Patents Examined by Sarah Al-Awadi
  • Patent number: 8007831
    Abstract: A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: August 30, 2011
    Assignee: Biocompatibles UK Limited
    Inventors: Andrew Lennard Lewis, Yiqing Tang, Maria Victoria Gonzalez Fajardo
  • Patent number: 7976865
    Abstract: A medical tape preparation which comprises a support and, superposed on one side thereof in the following order, a pressure-sensitive adhesive layer and a release liner. The pressure-sensitive adhesive layer can contain a large amount of an oleophilic oily matter. The tape preparation is excellent in adhesion, cohesiveness, and stability even when no crosslinking agent is used. The pressure-sensitive adhesive layer in the medical tape preparation comprises a blend of two tacky polymers, which are a tacky polymer (A) comprising a copolymer obtained from 2-acetoacetoxyethyl methacrylate and other vinyl monomer(s) as constituent ingredients and a tacky polymer (B) comprising a copolymer which is obtained from a C4-10-alkyl (meth)acrylate and other vinyl monomer(s) as constituent ingredients and is different from the tacky polymer (A).
    Type: Grant
    Filed: December 12, 2005
    Date of Patent: July 12, 2011
    Assignee: Nipro Patch Co., Ltd.
    Inventors: Naohisa Kawamura, Hidenori Sawada, Takayuki Kobayashi
  • Patent number: 7964209
    Abstract: The present invention provides a method for the formation of a medical device that comprises a therapeutic agent and a release region, which regulates the rate at which the therapeutic agent is released from the medical device. The method comprises providing a precursor region that comprises a polymer composition comprising two or more microphase separated polymer domains that are immiscible with one another, and forming said release region by a process that comprises applying an orienting field comprising an electric field, a magnetic field, a mechanical shear field, or a solvent gradient field, or a combination of two or more fields to said precursor region, wherein said field or combination of fields changes the spatial orientation of the microphase separated polymer domains within the release region. The electric, magnetic, mechanical shear or solvent gradient field is of sufficient strength to change the spatial orientation of the microphase separated domains.
    Type: Grant
    Filed: December 7, 2004
    Date of Patent: June 21, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Shrirang V. Ranade, Robert E. Richard, Kinh-Luan (Lenny) D. Dao, Samuel P. Gido, Akinbode Idowu Isaacs-Sodeye
  • Patent number: 7959948
    Abstract: A pharmaceutical composition comprising (i) quetiapine or a pharmaceutically acceptable salt thereof, especially quetiapine fumarate; (ii) a mixed excipient comprising an intimate admixture of polyvinylacetate and polyvinylpyrrolidone in a weight ratio from 5:2 to 10:2; and, optionally (iii) an acid especially fumaric acid.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: June 14, 2011
    Assignee: Synthon BV
    Inventor: Korinde Annemarie Jansen
  • Patent number: 7959905
    Abstract: A dermatological composition which may be used for the topical treatment of the skin, hair, or nails of mammals, comprising tamanu oil, an unsaturated fatty acid, and arnica oil, optionally including Vitamins E and A. The dermatological composition may be combined with other components to form a shampoo, conditioner, lotion, cream, spray, salve, or other cosmetic product in liquid, paste, or powder form.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: June 14, 2011
    Assignee: T.F.H. Publications, Inc.
    Inventors: Glen S. Axelrod, Ajay Gajria
  • Patent number: 7947258
    Abstract: An aqueous hair cleansing agent containing the following components (A), (B) and (C): (A): an anionic surfactant; (B): a cationized tara gum; and (C): an amino-modified silicone represented by a specific formula.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: May 24, 2011
    Assignee: Kao Corporation
    Inventor: Eiji Terada
  • Patent number: 7923026
    Abstract: The present invention relates to a thermostable solid composition containing nanosized micelles, the micelles containing a poorly soluble chemical substance, such as a biologically active substance, dissolved in an auxiliary material, and the micelles being embedded in a water soluble carrier. The invention further relates to a process for preparing a thermostable solid composition and to a process for preparing pharmaceutical dosage forms comprising the same.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: April 12, 2011
    Assignee: Solvay Pharmaceuticals B.V.
    Inventor: Jan Peter Möschwitzer
  • Patent number: 7914776
    Abstract: Solid dispersions of stable, amorphous opioid antagonists, particularly [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid, with improved water solubility and bioavailability are disclosed. Also disclosed are methods of preventing or treating a side effect associated with an opioid. In addition, methods of treating or preventing pain, ileus, and opioid bowel dysfunction are disclosed.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: March 29, 2011
    Assignee: Adolor Corporation
    Inventor: Virendra Kumar
  • Patent number: 7871600
    Abstract: A leave on hair care composition comprising a) a wax dispersion; and b) an aqueous oil emulsion wherein the oil phase is a liquid and comprises: i) one or more non-volatile oils, where the dynamic viscosity of any single non-volatile oil or the dynamic viscosity of a blend of non-volatile oils is less than 1000 mPa·s at 35° C. and 5 s-1; ii) an oil dispersible structurant such that the dynamic viscosity of the structured oil phase at 35° C. prior to formation of the emulsion is at least 50,000 mPa·s at a shear rate of 0.5 s-1 and is less than 6,000 mPa·s at a shear rate of 500 s-1.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: January 18, 2011
    Assignee: Conopco Inc.
    Inventors: Takahiro Hiraishi, Stuart Keith Pratley, Aart van Vuure
  • Patent number: 7871643
    Abstract: A pharmaceutical form, contains an active compound-containing core, which is covered with a coating layer of a gastric juice-resistant, intestinal juice-soluble (meth)acrylate copolymer, a separating layer situated between said core and said coating layer, the separating layer containing a film-forming water-soluble polymer, wherein the separating layer contains at least two layers: an inner layer containing a water-repellent substance, and thereon a layer comprising the film-forming water-soluble polymer.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: January 18, 2011
    Assignee: Evonik Roehm GmbH
    Inventors: Rosario Lizio, Erna Roth, Hans-Ulrich Petereit
  • Patent number: 7862830
    Abstract: The present invention relates to a composition of a first single enantiomer homopolymer and a separate stereocomplex formed of a second single enantiomer homopolymer and it mirror image enantiomer, wherein the first and second single enantiomer homopolymers can be the same or different.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: January 4, 2011
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: David C. Gale, Syed Faiyaz Ahmed Hossainy, Bin Huang
  • Patent number: 7858109
    Abstract: Form bodies, which can be rotationally-symmetrical or irregularly-shaped, consist of at least one member of the group of the antibiotic salts, gentamicin myristate, gentamicin palmitate, gentamicin stearate, tobramycin myristate, tobramycin palmitate, tobramycin stearate, amikacin myristate, amikacin palmitate, amikacin stearate, vancomycin palmitate, vancomycin stearate, ramoplanin palmitate, ramoplanin stearate, levofloxacin palmitate, levofloxacin stearate, ofloxacin palmitate, ofloxacin stearate, moxifloxacin palmitate, moxifloxacin stearate, clindamycin palmitate, and clindamycin stearate. A medical device for implantation, in which the form bodies are arranged on a biodegradable filament at a distance of 1 mm to 25 mm as well as a method for the manufacture of the medical device and the use of the form bodies or the medical device to treat chronic osteomyelitis are described.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: December 28, 2010
    Assignee: Heraeus Kulzer GmbH
    Inventors: Klaus-Dieter Kühn, Sebastian Vogt
  • Patent number: 7851502
    Abstract: Pharmaceutical formulations are provided which are in the form of capsules or tablets for oral use and which include a medicament dapagliflozin or its propylene glycol hydrate and a pharmaceutical acceptable carrier therefor, which formulation is designed for immediate release.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: December 14, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Dilbir S. Bindra, Mandar V. Dali, Prakash V. Parab, Jatin M. Patel, Li Tao, Ravindra W. Tejwani, Nipa Vatsaraj, Yongmei Wu
  • Patent number: 7815927
    Abstract: Disclosed herein are implantable medical devices comprising controlled release terpolymers and at least one drug releasable from said terpolymers coating. The terpolymers of the present invention are comprised of acrylate and/or vinyl monomers.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: October 19, 2010
    Assignee: Medtronic Vascular, Inc.
    Inventors: Peiwen Cheng, Kishore Udipi, Mingfei Chen
  • Patent number: 7749528
    Abstract: A device for selective delivery of therapeutic agents to internal body tissues is disclosed. Upon tight sealing of the device to targeted tissues the diffusion of therapeutic agents to the targeted tissue can be controlled, while minimizing exposure of adjacent organs to the agents being delivered. Mechanisms for replenishment of the device and methods for application of the device in remote sites of the body are disclosed.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: July 6, 2010
    Inventors: Ricardo Azevedo Pontes De Carvalho, Alan Linn Murphree, Edward E. Schmitt
  • Patent number: 7709020
    Abstract: This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which: A is absent or is —O—, —S— or —NR2—; Q is absent or (if A is —O—, —S— or —NR2—) Q may be —V—, —OV—, —SV—, or —NR2V—, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR2VA; K is O or S; each occurrence of Y is independently —O—, —S—, —NR2—, or a bond linking a R5 moiety to P; each occurrence of R2 and R5 is independently an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, or H; and each occurrence of R6 is independently —PK(YR5)(YR5), —SO2(YR5) or —C(O)(YR5); so long as any R2, or R5 moiety linked directly to P is not H; wherein two R2, R5 and/or R6 moieties may be chemically linked to one another to form a ring; each occurrence of G is independently —O—, —S—, —NR2— or (M)x; each occurrence of M is independently a substituted or unsubstituted methylene moiety, and any M-M? moie
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: May 4, 2010
    Assignee: ARIAD Pharmaceuticals, Inc.
    Inventors: David L. Berstein, Leonard W. Rozamus, Yihan Wang, Chester A. Metcalf, III