Abstract: A dosage form is disclosed, which dosage form comprises an outside wall and an inside wall, which inside wall comprises means for changing its structural integrity in response to fluid having a pH greater than 5 that enters the dosage form, thereby changing the pH environment inside the dosage form and concomitantly causing the inside wall to change its structural integrity, thus causing the outside wall to collapse and be easily eliminated from a host.
Type:
Grant
Filed:
August 11, 1986
Date of Patent:
May 10, 1988
Assignee:
ALZA Corporation
Inventors:
Marc L. Bartoo, Patrick S. L. Wong, Felix Theeuwes, Brian Barclay