranged, and S2 represents a sum of areas of the top surfaces of the engagement heads of the engagement elements of the group of engagement elements.