Patents Examined by Sheel J. Huff
  • Antibodies that recognize the 85P1B3 protein useful in treatment and detection of cancer
    Patent number: 7217799
    Abstract: A novel gene (designated 85P1B3) and its encoded protein are described. While 85P1B3 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 85P1B3 provides a diagnostic and/or therapeutic target for cancers. The 85P1B3 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: May 15, 2007
    Assignee: Agensys, Inc.
    Inventors: Arthur B. Raitano, Mary Faris, Rene S. Hubert, Daniel E. Afar, Wangmao Ge, Pia M. Challita-Eid, Aya Jakobovits
  • Antibodies against tumor necrosis factor delta (APRIL)
    Patent number: 7189820
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to Tumor Necrosis Factor Delta (TNF-delta; APRIL). The present invention also relates to methods and compositions for detecting, diagnosing, prognosing, treating, preventing, or ameliorating a disease or disorder associated with aberrant APRIL or APRIL receptor expression or aberrant function of APRIL or APRIL receptor, comprising antibodies or fragments or variants thereof, or related molecules, that immunospecifically bind to APRIL.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: March 13, 2007
    Assignee: Human Genome Sciences, Inc.
    Inventor: Steven M. Ruben