Abstract: DQ beta gene oligonucleotides consisting essentially of the sequence GGCCGCCTGCCGCCGAG or of the sequence GCTGGGGCTGCCTGCCG and the use of such oligonucleotides in a method for assaying for a polymorphic region associated with Type I diabetes mellitus in humans.

Abstract: Repetitive DNA sequences of the protozoan parasites T. cruzi and P. falciparum have been isolated. These sequences appear more than once in the parasitic organism. Once isolated, the DNA sequences may be labelled with materials such as chromogens, biotin, or radioactive substances. The sequences may be used, in labelled or unlabelled form, as probes for the parasites.

Abstract: A method for sequencing nucleic acid polymers is provided in which the polymer to be sequenced acts as a template for the production of a complementary polymer by a polymerase enzyme. The template polymer is introduced into a polymerization environment in which production of the complementary polymer will occur if appropriate nucleotides are provided. The nucleotides are then provided to the polymerization environment one at a time in individual feedstocks. If the nucleotide in a feedstock is complementary to the next base in the template polymer, i.e., the unpaired base closest to the growing end of the complementary polymer, polymerization will occur lengthening the complementary polymer and releasing PPi. By separately recovering each feedstock and analyzing it for the presence of PPi, the sequence of the complementary polymer and thus the template polymer is determined.