Abstract: Systems and methods that use computer vision techniques in connection with robotic surgery are discussed. A robotic surgery system may include an implantable device engagement sub-system, a targeting sub-system, and/or an insertion verification sub-system. The system may use computer vision techniques to facilitate implanting a micro-manufactured bio-compatible electrode device in biological tissue (e.g., neurological tissue such as the brain) using robotic assemblies. The system can attach, via robotic manipulation, the electrode to an engagement element of an insertion needle.

Abstract: A portable, handheld device for fluorescence-based imaging is provided. The device comprises a wireless communication device having a sensor configured to detect optical signals. The device further comprises an assembly configured to receive and secure the wireless communication device therein. The assembly includes a housing, at least one light source coupled to the housing, a power supply, and an optical filter holder coupled to the housing and configured to receive one or more optical filters. An endoscope portion of the device is positioned relative to the sensor to visualize at least a portion of a confined anatomical space and to receive optical signals from a visualized, illuminated portion of a target positioned within the confined anatomical space. A processor of the device includes image analysis software and is configured to produce a composite representation of the illuminated portion of the target positioned within the confined anatomical space.

Abstract: Systems and methods are provided in which devices that are employed during a medical procedure are adaptively configured during the medical procedure, based on input or feedback that is associated with the current state, phase or context of the medical procedure. In some example embodiments, the input is obtained via the identification of one or more medical instruments present within a region of interest, and this input may be employed to determine configuration parameters for configuring the device. In other example embodiments, the input may be based on the image-based detection of a measure associated with the phase or context of the medical procedure, and this input may be employed to adaptively control the device based on the inferred context or phase of the medical procedure. In other embodiments, images from one imaging modality may be employed to adaptively switch to another imaging modality.

Abstract: Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.

Abstract: An adhesive patch for attaching at least one EM probe to a subject's body, the adhesive patch comprising a planar member having at least one layer of radiation absorbing material and having at least one opening formed within the radiation absorbing material to allow the propagation of EM radiation via the opening from one side of the planar member to the other. The adhesive patch further comprises at least one layer of an adhesive attached over at least part of a bottom surface of the planar member, which adhesive layer may be applied so as to form a pattern on the bottom surface, the pattern comprising at least one adhesive-covered portion and at least one adhesive-free portion.

Abstract: An ultrasound endoscope includes: an ultrasound transducer; a balloon groove in which a balloon band is fitted; a contact portion that constitutes a bottom surface of the balloon groove; a first wall portion that constitutes a proximal end side of the balloon groove and in which a first distance that is a distance from a center of a cross section orthogonal to an extension direction of the insertion portion to an outer circumference of the first wall portion is larger than a second distance that is a distance from the center of the cross section to the bottom surface; and a second wall portion that constitutes a distal end side of the balloon groove, in which a distance from the center of the cross section to an outer circumference of the second wall portion is larger than the second distance, and that includes a notch portion.

Abstract: A method of non-invasively monitoring the respiration of a patient comprises: transmitting ultrasound into the body toward an internal structure of the patient's body, the internal structure being one of the liver, the spleen or a kidney; selecting a depth range; measuring the phase of ultrasound echo signals from the internal structure at multiple points along the depth range for at least a first and a second echo signal, the first and second echo signals being received at different times; detecting the motion of the internal structure within the patient's abdomen by reference to differences in the measured phase between the first and the second echo signals; and thereby monitoring the respiration of the patient by associating movement of the internal structure with movement caused by respiration.

Abstract: A biological analysis device includes: a pulse pressure calculation unit that calculates a pulse pressure index related to a pulse pressure of a biological body; an average blood pressure calculation unit that calculates an average blood pressure index related to an average blood pressure of the biological body; and a blood pressure calculation unit that calculates a systolic blood pressure and a diastolic blood pressure in accordance with the pulse pressure index and the average blood pressure index. At least one of the pulse pressure index and the average blood pressure index is calculated in accordance with a blood flow index which is calculated from an intensity spectrum related to a frequency of light reflected and received from an inside of the biological body through radiation of a laser beam and is related to a blood flow of the biological body.

Abstract: Fresnel elevation focusing at a selected elevation angle is performed by transmitting a sequential set of Fresnel-focused ultrasound pulses, where a different Fresnel phase pattern is used for each pulse, and where the receive signals are coherently compounded. The different Fresnel patterns cause the secondary lobe energy to be reduced via averaging of variations of the pressure fields in the secondary lobe regions. In some embodiments, the method of coherently compounded Fresnel focusing is combined with coherently compounded defocused wave (e.g. plane wave or diverging wave) imaging in the azimuth direction. Each of the elevation slices are collected by changing the Fresnel patterns respectively employed when the sequence of plane waves or diverging waves are transmitted, such that the coherent compounding can benefit both planes simultaneously. Hadamard receive encoding and subsequent dynamic receive beamforming may be employed to further improve performance in the elevation direction.

Abstract: An integrated device of a patch and sensor assembly detects extravasation or infiltration. A transmitter is positioned to direct power into a body portion. A sensor is positioned to receive the power transmitted through the body portion. A substrate is attachable to an outer surface of the body portion and supports the transmitter and the sensor. A signal processor is coupled to the transmitter and the sensor for detecting a change in a fluid level in the body portion from extravasation or infiltration based on the power received by the sensor. A power supply is coupled to the transmitter and the sensor. An indicator is responsive to the signal processor to indicate a detected change in a fluid level in the body portion from extravasation or infiltration.

Abstract: Provided is a method of displaying location information of a bursa, which includes: obtaining shoulder ultrasound image data; detecting a fat layer located between a deltoid muscle and a tendon, based on information about an intensity of an echo signal contained in the shoulder ultrasound image data; detecting the bursa located between the fat layer and the tendon by using a location of the fat layer; and displaying the location information of the bursa on a shoulder ultrasound image generated based on the shoulder ultrasound image data.

Abstract: Devices, systems, and techniques for analyzing video information to objectively identify patient behavior are disclosed. A system may analyze obtained video information of patient motion during a period of time to track one or more anatomical regions through a plurality of frames of the video information and calculate one or more movement parameters of the one or more anatomical regions. The system may also compare the one or more movement parameters to respective criteria for each of a plurality of predetermined patient behaviors and identify the patient behaviors that occurred during the period of time. In some examples, a device may control therapy delivery according to the identified patient behaviors and/or sensed parameters previously calibrated based on the identified patient behaviors.

Abstract: An optical tracking system may comprise a reference marker unit stationarily disposed relative to a patient, a shape measurement unit configured to measure the three-dimensional shape of a specified part of the patient corresponding to a three-dimensional image, a tracking sensor unit configured to sense the reference marker unit and the shape measurement unit, and a processing unit. The processing unit may acquire a coordinate transformation relationship between the reference marker unit and the tracking sensor unit and a coordinate transformation relationship between the shape measurement unit and the tracking sensor unit based on a sensing result of the tracking sensor unit, acquire a coordinate transformation relationship between the specified part of the patient and the shape measurement unit based on a measurement result of the shape measurement unit, and define a coordinate system of the patient relative to the reference marker unit from the acquired coordinate transformation relationships.

Abstract: A miniature quantitative optical coherence elastography system with an integrated Fabry-Perot force sensor for in situ elasticity measurement of biological tissue is provided. The technique has great potential for biomechanics modeling and clinical diagnosis. The qOCE system contains a fiber-optic probe that exerts a compressive force to deform tissue at the tip of the probe. Using the space-division multiplexed optical coherence tomography signal detected by a spectral domain optical coherence tomography engine, probe deformation in proportion to the force applied is quantified, as well as the tissue deformation corresponding to the external stimulus. Simultaneous measurement of force and displacement allows for calculation of Young's modulus from the biological tissue.

Abstract: The present invention relates to a system and methods generally aimed at monitoring the angular orientation between two locations within a fluoroscopic image and especially for monitoring the angular orientation between two locations within a fluoroscopic image and a predetermined target angle.

Abstract: A Bowman's Refractive Index (BRI) for quantification of microdistortions in Bowman's Layer (BL) after Small Incision Lenticule Extraction (SMILE) is defined for a patient. BRI is summation of one or more areas of the OCT image of anterior edge of Bowman's layer, quantifies the smoothness of the Bowman's layer. The anterior edge of Bowman's layer is segmented into pixels. After segmentation, a 3rd order polynomial is curve fit to the segmented pixels of the edge of Bowman's layer. BRI is calculated by segmentation of the 3-Dimensional (3-D) OCT image. BRI acts as a marker for mechanical stability and is useful for diagnosis of disease and prognosis of treatments in human.

Abstract: Apparatus and methods are described for imaging a tool inside a portion of a subject's body that undergoes motion. A plurality of image frames are acquired of the portion of the subject's body. The image frames are image tracked by (a) automatically identifying at least a feature of the tool in at least a portion of the image frames, and (b) aligning the tool in image frames of the portion of the image frames, based on the automatic identifying. The image-tracked image frames of the portion of the subject's body are displayed as an image stream. Other embodiments are also described.

Abstract: A correspondence between frames of a set of medical image data is determined where the set of medical image data includes at least one frame acquired without contrast medium and at least one frame acquired with contrast medium. First data representing a first image frame acquired without contrast medium is received. Second data representing a second image frame acquired with contrast medium is received. A position of a feature of a medical device in the second image frame is determined at least partly on the basis of a position of the feature determined from the first image frame.

Abstract: A handheld, multipurpose medical diagnostic instrument capable of examining a patient's ears and eyes, detecting the patient's body temperature, capturing the patient's photograph for a patient profile and capturing the target of interest, and transmitting the collected data to an external device. The obtained images, video, and/or data may be displayed on at least one display screen for viewing in real time or for later viewing.

Abstract: An apparatus and method for sensing body information is provided. The apparatus includes: a light-emitting device configured to emit a light signal toward an object that is to be sensed; a light-receiving device configured to detect a reflected light signal reflected from the object; an image sensor configured to detect the reflected light signal reflected from the object; and a controller configured to selectively drive at least one of the light-receiving device and the image sensor according to a distance between the object and the light-emitting device and to sense volume information or blood flow information of the object by using the reflected light signal.