Patents Examined by Shahram Sharareh
  • Acetic acid as a contrast in reflectance confocal imaging of tissue
    Patent number: 6187289
    Abstract: A method for using acetic acid as a contrast agent during reflectance confocal imaging of normal and neoplastic tissue, particularly epithelium. In one aspect, the invention includes a method of using acetic acid as a contrast agent for confocal imaging of cells, including applying acetic acid to the diagnostic tissue sample in sufficient concentration to induce a small scale alteration of the index of refraction of nuclei in the cells; and imaging such cells using a reflectance confocal imaging system.
    Type: Grant
    Filed: October 20, 1998
    Date of Patent: February 13, 2001
    Assignee: Board of Regents, The University of Texas System
    Inventors: Rebecca Richards-Kortum, Rebekah Drezek, Colin Smithpeter, Andres F. Zuluaga
  • Nuclear scintigraphic assessment of mucosal function
    Patent number: 6099821
    Abstract: A method is provided for assessing the functional integrity of a mucosal membrane, comprising: (a) locally administering a dosage of a radionuclide to the surface of a mucosal membrane of a mammal; and (b) employing dynamic scintigraphy to measure the absorption of the radionuclide into the bloodstream of the mammal.
    Type: Grant
    Filed: January 5, 1999
    Date of Patent: August 8, 2000
    Assignees: University of Virginia, University of Virginia Patent Foundation
    Inventors: Tyvin A. Rich, Alexander V. Kirichenko