Patents Examined by Shaojia Anna Jiang
  • Patent number: 10076131
    Abstract: The present invention generally relates to the field of nutrition. In particular the present invention relates to infant nutrition in the post natal period and in early life, more particular during the age period of 6-36 months or during a part thereof. One embodiment of the present invention is a kit of diet compositions for children during the age period of 6-36 months or during a part thereof, wherein the macronutrient content of the compositions is gradually changing in the form of a straight line from a composition that comprises about 40-50% energy from fat and about 40-49% energy from carbohydrates for children at the age of 6 months to a composition that comprises about 30-35% energy from fat and about 50-55% energy from carbohydrates for children at the age of 36 months, and its use to prevent obesity later in life.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: September 18, 2018
    Assignee: Nestec S.A.
    Inventors: Yasaman Shahkhalili, Kevin Acheson, Katherine Mace, Julie Moulin, Irene Zbinden, Olivier Aprikian, Theresa Voss
  • Patent number: 10066028
    Abstract: The method of fabricating biocompatible cellulose nanofibrils produces cellulose nanofibrils from used agro-waste Borassus flabellifer leaf stalks. The method uses a three-step process, including alkali treatment, bleaching, and acid hydrolysis to produce cellulose nanofibrils, which may be converted to pellets for storage. The pellets may be converted to a transparent film for cell attachment by dispersion in water and heating in a hot air oven. Testing shows that cellulose nanofibrils made by the method easily attract human mesenchymal stem cells and will be applicable for skin tissue engineering applications.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: September 4, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Jegan Athinarayanan, Ali A. Alshatwi, Vaiyapuri Subbarayan Periasamy
  • Patent number: 10052373
    Abstract: The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic carbohydrate is a Streptococcus pneumoniae type 3 capsular polysaccharide related carbohydrate and the carrier molecule is a glycosphingolipid. Said conjugate and pharmaceutical composition thereof are useful for immunization against diseases associated with Streptococcus pneumoniae, and more specifically against diseases associated with Streptococcus pneumoniae type 3.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: August 21, 2018
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Dominea Rathwell, Sharavathi Guddehalli Parameswarappa, Subramanian Govindan, Chakkumkal Anish, Claney Lebev Pereira, Peter H. Seeberger, Felix Bröcker
  • Patent number: 10053483
    Abstract: Provided in the present invention are novel key intermediates of selamectin and the preparation method thereof. Also provided is a new synthesis process, using doramectin as a starting material, and obtaining selamectin via hydrogenation, oxidation, oximation and desugaring. The new process of the present invention has few steps, and is simple to operate, high in yield, low in cost and causes little pollution, and is more suitable for large scale industrial production.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: August 21, 2018
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Mingxing Yin, Jianchao Wu, Jian Chai
  • Patent number: 10047168
    Abstract: There is provided a process for the preparation of purified ?-(1,3)-D-glucans, comprising the steps of providing an aqueous ?-(1,3)-D-glucan initial solution having a pH of above 11.0, filtering the aqueous ?-(1,3)-D-glucan initial solution to obtain a ?-(1,3)-D-glucan containing filtrate, adjusting the pH of the ?-(1,3)-D-glucan containing filtrate with an acid to a pH of below 5.0 to obtain an acidic ?-(1,3)-D-glucan solution, and heating the acidic ?-(1,3)-D-glucan solution to a temperature in the range of 60 to 160° C.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: August 14, 2018
    Assignee: Cargill. Incorporated
    Inventors: Jacques André Christian Mazoyer, Jean-Pierre Lhonneur
  • Patent number: 10047169
    Abstract: There is provided a process for the preparation of purified ?-(1,3)-D-glucans, comprising the steps of providing an aqueous ?-(1,3)-D-glucan initial solution having a pH of above 11.0, filtering the aqueous ?-(1,3)-D-glucan initial solution to obtain a ?-(1,3)-D-glucan containing filtrate, adjusting the pH of the ?-(1,3)-D-glucan containing filtrate with an acid to a pH of below 5.0 to obtain an acidic ?-(1,3)-D-glucan solution, and heating the acidic ?-(1,3)-D-glucan solution to a temperature in the range of 60 to 160°C.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: August 14, 2018
    Assignee: Cargill, Incorporated
    Inventors: Jacques André Christian Mazoyer, Jean-Pierre Lhonneur
  • Patent number: 10047170
    Abstract: There is provided a process for the preparation of purified ?-(1,3)-D-glucans, comprising the steps of providing an aqueous ?-(1,3)-D-glucan initial solution having a pH of above 11.0, filtering the aqueous ?-(1,3)-D-glucan initial solution to obtain a ?-(1,3)-D-glucan containing filtrate, adjusting the pH of the ?-(1,3)-D-glucan containing filtrate with an acid to a pH of below 5.0 to obtain an acidic ?-(1,3)-D-glucan solution, and heating the acidic ?-(1,3)-D-glucan solution to a temperature in the range of 60 to 160° C.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: August 14, 2018
    Assignee: Cargill, Incorporated
    Inventors: Jacques André Christian Mazoyer, Jean-Pierre Lhonneur
  • Patent number: 10035863
    Abstract: There is provided a process for the preparation of purified ?-(1,3)-D-glucans, comprising the steps of providing an aqueous ?-(1,3)-D-glucan initial solution having a to pH of above 11.0, filtering the aqueous ?-(1,3)-D-glucan initial solution to obtain a ?-(1,3)-D-glucan containing filtrate, adjusting the pH of the ?-(1,3)-D-glucan containing filtrate with an acid to a pH of below 5.0 to obtain an acidic ?-(1,3)-D-glucan solution, and heating the acidic ?-(1,3)-D-glucan solution to a temperature in the range of 60 to 160° C.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: July 31, 2018
    Assignee: Cargill, Incorporated
    Inventors: Jacques André Christian Mazoyer, Jean-Pierre Lhonneur
  • Patent number: 10030078
    Abstract: Processes for making reduced molecular weight ethersuccinylated polysaccharides, for example ethersuccinylated starches are provided.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: July 24, 2018
    Assignee: The Procter & Gamble Company
    Inventor: Stephen Wayne Heinzman
  • Patent number: 10022449
    Abstract: The present invention relates to iota- and/or kappa-carrageenan in combination with a neuraminidase inhibitor for use as a medicament in the prophylactic or therapeutic treatment of a symptom, condition or disease caused by or associated with an infection by an influenza virus.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: July 17, 2018
    Assignee: MARINOMED BIOTECHNOLOGIE GmbH
    Inventors: Andreas Grassauer, Eva Prieschl-Grassauer, Christiane Meier, Marielle Konig-Schuster
  • Patent number: 10022454
    Abstract: Disclosed herein are compositions and methods for generating ribo-nucleic neutral (RNN) or deoxyribo-nucleic-neutral (DNN) polynucleotides with reduced anionic charge, for improved intracellular delivery. Also disclosed herein are methods of using RNN and DNN compositions.
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: July 17, 2018
    Assignee: LipoSciences, LLC
    Inventor: Scott G. Petersen
  • Patent number: 10011628
    Abstract: Disclosed is tri- or tetravalent sialic acid derivatives comprising a core moiety to which 3 or 4 sialic acid residues are connected via a linker. Such derivatives inhibit the binding of adenovirus to human cells, whereby infections, such as epidemic keratoconjunctivitis, may be treated or prevented by administration of the tri- or tetravalent sialic acid derivatives.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: July 3, 2018
    Assignee: ADENOVIR PHARMA AB
    Inventors: Niklas Arnberg, Rémi Caraballo, Mikael Elofsson
  • Patent number: 10005849
    Abstract: A process for producing a cellulose derivative, comprising: a first step including reacting a cellulose and a first reactant comprising a long-chain reactant for reacting with a hydroxy group of the cellulose to introduce a long-chain organic group having 5 or more carbon atoms, in a solid-liquid heterogeneous system, to form a cellulose derivative in a swollen state, the cellulose derivative having the long-chain organic group having 5 or more carbon atoms introduced therein and having a part of hydroxy groups of the cellulose remained, and performing solid-liquid separation to obtain the cellulose derivative as an intermediate; and a second step including reacting the intermediate cellulose derivative and a second reactant comprising a short-chain reactant for reacting with a remaining hydroxy group of the intermediate cellulose derivative to introduce a short-chain organic group having 4 or less carbon atoms to form a final cellulose derivative having the short-chain organic group having 4 or less carbon a
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: June 26, 2018
    Assignee: NEC Corporation
    Inventors: Kiyohiko Toyama, Masatoshi Iji, Shukichi Tanaka
  • Patent number: 10001488
    Abstract: Isotopically-labelled glycans and their synthesis and use as internal standards in the analysis by mass spectrometry of glycan mixtures is described. The methods of synthesis described herein may be used conveniently to prepare libraries of heavy glycans for use in the qualitative and quantitative identification of glycans in natural samples.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: June 19, 2018
    Assignee: Asocación Centro de Investigación Cooperativa en Biomaterials
    Inventors: Niels-Christian Reichardt, Begoña-Maria Echeverría Beistegui, Juan Etxebarria, Javier Calvo, Nerea Ruiz
  • Patent number: 9987376
    Abstract: A delivery system for use in the oral cavity, the system comprising a carrier for a bioactive substance. The carrier has a surface comprising oxygen-binding sites (X), and at least one link comprising a pentose group and one or more additional sugar groups, the pentose group being bonded to one of said oxygen binding sites (X) and wherein one or more bioactive molecules (R) are bonded directly to one of the sugar groups of the at least one link or to one or more substituents on one or more sugar groups in the at least one link.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: June 5, 2018
    Assignee: NORINVENT AB
    Inventor: Jonatan Moses
  • Patent number: 9980928
    Abstract: Hydroxy aliphatic substituted phenyl aminoalkyl ether compounds of formula (I), and compositions thereof, are useful as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or mental disorders associated with cognitive deficits.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: May 29, 2018
    Inventors: Josep R. Prous, Neus Serradell, Ramon Flores, Noemi Garcia-Delgado, Marcel-li Carbo Banus
  • Patent number: 9974802
    Abstract: Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases. In particular, compositions comprising a selectively depolymerized, branched galactoarabino-rhamnogalacturonate whose backbone is predominantly comprised of 1,4-linked galacturonic acid (GalA) moieties, with a lesser backbone composition of alternating 1,4-linked GalA and 1,2-linked rhamnose (Rha), which in-turn is linked to any number of side chains, including predominantly 1,4-b-D-galactose (Gal) and 1,5-?-L-arabinose (Ara) residues.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: May 22, 2018
    Assignee: Galectin Therapeutics, Inc.
    Inventors: Eliezer Zomer, Peter G. Traber, Anatole A. Klyosov, Elena Chekhova
  • Patent number: 9969763
    Abstract: The present invention relates to carbohydrate-di and tri lipidated cysteine based 1,2,3-triazoles useful as vaccine adjuvants of formula 1 The present invention also provides process for preparation of carbohydrate-di and tri lipidated cysteine based 1,2,3-triazoles. The carbohydrate-di and tri lipidated cysteine based 1,2,3-triazoles as vaccine adjuvants are useful in formulations for therapeutic and prophylactic vaccines against bacterial, viral, protozoan infections and cancer.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: May 15, 2018
    Assignee: Council of Scientific and Industrial Research
    Inventors: Halmuthur Mahabalarao Sampathkumar, Naresh Nalla, Sathyaseelan Sathyabama, Sabbana Surya Vamshi, Bonam Srinivasa Reddy, Veerjala Naveen Kumar
  • Patent number: 9949946
    Abstract: Inclusion complexes of pinocembrin with cyclodextrin or its derivatives and their preparation are provided. The inclusion complexes can be used to make drugs.
    Type: Grant
    Filed: November 11, 2008
    Date of Patent: April 24, 2018
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Song Wu, Guanhua Du, Yan Qi, Mei Gao, Qingyun Yang, Hongmei Guang, Wei Li, Yuehua Wang, Yuanfeng Tong
  • Patent number: 9951147
    Abstract: There is provided a process for the preparation of purified ?-(1,3)-D-glucans, comprising the steps of providing an aqueous ?-(1,3)-D-glucan initial solution having a pH of above 11.0, filtering the aqueous ?-(1,3)-D-glucan initial solution to obtain a ?-(1,3)-D-glucan containing filtrate, adjusting the pH of the ?-(1,3)-D-glucan containing filtrate with an acid to a pH of below 5.0 to obtain an acidic ?-(1,3)-D-glucan solution, and heating the acidic ?-(1,3)-D-glucan solution to a temperature in the range of 60 to 160° C.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: April 24, 2018
    Assignee: Cargill, Incorporated
    Inventors: Jacques Mazoyer, Jean-Pierre Lhonneur