Patents Examined by Shar Hashemi
  • Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone
    Patent number: 6716961
    Abstract: Chiral peptide nucleic acids are provided which hybridise strongly with complementary nucleic acids and have potential as antigene and antisense agents and as tools in molecular biology. The compounds have the formulae. where n is 1 to 200, B is a protected or unprotected base, X may be OH, Y may be H, and R′ and R″, which are the same or different, are H, C1-C6 alkyl, aryl or aralkyl or R′ or R″, together the carbon atoms to which they are attached, form a cycloalkyl ring and protected derivatives thereof.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: April 6, 2004
    Assignee: ISIS Innovation Limited
    Inventor: Gordon Lowe
  • Polymerase chain reaction system
    Patent number: 6699713
    Abstract: A portable polymerase chain reaction DNA amplification and detection system includes one or more chamber modules. Each module supports a duplex assay of a biological sample. Each module has two parallel interrogation ports with a linear optical system. The system is capable of being handheld.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: March 2, 2004
    Assignee: The Regents of the University of California
    Inventors: William J. Benett, James B. Richards, Paul L. Stratton, Dean R. Hadley, Fred P. Milanovich, Phil Belgrader, Peter L. Meyer
  • Method for measuring nucleotides
    Patent number: 6642004
    Abstract: The present invention discloses a one-pot, high-throughput method for the measurement of the amount of a nucleotide generated in a cell. The method is particularly effective in measuring changes in cyclic adenosine 3′,5′-monophosphate (cAMP) coupled to cell receptors in insects.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: November 4, 2003
    Assignee: FMC Corporation
    Inventors: Ratna Dargar, Muniratham K. Chaguturu
  • Primers for identifying aflatoxinogenic aspergilli and an improved method thereof
    Patent number: 6623932
    Abstract: The present invention relates to three sets of novel primers of SEQ ID Nos. 1-6, wherein said three sets of primer are designed from three genes omt, ord, and afl R respectively of aflatoxin biosynthesis pathway of fungi Aspergillus flavus and an improved method of identifying aflatoxinogenic aspergilli using said three sets of primers.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: September 23, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Haravey Krishnan Manonmani, Arun Chandrashekar, Eddiya Rati Rao
  • Methods and compositions for analyzing nucleic acids
    Patent number: 6620586
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the invention provides for methods and combinations for analyzing nucleic acids in a plurality of samples using a plurality of detectably different signature labels and a probe that is hybridizable to each of the target nucleic acids. The invention also provides for a method for quantifying a nucleic acid by analyzing the amount of a label, e.g., a photoactivatable label, attached to the target nucleic acid.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: September 16, 2003
    Assignee: Applied Gene Technologies, Inc.
    Inventor: Nanibhushan Dattagupta
  • Detection of group a Streptococcus
    Patent number: 6593093
    Abstract: The invention provides methods to detect Group A Streptococcus (GAS) in biological samples using real-time PCR. Primers and probes for the detection of GAS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GAS are further provided by the invention.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: July 15, 2003
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: James R. Uhl, Franklin R. Cockerill