Patents Examined by Shailenora Kumar
  • Patent number: 6472562
    Abstract: The present invention relates to compounds of the formula I, in which A, L, Y, and k have the meanings indicated in the specification and claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa and/or factor VIIa and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of conditions in which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: October 29, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Otmar Klingler, Gerhard Zoller, Elisabeth Defossa, Fahad A. Al-Obeidi, Armin Walser, James Ostrem