Abstract: Cellulose materials and methods of making the cellulose materials are described herein. The method can include contacting a cotton fabric with an oxidizing system to obtain an oxidized cotton material and processing the oxidized cotton material to form the cellulose material. The oxidizing system can include an aqueous mixture of a N-oxyl compound and a hypochlorite compound. During oxidation, the p11 of the aqueous mixture can be maintained at from 8.5 to 11. Cellulose products can be formed from the cellulose materials. For example, the cellulose products can be used to form a packaging material, a biomedical device or implant, a drug delivery material, a fiber, a textile material, a template for electronic components, or a separation membrane. Methods of making the cellulose product include dissolving or suspending an active ingredient in a medium comprising the cellulose material.
Type:
Grant
Filed:
November 7, 2022
Date of Patent:
April 30, 2024
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Abstract: The present application discloses regioselectively substituted cellulose esters, films made from the regioselectively substituted cellulose esters and methods for making the same. The regioselectively substituted cellulose esters are synthesized using trifluoroacetic anhydride and cellulose with various acyl donors or acyl donor precursors.
Type:
Grant
Filed:
January 26, 2023
Date of Patent:
March 26, 2024
Assignee:
Eastman Chemical Company
Inventors:
Casey Lynn Elkins, Robert Jacks Sharpe, Bin Wang
Abstract: The disclosure provides redispersible CNC. The CNC disclosed herein is redispersible in non-polar and polar organic solvents as well as polar and non-polar polymers such as polyethylene or polypropylene. The disclosure surprisingly also provides redispersible CNC bearing improved redispersion in aqueous systems and most particularly in high ionic strength aqueous systems which usually require significant mixing energy to achieve dispersion.
Type:
Grant
Filed:
May 15, 2018
Date of Patent:
March 12, 2024
Assignee:
CELLUFORCE INC.
Inventors:
Philippe Bourassa, Myriam Methot, Richard Berry
Abstract: Provided is an oxidized cellulose, a 13C solid-state NMR spectrum of the oxidized cellulose including a number of peaks in a range of from 165 ppm to 185 ppm, which can be produced by oxidizing a cellulose raw material with a hypochlorous acid or salt thereof having an available chlorine concentration of from 6% by mass to 14% by mass, while adjusting the pH in a range of from 5.0 to 14.0.
Type:
Grant
Filed:
August 2, 2019
Date of Patent:
March 5, 2024
Assignee:
TOAGOSEI CO., LTD.
Inventors:
Daisuke Kamiya, Shiroshi Matsuki, Jun Takada
Abstract: There is provided a method for producing a depolymerized cellulose ether having yellowness reduced. More specifically, there is provided a method for producing a depolymerized cellulose ether comprising a depolymerization step of depolymerizing a cellulose ether with an aqueous solution of acid in the presence of a polyhydric alcohol having 2 to 6 carbon atoms.
Abstract: A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
Type:
Grant
Filed:
July 31, 2019
Date of Patent:
January 16, 2024
Assignee:
Covidien LP
Inventors:
Rachit Ohri, Phillip D. Blaskovich, Min-Shyan Sheu, Petra Brockfeld
Abstract: A silicon glycan is provided. The silicon glycan comprises a glycoside moiety, independently selected organosilicon moieties, and beta-amino alcohol moieties joining the organosilicon moieties to the glycoside moiety. The glycoside moiety comprises independently selected saccharide moieties, which may be substituted with hydrocarbyl groups, ether moieties, and/or amine moieties. A method of preparing the silicon glycan is also provided. The method includes reacting (A) an aminoethyl polysaccharide and (B) an epoxide-functional organosilicon compound, to give the silicon glycan. The method may include preparing the aminoethyl polysaccharide (A) by first reacting (At) a hydroxyl-functional polysaccharide and (A2) an aziridinium halide compound to give the aminoethyl polysaccharide (A).
Type:
Grant
Filed:
December 26, 2019
Date of Patent:
December 19, 2023
Assignees:
DOW SILICONES CORPORATION, DOW GLOBAL TECHNOLOGIES LLC
Inventors:
Marc-Andre Courtemanche, Michael Salvatore Ferritto, Emmett Partain, Wendy Xu
Abstract: The application discloses a method for preparing chitin highly dispersible in aqueous phase and prepared chitin. After chitin is ground, dissolved, modified with glycidol and purified, a final product glycidol chitin is obtained. The glycidol chitin prepared according to this method has good solubility in purified water, and the concentration can reach 100 mg/mL, which is obviously different from common insoluble or poorly soluble chitin derivatives. Glycidol chitin may have a wide range of application prospects in biomedicine, cosmetics, absorbable materials, and other related aspects.
Type:
Grant
Filed:
May 31, 2022
Date of Patent:
December 5, 2023
Assignee:
Hangzhou Singclean Medical Products Co., Ltd
Abstract: Provided is a novel manufacturing method whereby a carboxymethylated cellulose nanofiber dispersion having high tarnasparency can be obtained economically. In carboxymethylation of cellulose in the present invention, mercerization is performed in water as the main solvent, after which carboxymethylation is performed in a solvent mixture of water and an organic solvent, By defibrating the resultant carboxymethylated cellulose, a carboxymethylated cellulose nanofiber dispersion having high transparency can be obtained economically.
Type:
Grant
Filed:
December 5, 2018
Date of Patent:
August 22, 2023
Assignee:
NIPPON PAPER INDUSTRIES CO., LTD.
Inventors:
Kazuhiko Inoue, Takeshi Nakatani, Yusuke Tada
Abstract: 8-Hydroxy quinoline derivative compounds for enhancing telomerase reverse transcriptase (TERT) expression, and methods for using the same, are provided. These compounds and methods find use in a variety of applications in which increased expression of telomerase reverse transcriptase is desired.
Type:
Grant
Filed:
May 18, 2011
Date of Patent:
July 18, 2023
Assignee:
Sierra Sciences, Inc.
Inventors:
William H. Andrews, Lancer K. Brown, Laura A. Briggs, Federico C. A. Gaeta, Hamid Mohammadpour, Mieczyslaw A. Piatyszek
Abstract: Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).
Type:
Grant
Filed:
July 9, 2021
Date of Patent:
July 11, 2023
Assignees:
Fimbrion Therapeutics, Inc., GlaxoSmithKline Intellectual Property Development Limited
Inventors:
Michael Joseph Bishop, Eugene L. Stewart, Katherine Louisa Widdowson, James Walter Janetka, Laurel Kathryn McGrane
Abstract: The application describes compositions that include maltosyl-isomalto-oligosaccharides with a desirable mass average molecular weight distribution. In some cases, the compositions can contain at least 3% mannitol.
Abstract: Processes for converting lignocellulose to feedstock and downstream products are disclosed. The processes may include acid treatment of lignocellulose to produce a fermentation feedstock. In various instances, the processes include recovery or recycling of acid, such as recovery of hydrochloric acid from concentrated and/or dilute streams. Downstream products may include acrylic acid-based products such as diapers, paper and paper-based products, ethanol, biofuels such as biodiesel and fuel additives, and detergents.
Abstract: The present disclosure is related to dietary supplements. For example, this disclosure relates to compositions that include, for example, one or more agents that decrease the concentration of cyclooxygenase-2, decrease the concentration of transient receptor potential cation channel subfamily V member 1, and/or decrease calcitonin gene-related peptide concentration. In some embodiments, a composition as provided herein includes apigenin present in an amount of about 1% to about 5% w/w of the composition; and hesperidin present in an amount of about 90% to about 99% w/w of the composition. Such compositions are useful for decreasing joint pain and/or inflammation.
Type:
Grant
Filed:
September 3, 2020
Date of Patent:
May 9, 2023
Assignee:
BioRelief, LLC
Inventors:
Gary Jeffery Ramey, V. A. Shiva Ayyadurai, Prabhakar Deonikar
Abstract: Provided herein are compounds having the structure of Formulas A-D and compositions thereof for use in the detection and quantification of viral neuraminidase. In particular, the compounds may be useful for the evaluation of viral strains and for vaccine evaluation.
Abstract: The present disclosure relates to a composition comprising (20S,24R)-6-O-?-D-glucopyranosyl(1?2)-?-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an active ingredient. In addition, it relates to a method for preventing or improving menopausal symptoms, which comprises administering an effective amount of (20S,24R)-6-O-?-D-glucopyranosyl(1?2)-?-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to a subject in need thereof. The novel ginsenoside has a superior effect of preventing or improving menopausal symptoms with a low risk of breast cancer.
Abstract: A number of triterpene saponin variants with different modifications on their central glycosyl ester linkage are described. Also described are methods of making and method of using such triterpene saponin variants.
Type:
Grant
Filed:
December 19, 2016
Date of Patent:
April 18, 2023
Assignee:
Memorial Sloan-Kettering Cancer Center
Inventors:
Derek S. Tan, David Y. Gin, William E. Walkowicz, Alberto Fernandez-Tejada, Govindaswami Ragupathi
Abstract: Provided herein is chitosan dually derivatized with arginine and gluconic acid; and methods of making and using the same, e.g., for gene delivery in vivo.