Abstract: A surgical clip applier is provided including a channel assembly and overlying a clip carrier having a clip counter plate slidably supported in the channel assembly, wherein the clip counter plate is configured and adapted to display a change in status of the clip applier upon actuation of the handle.

Abstract: The present disclosure describes a subcutaneous cutting device for insertion into tissues and cutting of targeted tissues. The cutting device includes a handle, a cannula extending distally from the handle to a sharpened distal tip, and an adjustable blade disposed within a blade-holding section of the cannula. The blade is selectively adjustable between a retracted position within the cannula and an open position with the blade tip lifted up and angled away from the cannula. When the blade is in the open position, the blade tip points proximally toward the handle.

Abstract: An instrument with a motor drive assembly detachable from a handle assembly and detachable from a gear assembly, where the gear assembly is inside the handle assembly and further the instrument comprising a standard telescope which is detachable from the instrument and a cutter/blade assembly detachable from an outer sheath. In an aspect, an instrument (1) includes a motor drive assembly (2) that is detachable from a handle assembly (3) and detachable from a gear assembly (5), wherein the gear assembly (5) is positioned inside the handle assembly (3), and wherein the motor drive assembly (2) is detachable for the purpose of being reused after cleaning or its replacement.

Abstract: An apparatus and method for minimally invasive suturing is disclosed. A suturing device for minimally invasive suturing includes proximal section having a proximal end, a distal end, and a longitudinal axis therebetween; a suture head assembly extending from the distal end of the proximal section; a suturing needle having a pointed end and a blunt end, the suturing needle capable of rotating about an axis approximately perpendicular to a longitudinal axis of the proximal section, wherein the pointed end of the suturing needle is positioned within the suture head assembly prior to and after rotation of the suturing needle; and an actuator extending from the proximal end of the proximal section to actuate a drive mechanism having a needle driver for engaging and rotating the suturing needle.

Abstract: Embodiments of a knot pusher and methods of use thereof are disclosed, that are usable for pushing a knot formed from a suture, two limbs of the suture extending from the knot. The knot pusher comprises a distal head defining top and bottom walls terminating in a distal knot pushing surface. The distal head includes at least two side grooves defined between the top and bottom walls that extend proximally from the knot pushing surface. Each of these side grooves is operable to receive one of the limbs of suture. The distal head additionally comprises at least one suture guide coupled to the top and bottom walls for guiding the one of the limbs of suture into one of the side grooves.

Abstract: Various embodiments for a stent delivery device that utilizes a first mode of actuation for slow retraction of an outer sheath and a second mode of actuation for fast retraction of the outer sheath during delivery of a self-expanding implantable device such as a stent or stent graft.

Abstract: In some embodiments, an insertion device for a robotic surgery apparatus can include one or more guides configured to receive and/or engage a plurality of control links. The one or more guides can each include a plurality of channels. The insertion device can include a tool interface configured to engage one or more surgical tools for performing a surgical procedure. At least one control link of the first, second, or third pluralities of control links can be overlapping, coaxially aligned, or otherwise placed in a nested configuration with respect to another control link of the first, second, or third pluralities of control links. One or more of the plurality of first, second, or third control links can be configured to be actuated to adjust spatial position of the tool interface to facilitate repositioning of the surgical tool.

Abstract: Systems and methods for replacing a native heart valve. An anchor comprises multiple coils adapted to support a heart valve prosthesis. At least one of the coils is normally at a first diameter, and is expandable to a second, larger diameter upon application of radial outward force from within the anchor. An expansible heart valve prosthesis is provided and is configured to be delivered into the anchor and expanded inside the multiple coils. This moves at least one coil from the first diameter to the second diameter while securing the anchor and the heart valve prosthesis relative to each other. The system further includes a seal on the anchor that can prevent at least some blood leakage after implantation of the heart valve prosthesis in the helical anchor. Additional apparatus and methods are disclosed.

Abstract: The invention relates to an implant for vascular applications that can be transported by means of a catheter and is intended in particular to influence the blood flow in the area of arteriovenous malformations, such as fistulas and aneurysms, to fill the saclike dilation of the malformation, promote thrombus formation and cover the neck of the malformation. The implant according to the invention is provided with an occlusion unit (1, 13) having a three-dimensional shape constructed from several subunits (5a, 14) from a framework of struts (5, 16, 17), with a covering, preferably a membrane (6), being located between struts (5, 16, 17).

Abstract: Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Deployment systems and methods for using the deployment systems described herein facilitate implanting a two-part prosthetic heart valve that is arranged in a nested configuration during the transcatheter delivery and deployment processes.

Abstract: The devices and methods described herein relate to improved structures for removing obstructions from body lumens. Such devices have applicability in through-out the body, including clearing of blockages within the vasculature, by addressing the frictional resistance on the obstruction prior to attempting to translate and/or mobilize the obstruction within the body lumen.

Abstract: A left atrial appendage occluder and a fabricating method thereof are provided. The left atrial appendage occluder includes a plugging column and a anchor located on the plugging column, wherein the plugging column is woven from an elastic metal wire, or woven from an elastic metal wire and an elastic metal sheet, the anchor is made by partially flattening and then cutting the elastic metal wire, or the anchor is made by cutting the elastic metal sheet. In the above-described left atrial appendage occluder, firstly, the anchor is formed on the elastic metal wire and/or the elastic metal sheet, and then the elastic metal wire and/or the elastic metal sheet with the anchor are/is co-woven with other elastic metal wire to form the plugging column of the left atrial appendage occluder. Therefore, the amount of the anchor is not limited, and a plurality of anchors can be provided.

Abstract: A cutting device is provided having multiple evenly-spaced cutting blades and which is useful for producing tissue forms comprising membranous tissue fragments which are relatively uniformly sized and shaped. The present invention also relates to methods for using the cutter device to quickly and efficiently produce such tissue forms which are useful as grafts and can be flowable and easily passable through a luer-slip tip syringe or needle.

Abstract: In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.

Abstract: A surgical clamp jaw is disclosed, having an inner profile and a deflection control profile opposite the inner profile. In one embodiment, the inner profile has a first substantially concave profile in an unclamped position and a second substantially flat profile in a clamped position. In one embodiment, the deflection control profile has one or more sets of corresponding abutment surfaces, at least one set of which is not contacting each other when the inner profile is in the unclamped position and which is contacting each other when the inner profile is in the clamped position. In one embodiment, the surgical clamp jaw defines one or more flexion assistance voids, wherein at least one of the one or more flexion assistance voids is in contact with a gap between one of the one or more sets of corresponding abutment surfaces.

Abstract: An endoscopic stone-extraction device is provided comprising a support filament comprising an end portion having a plurality of stacked loops, a sheath comprising a lumen, wherein the support filament is disposed in the lumen such that the sheath is slideable with respect to the support filament, and a handle comprising an actuator. Movement of the actuator in a first direction retracts the sheath and causes the plurality of stacked loops to expand outside the lumen in an arc-like shape. Movement of the actuator in a second direction advances the sheath and causes the plurality of stacked loops to at least partially collapse inside the lumen. Other embodiments are provides, and any of these embodiments can be used alone or in combination.

Abstract: Instruments for placing complex sutures into animal tissues, including instruments useful in arthroscopic surgical techniques which minimize incision size. Manipulate the flat tissue by, for example, rolling, wrinkling, folding, bending or tucking the tissue so that a needle can be placed through the tissue more than once. Sutures are placed, for example from top-to-bottom and bottom-to-top with a single pass of a straight needle. Roll, wrinkle, fold, bend or tuck the flat tissue so that a needle can be placed through the tissue more than once. Suturing a loop through the tissue that another suture will pass through result in sewing both sides of the tissue. This will allow surgeons to place complex locking and grasping suture configurations that will significantly improve the repair.

Abstract: A tissue resecting end effector includes a housing, a shaft extending from the housing, and a drive assembly operably coupled to the shaft such that a rotational input provided to the drive assembly effects the rotation and reciprocation of the shaft relative to the housing. The assembly includes a proximal portion translationally fixed and rotatably coupled to the housing and configured to receive the rotational input and to rotate relative to the housing in response thereto, a distal portion translationally and rotatably coupled to the housing and operably coupled to the proximal portion such that the rotation of the proximal portion relative to the housing effects rotation and reciprocation of the distal portion relative to the housing to thereby rotate and reciprocate the first shaft relative to the housing, and a seal member disposed on the proximal portion or the distal portion and configured to selectively establish a seal therebetween.

Abstract: In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.

Abstract: A system for creating an endoluminal valve from a blood vessel wall, includes: a tubular assembly having a longitudinal axis, a proximal end, a distal portion with a distal end, and a first lumen extending from the proximal end to a distal port located proximate the distal portion, the distal port located along the longitudinal axis, the distal portion having a supporting surface on a same side of the tubular assembly as the distal port, the supporting surface extending in a longitudinal direction and offset from a surface of the tubular assembly proximal the distal port and configured to contact the blood vessel wall; and a tissue dissection probe disposed within the first lumen, the tissue dissection probe having a fluid delivery lumen extending to a fluid delivery port located at a distal end of the tissue dissection probe, the tissue dissection probe configured to be inserted into the blood vessel wall.