Abstract: An implantable stimulator system includes a plastic housing, an electronic subassembly and at least one metal contact. The plastic housing defines an interior chamber and an exterior. The electronic subassembly is disposed in the interior chamber of the plastic housing. The at least one metal contact is integrally formed with the plastic housing, coupled to the electronic subassembly, and accessible from the exterior of the housing. The plastic housing and the at least one metal contact form a sealed structure around the electronic subassembly.

Abstract: A lead includes an elongated body and an anchor segment disposed between the distal end of the body and electrodes on a distal portion of the body. The anchor segment has lobes which are separated by slits and movable between a collapsed position and an expanded position. A positioning mechanism is disposed inside the hollow interior of the body and at least partially within the anchor segment. The positioning mechanism has a distal positioning portion attached to the distal end of the body and a proximal positioning portion. A control member is connected with the proximal positioning portion to control the positioning mechanism to pull the distal end toward the proximal end so as to move the lobes from the collapsed position to the expanded position and to push the distal end away from the proximal end so as to move the lobes from the expanded to the collapsed position.

Abstract: An external component of a cochlear implant system. The external component includes a support configured to house one or more electronic components and to be mounted to an outer ear of a recipient, and an external antenna configured to provide one or more of power and data signals from the electronic components to an implantable component of the cochlear implant system, wherein the external antenna is mounted to the support such that the external antenna moveable relative to at least a portion of the support.

Abstract: The present disclosure provides a medical device that includes a neurostimulator. The neurostimulator includes one or more channels. Each channel includes a digitally-controlled switch coupled to a voltage source. The switch is in one of an “on” state and an “off” state in response to a first control signal. Each channel also includes a digitally-controlled current sink coupled to the switch. The current sink is coupled between the switch and the voltage source. The current sink draws a variable amount of electrical current in response to a second control signal. Each channel further includes a conductor coupled to the switch and the current sink. The conductor is configured to be coupled to an electrode that is operable to deliver the electrical current drawn by the current sink to a target tissue area.

Abstract: A holding member for an implantable cardiac device facilitates tether attachment and removal, at time of implant, and snaring, or otherwise capturing, for subsequent explant. Preferably located in proximity to a proximal end wall of a shell of the device, the holding member includes a strut portion, being spaced proximally apart from the proximal end wall, a waist portion, defining a recess, and an engagement section, extending between the strut portion and the waist portion and overhanging the recess. The waist portion may either extend between the strut portion and the proximal end wall, or be formed in the shell, distal to the proximal end wall. Alternately, the holding member includes a loop element and an engagement element coupled thereto, between first and second segments thereof. The segments are initially formed to give the loop element an opening, and have a flexibility to be compressed together.

Abstract: An apparatus, a method, and a computer program for predicting a risk for a cardiac death are presented. Early repolarization patterns in leads of an electrocardiogram recorded from a subject are detected if an amplitude of a J-point at a QRS complex and ST segment junction of a lead exceeds a predetermined amplitude threshold. Amplitude patterns of ST segments in leads of the electrocardiogram are also determined. Finally, an elevated risk for a future cardiac death of the subject on the basis of a possible arrhythmia is predicted if early repolarization patterns are detected in at least two leads of the electrocardiogram, and if the ST segments in the at least two leads of the electrocardiogram are determined to have a horizontal or descending amplitude pattern.

Abstract: A cardiac rhythm management system includes an implantable device executing a dynamic pacing algorithm after an myocardial infarction (MI) event. The dynamic pacing algorithm dynamically adjusts one or more pacing parameters based on a person's gross physical activity level. Examples of the one or more pacing parameters include atrioventricular pacing delays and pacing channels/sites. The dynamic pacing algorithm provides for improved hemodynamic performance when a person's metabolic need is high, and post MI remodeling control when the person's metabolic need is low.

Abstract: Systems and methods using a heart valve and an implantable medical device, such as for event detection and optimization of cardiac output. The cardiac management system includes a heart valve, having a physiological sensor. The physiological sensor is adapted to measure at least one of an intrinsic electrical cardiac parameter, a hemodynamic parameter or the like. The system further includes an implantable electronics unit, such as a cardiac rhythm management unit, coupled to the physiological sensor of the heart valve to receive physiological information. The electronics unit is adapted to use the received physiological information to control delivery of an electrical output to the subject.

Abstract: Provided is a neural device including at least one nano-wire. The neural device includes a nano-wire formed on a base formed on a first surface of a substrate, and an electrode pad formed on a second surface different from the first surface of the substrate and configured to output an electrical signal gained from a neural fiber through the nano-wire or apply a signal for an electric stimulus to the nano-wire. Therefore, it is possible to prevent the nano-wire from becoming embedded in an encapsulation and maximize a contact between the nano-wire and a nerve.

Abstract: An apparatus and method for stimulating animal tissue (for example to trigger a nerve action potential (NAP) signal in a human patient) by application of both electrical and optical signals for treatment and diagnosis purposes. The application of an electrical signal before or simultaneously to the application of a NAP-triggering optical signal allows the use of a lower amount of optical power or energy than would otherwise be needed if an optical signal alone was used for the same purpose and effectiveness. The application of the electrical signal may precondition the nerve tissue such that a lower-power optical signal can be used to trigger the desired NAP, which otherwise would take a higher-power optical signal were the electric signal not applied. Some embodiments include an implanted nerve interface having a plurality of closely spaced electrodes placed transversely and/or longitudinally to the nerve and a plurality of optical emitters.

Abstract: An exemplary method includes performing a capture threshold assessment using a bipolar electrode configuration, deciding if capture occurred for a maximum energy value of the capture threshold assessment and, if capture did not occur, then performing a lead impedance test for the lead associated with the bipolar electrode configuration. Such a test may aim to detect an insulation defect and/or a conductor defect. Other exemplary methods, devices, systems, etc., are also disclosed.

Abstract: A medical device system includes electrodes for delivering cardiac pacing pulses to a patient's heart, a cardiac sensing module coupled to the electrodes and a cardiac pacing module coupled to the electrodes for generating cardiac pacing pulses. An acoustical sensor is used for obtaining heart sound signals. The system includes a processor that is configured to establish multiple conditions during which heart sound signals are received. The processor derives heart sound signal parameters from the heart sound signals and determines a heart sound profile comprising a trend of each of the heart sound signal parameters with respect to the multiple established conditions.

Abstract: In one aspect a system includes an external communication device configured to interrogate a pulse generator, an external programmer device communicatively coupled to the external communication device; the external programmer device configured to receive a listing of valid electrode pairs from the pulse generator through the external communication device, the external programmer device configured to prevent a pacing, sensing, or shocking vector from being programmed by the user if a pair of electrodes needed for the vector are not included within the listing of valid electrode pairs. In another aspect a system includes an implantable medical device configured to detect the presence or absence of electrodes on an implanted stimulation lead coupled to the implantable medical device and to generate a valid electrode pair listing and compare the programmed electrode pairs with the valid electrode pair listing. Other embodiments are also included herein.

Abstract: An implantable device includes a device body and at least one anchoring unit configured and arranged for anchoring the device body in a patient upon implantation. The anchoring unit includes a resorbable material that resorbs into the patient over a period of time after implantation.

Abstract: In general, the invention is directed to a medical device implantable in a body of a patient. The device includes a housing with a plurality of collapsible fixation structures coupled to the housing, and can be in a collapsed configuration or an expanded configuration. The device assumes a collapsed configuration when in the bore of an insertion device, and assumes the expanded configuration when expelled from the insertion device into the body of the patient. The extended fixation structures engage the tissues in the body and restrict migration. One exemplary application of the invention is in the context of a microstimulator, with a pulse generator housed in the housing and one or more electrodes coupled to the housing. The fixation structures help keep the electrodes proximate to the tissues that are to receive the stimulation.

Abstract: A quality control system in combination with an ECG data analysis system to analyze ECG data acquired by an ambulatory electrocardiography device via a cable having a plurality of leads connected to a subject is provided. The quality control system includes a memory having programmable instructions for execution by a processor to perform the steps of calculating a trend of a quality score in the ECG data dependent on a noise content in the ECG data; and calculating a probability that one of a hardware and the Hookup personal, each associated with collecting the ECG data from the subject, is a substantial cause of the quality score for the ECG data. The probability can be calculated based on a comparison the trend of the quality score associated with the Hookup personnel versus the trend of the quality score of the hardware employed in acquiring the ECG data.

Abstract: An active implantable medical device such as a cardiac prosthesis, including ventricular capture testing by analysis of an endocardial acceleration signal. The device isolates in an endocardial acceleration (“EA”) signal an EA component, extracts from it, n representative indicators (PEA_i, LEA_i), and forms a vector EA (X_i) from these indicators. A classifier allows acquiring reference EA signals at a stimulation energy level sufficient to cause a capture, and in spontaneous rhythm in the absence of ventricular pacing and forms a corresponding plurality of first reference EA vectors. The n-dimensional space of the EA vectors is partitioned into two corresponding subspaces. The presence or absence of a capture is discriminated based on the position of the current EA vector (X_i) in one or other of these two sub-spaces.

Abstract: An electrical lead including a conductor assembly, an electrode, and a thermally sensitive material. The conductor assembly has one or more conductors. The electrode is in electrical communication with one of the conductors and has an outer contact adapted for contacting adjacent body tissue of a patient. The thermally sensitive material is electrically connected between the one conductor and the electrode outer contact, and is configured to exhibit high impedance in the presence of currents considered unsafe to the patient, thereby preventing the unsafe currents from flowing through the thermally sensitive material and through the electrode outer contact potentially causing the adjacent body tissue to increase in temperature to an unsafe level. The unsafe currents cause the thermally sensitive material to increase in temperature, thereby causing the material to transition to a high impedance state.

Abstract: A parameter value is computed for a segment of a cardiac-related signal. In accordance with various example embodiments, a system includes a computer circuit configured to identify cardiac cycles within a segment of a cardiac-related signal, such as an ECG. At least one feature point is identified within the cardiac cycles. For each identified feature point, a signal-to-noise ratio (SNR) representative of the ratio of signal energy to noise energy is computed for a cardiac cycle subsegment containing the identified feature point. A validity characteristic of the feature point is determined based upon the signal-to-noise ratio, and a parameter value is computed by combining feature points contained within the segment, based upon the determined validity characteristics of the feature points.

Abstract: An implantable lead having a distal assembly including a coupler, a fixation helix secured to the coupler, a housing in which the fixation helix and the coupler are disposed, and a resilient seal that is fixedly secured to the coupler between proximal and distal ends thereof and able to translate with the coupler relative to the housing. The seal is positioned to sealingly engage an internal surface of the housing. When the coupler is translated such that the fixation helix is in a fully extended position, the seal is positioned to substantially seal off the housing to prevent tissue ingrowth.