Patents Examined by Shean Wu
  • Patent number: 6695979
    Abstract: The instant invention relates to liquid crystal media comprising a dielectrically positive component (A), comprising compounds with high values of &Dgr;n of formula I and simultaneously a second dielectrically positive component (B), comprising one or more compounds of formula II wherein the parameters are as defined in the text and to liquid crystal displays comprising these media, in particular to TN-AMD displays.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: February 24, 2004
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Hideo Ichinose, Yukiomi Tanaka, Shinji Nakajima
  • Patent number: 5989451
    Abstract: This invention provides chiral thioindigo compounds for doping smectic liquid crystal hosts, wherein the compounds modulate a chiral bulk property of an induced chiral smectic liquid crystal phase upon irradiation at a wavelength in the visible range. Modulation of the chiral bulk property is effected by reversible trans-cis photoisomerization of the compound upon irradiation. The compounds maintain their rod-like shape in both isomeric forms, and hence do not destabilize the chiral smectic liquid crystal phase. Compounds according to the invention are useful in optical devices such as optical switches, displays, and memory.
    Type: Grant
    Filed: February 6, 1998
    Date of Patent: November 23, 1999
    Assignee: Queen's University at Kingston
    Inventors: Robert P. Lemieux, Liviu Dinescu
  • Patent number: 5846451
    Abstract: A crosslinking type liquid crystal polymer, an oriented crosslinking film thereof, and a method of producing the oriented crosslinking film are disclosed. The crosslinking type liquid crystal polymer comprises a liquid crystal polymer containing a polyfunctional azide compound represented by the following formula (A);R.sup.1 --(N.sub.3).sub.n (A)wherein R.sup.1 represents an organic group and n represents an integer of from 1 to 5.
    Type: Grant
    Filed: November 26, 1996
    Date of Patent: December 8, 1998
    Assignee: Nitto Denko Corporation
    Inventors: Shusaku Nakano, Amane Mochizuki, Hironori Motomura, Kyoko Izumi
  • Patent number: 5695691
    Abstract: The present invention concerns finely divided particles of compounds that provide flame retardancy and/or smoke suppressant properties to fibers, textiles, polymeric articles, paper, paint, coating and insulation. More particularly, the present invention concerns colloidal-sized particles of hydrated salts, organic phosphates, metal borates, polyamides, solid halogenated flame retardants with a melting point greater than 250.degree. C., molybdenum compounds, metallocenes, antimony compounds, zinc compounds, bismuth compounds and other solid chemicals which act as flame retardants or smoke suppressants. The present invention also concerns various milling processes to reduce these materials to colloidal sizes and to disperse them in water, organic liquids and meltable solids.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 9, 1997
    Assignee: Anzon, Inc.
    Inventors: John McLaughlin, Philip S. Podwirny, John C. Morley
  • Patent number: 5695681
    Abstract: Liquid-crystalline allenes of the formula I ##STR1## where M is a mesogenic group,R.sup.1 and R.sup.2 are hydrogen or a C-organic radical having 1-8 carbon atoms,R.sup.3 is a C-organic radical having 1-30 carbon atoms,X.sup.1 is --(CH.sub.2).sub.q --O--(CH.sub.2).sub.p --,--(CH.sub.2).sub.q --NR.sup.4 --(CH.sub.2).sub.p --,--(CH.sub.2).sub.q --CO--O--(CH.sub.2).sub.p --,--(CH.sub.2).sub.q --O--CO--(CH.sub.2).sub.p --,--(CH.sub.2).sub.q --CO--NR.sup.4 --(CH.sub.2).sub.p -- or--(CH.sub.2).sub.q --NR.sup.4 --CO--(CH.sub.2).sub.p --,R.sup.4 is hydrogen or an alkyl radical having 1-4 carbon atoms,p is from 1 to 20, andq is from 0 to 20,where the definitions of R.sup.2 and R.sup.3 can also be interchanged, are used in optical display elements.
    Type: Grant
    Filed: March 27, 1996
    Date of Patent: December 9, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Karl Siemensmeyer, Carsten Tschierske, Kerstin Zab
  • Patent number: 5663375
    Abstract: Pharmaceutical compounds of the formula ##STR1## in which n is 0, 1 or 2 and R.sup.1 is attached at any of the positions 7, 8, 9 or 10, and each R.sup.1 is halo, carboxy, trifluoromethyl, hydroxy, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkylthio, hydroxy-C.sub.1-4 alkyl, hydroxy-C.sub.1-4 alkoxy, nitrogen-containing heterocyclyl, nitro, trifluoromethoxy, --COOR.sup.5 where R.sup.5 is an ester group, --COR.sup.6, --CONR.sup.6 R.sup.7 or --NR.sup.6 R.sup.7 where R.sup.6 and R.sup.7 are each hydrogen or C.sub.1-4 alkyl;R.sup.2 is phenyl, naphthyl or heteroaryl selected from thienyl, pyridyl, benzothienyl, quinolinyl, benzofuranyl or benzimidazolyl, said phenyl, naphthyl and heteroaryl groups being optionally substituted, or R.sup.2 is furanyl optionally substituted with C.sub.1-4 alkyl;R.sup.3 is nitrile, carboxy, --COOR.sup.8 where R.sup.8 is an ester group, or --CONR.sup.9 R.sup.10 where R.sup.9 and R.sup.10 are each hydrogen or C.sub.1-4 alkyl; andR.sup.4 is --NR.sup.11 R.sup.12, --NR.sup.11 COR.sup.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: September 2, 1997
    Assignees: Eli Lilly and Company, Lilly Industries Limited
    Inventors: Michael Brunavs, Colin Peter Dell, Peter Thaddeus Gallagher, William Martin Owton, Colin William Smith
  • Patent number: 5589102
    Abstract: Benzene derivatives of the formula I ##STR1## in which R, A.sup.1, A.sup.2 X, L.sup.1, L.sup.2 m and n are as defined in claim are suitable as components of liquid-crystalline media.
    Type: Grant
    Filed: September 5, 1995
    Date of Patent: December 31, 1996
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Ekkehard Bartmann, Kazuaki Tarumi
  • Patent number: 5549883
    Abstract: A chemically defined polymeric carrier comprising a series of .alpha.-amino acids in any combination containing side chains to which diagnostic/therapeutic and chelating agents can be covalently joined through cleavable linkers either directly or covalently joined through cleavable linkers after chemical modification of the side chains. Hydrazone, disulfide, and ester linkages in any combination can be present in the polymeric carrier between the side chains of the .alpha.-amino acids and the agents. The presence of a particular covalent linkage between the side chain and the agent in the carrier is determined by the functional group present in the side chain of the .alpha.-amino acid and the functional group present in the agent. The .alpha.-amino acids with side chains to which agents do not covalently join can function as spacers to minimize interaction between bulky molecules attached to the polymeric carrier. In addition, those .alpha.
    Type: Grant
    Filed: June 3, 1993
    Date of Patent: August 27, 1996
    Assignee: NeoRx Corporation
    Inventors: Ananthachari Srinivasan, Vivekananda M. Vrudhula, Diana I. Brixner
  • Patent number: 5527885
    Abstract: This invention relates to chelating agents useful for coupling metal ions to biologically active molecules. In particular, isothiocyanate derived thiocarbonyls for chelating metals such as technetium are provided that can be conjugated to a targeting molecule such as an antibody, a peptide or a protein.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: June 18, 1996
    Assignee: Cytogen Corporation
    Inventors: Daniel J. Coughlin, Benjamin A. Belinka, Jr.
  • Patent number: 5514296
    Abstract: A glassy thermotropic chiral nematic liquid crystalline composition comprises a glassy chiral nematic compound of low molar mass that includes a cycloaliphatic radical, a nematogenic moiety, and a chiral moiety, or a mixture of a nematic liquid crystalline compound of low molar mass that includes a cycloaliphatic radical and a nematogenic moiety and a chiral compound of low molar mass that includes a chiral moiety. Each cycloaliphatic radical contains 4 to about 18 carbon atoms. An optical device is formed from the described glassy thermotropic chiral nematic liquid crystalline composition.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: May 7, 1996
    Assignee: The University of Rochester
    Inventors: Shaw H. Chen, Hongqin Shi
  • Patent number: 5498365
    Abstract: An electrooptical systemwhich between 2 electrode layers contains a PDLC film comprising a liquid crystal mixture forming microdroplets in an optically isotropic, transparent polymer matrix,in which one of the refractive indices of the liquid crystal mixture is matched to the refractive index of the polymer matrix, andwhich in one of the two switching states has reduced transmission compared with the other state independent of the polarization of the incident light,characterized in that the precursor of the PDLC film comprisesa) 50-90 wt. % of a liquid crystal mixture containing one or more compounds of the formula I ##STR1## b) 15-49.5 wt. % of the precursor of the polymer matrix.
    Type: Grant
    Filed: August 13, 1993
    Date of Patent: March 12, 1996
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Patrick Nolan, David Coates
  • Patent number: 5498368
    Abstract: A liquid crystal device wherein the liquid crystal material is a siloxane-containing compound characterised by the the general formula ##STR1## wherein R is a C.sub.1-10 alkyl or ##STR2## each R' is a C.sub.1-4 alkyl, T is ##STR3## X is an alkyl or halogen-substituted alkyl group having at least one chiral center, Y is F, m is 0, 1 or 2 and n is 10, 11 or 12. Also claimed is a device wherein the liquid crystal material is disposed between a pair of substrates.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: March 12, 1996
    Assignee: Dow Corning Limited
    Inventor: Harry J. Coles
  • Patent number: 5496929
    Abstract: The invention concerns a radiopharmaceutical product having in particular a cerebral tropism comprising a nitruro complex of a transition metal and the method for preparing said product. This complex satisfies the formula (M.tbd.N)L.sup.1 L.sup.2 (I) in which M is a transition metal, such as Tc99m, Re 186 or Re188, and L.sup.1 and L.sup.2, which may be identical or different, satisfy the formula ##STR1## in which R.sup.1 and R.sup.2 may be alkyl radicals, V and W may be O, S or Se, n=0 or 1, l=0 or 1, m=0 or 1, and X represents N--C, C, or As.
    Type: Grant
    Filed: May 19, 1994
    Date of Patent: March 5, 1996
    Assignee: Cis Bio International
    Inventors: Roberto Pasqualini, Emmanuel Bellande, Ve/ ronique Comazzi, Jacques Laine/
  • Patent number: 5496533
    Abstract: Rhenium complexes of formula (I), radiolabelled complexes thereof or pharmaceutically acceptable salts thereof: ##STR1## wherein R is straight or branched chain C.sub.1-10 alkyl, C.sub.1-10 alkenyl, C.sub.1-10 alkynyl optionally substituted by cycloalkyl or aryl; C.sub.1-10 cycloalkyl optionally substituted by straight or branched chain alkyl, alkenyl, alkynyl or aryl; or aryl optionally substituted by straight or branched chain alkyl, alkenyl, alkynyl or cycloalkyl for use in liver cancer therapy and metastasis of cancer.
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: March 5, 1996
    Assignee: Australian Nuclear Science & Technology Organisation
    Inventors: Timothy W. Jackson, Masaharu Kojima, Richard M. Lambrecht
  • Patent number: 5493026
    Abstract: Disclosed are certain cocaine analogs useful for imaging of cocaine receptors and dopamine receptors. Also disclosed are analogs useful for imaging diagnostics for Parkinson's disease.
    Type: Grant
    Filed: October 25, 1993
    Date of Patent: February 20, 1996
    Assignees: Organix, Inc., The General Hospital Corporation, President and Fellows of Harvard College, Northeastern University
    Inventors: David R. Elmaleh, Bertha K. Madras, Robert N. Hanson, Peter Meltzer
  • Patent number: 5489425
    Abstract: A group of functionalized polyamine chelants that form complexes with rhodium are disclosed. The rhodium complexes can be attached to an antibody or antibody fragment and used for therapeutic or diagnostic purposes.
    Type: Grant
    Filed: March 15, 1993
    Date of Patent: February 6, 1996
    Assignee: The Dow Chemical Company
    Inventors: William J. Kruper, Jr., Douglas K. Pollock, William A. Fordyce, Machael J. Fazio, Muthiah N. Inbasekaran, Ramaiah Muthyala
  • Patent number: 5486311
    Abstract: An optically erasable read-and-write liquid crystal/side-chain liquid crystalline polymer composition, and method of making recordation on the same, are disclosed. The liquid crystal/side-chain liquid crystalline polymer composition of the present invention comprises: (1) from 45% to 85% of a nematic type ester-based liquid crystal and (2) from 15% to 55% of side-chain polymethylsiloxane liquid crystalline polymer having a molecular weight between about 4,000 to 10,000. The side-chain polymethylsiloxane polymer is prepared by graft-polymerization of a biphenyl derivative having a terminal saturated or unsaturated alkyl group, which can be either symmetrical or asymmetrical, with a polymethylsiloxane to form the liquid crystal side-chain polymethylsiloxane polymer of the present invention. Data are recordable on the recording medium of the present invention using a laser beam heating, and are erasable by applying an external electrical field.
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: January 23, 1996
    Assignee: National Science Council
    Inventors: Ging-Ho Hsiue, Jow-Tsong Shy, Jang-Jeng Liang, Wen-Chang Chiang
  • Patent number: 5484551
    Abstract: Compounds containing a 4-[(E)-alk-2-enoyloxy]benzoate group and liquid crystalline mixtures which contain such compounds and the use of such compounds and, respectively, mixtures in electro-optical indicating devices.The compounds are of the formula ##STR1## wherein R.sup.1 is alkyl with 1 to 12 carbon atoms;X.sup.1, X.sup.3 each independently are halogen or hydrogen; andX.sup.2 is halogen or cyano.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: January 16, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Stephen Kelly, Martin Schadt
  • Patent number: 5484552
    Abstract: A liquid crystal display is made from an encapsulated liquid crystal structure comprising a liquid crystal composition dispersed in a containment medium. Selected additives may be added to the encapsulated liquid crystal structure to improve performance characteristics such as the operating field, the hysteresis, and the voltage holding ratio.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: January 16, 1996
    Assignee: Raychem Corporation
    Inventors: Mark F. Wartenberg, Harriette Atkins, Robert H. Reamey, Laurence Welsh, James Strain, Janusz Wojtowicz, Wayne Montoya, Paul S. Drzaic, John Havens, Akira Tomita, Aldrich N. K. Lau
  • Patent number: RE35462
    Abstract: The present invention relates to compounds of the formula ##STR1## in which Z is a halogen atom, a cyano group or a hydroxyl group,n is 0, 1 or 2,R' is a radical of the formulaR"'--[Si(R*).sub.2 ].sub.x (CH.sub.2).sub.y R""-- (9),in whichx is the number 0 or 1,y is an integer from 1 to 18,R"'is a defined in the description,R* is identical or different, optionally substituted C.sub.1 - to C.sub.18 -hydrocarbon or hydrocarbonoxy radicals,R"" is a phenylene or biphenylene radical or a radical of the formula --E--, whereE is a divalent radical of the formula --O-- or --[Si(R*).sub.2 ].sub.z --, andz is the number 0 or 1,and the compounds contain at least one group of the formula --Si(R*).sub.2 -- per molecule, and the radicalR" is a cholesteryl radical, a radical as defined for R* or a radical of the formula --C.sub.6 H.sub.4 --R*,and the preparation and use thereof.
    Type: Grant
    Filed: February 7, 1994
    Date of Patent: February 25, 1997
    Assignee: Consortium fur elekochemische Ind. GmbH
    Inventors: Wolfgang Haas, Norman Haberle, Rainer Winkler, Franz-Heinrich Kreuzer