Patent number: 4994569
Abstract: Compounds of formula: ##STR1## in which R.sub.1 denotes 2-indolyl, 2-thienyl, 3-furyl, naphthyl, phenyl, or phenyl substituted with one or two halogen atoms, with alkoxy, alkyl, nitro, acylamino, alkylthio, acyl, trifluoromethoxy, morpholino, piperidino, amino, mono- or dialkylamino or, at the 3- and 4-positions, with methylenedioxyR.sub.2 denotes phenyl or phenyl substituted with one or two halogen atoms, with one or two alkyl radicals, with alkoxy, nitro, trifluoromethyl or hydroxy or, at the 3- and 4-positions, with methylenedioxy andeither X denotes oxygen andR.sub.3 denotes phenyl R.sub.4, R.sub.5 and R.sub.6 denote hydrogen, orR.sub.3 and R.sub.4 denote hydrogen, R.sub.5 denotes hydrogen or methyl and R.sub.6 denotes phenyl or one of R.sub.3 and R.sub.4 denotes methyl and the other hydrogen, R.sub.5 denotes hydrogen and R.sub.6 denotes phenyl,or X denotes sulphur, R.sub.3 denotes phenyl and R.sub.4, R.sub.5 and R.sub.
Type:
Grant
Filed:
November 1, 1989
Date of Patent:
February 19, 1991
Assignee:
Rhone-Poulenc Sante
Inventors:
Jean-Dominique Bourzat, Claude Cotrel, Claude Guyon, Philippe Pitchen