Abstract: An ambulatory infusion pump can include a maximum bolus override procedure. When a bolus amount greater than a maximum bolus amount is requested, the ambulatory infusion pump can provide an alert indicating that the bolus amount requested exceeds the maximum bolus amount. If a user confirms the request in response to the alert, the bolus amount can be delivered to the user. The bolus amount delivered in response to the confirmation can be a first portion of the bolus amount. A reminder can then be provided that a second portion of the bolus amount that is a remaining portion of the requested bolus amount was also requested. If a second confirmation is received in response to the alert, the second portion of the bolus amount can also be delivered to the user.

Abstract: A pump system for generating a volume flow of a dialysis solution in a dialysis machine, the pump system includes at least one piston pump having a piston that cooperates with a working fluid, which exerts a force on a conveying means, and in particular on a membrane. The pump system includes setting means, with which a conveying volume of the at least one piston pump per piston stroke can be reduced, with the setting means having at least one of a position-variable mechanical piston stop to reduce the piston stroke, means to reduce a quantity of the working fluid, and means to reduce a volume of a conveying chamber that cooperates with the conveying means and that contains the dialysis solution to be conveyed.

Abstract: A medical agent delivery device may comprise a laminate of a number of layers coupled together. The medical agent delivery device may further comprise a collapsible reservoir within the laminate. The medical agent delivery device may further comprise a sharp bearing body having at least one microneedle. The medical agent delivery device may further comprise a collar element attached to the sharp bearing body. The medical agent delivery device may further comprise a removable cover assembly including a microneedle encasing body coupled to the sharp bearing body and to a release liner. The microneedle encasing body may be attached more weakly to the sharp bearing body than to the release liner.

Abstract: Methods, apparatuses, and systems for determining a peritoneal transport status of a patient based on mass analyzing low volumes of peritoneal dialysis (PD) effluent to generate patient information that may be evaluated using PD effluent fingerprints to determine peritoneal transport characteristics of the patient are described. For example, in one embodiment, a method of determining a transport status of a dialysis patient may include obtaining a volume of peritoneal dialysis (PD) effluent of the dialysis patient, generating patient information via mass analysis of the volume of PD effluent, and determining patient profile information based on evaluating the patient information with a profile library, the patient profile information comprising a peritoneal transport status classification. Other embodiments are described.

Abstract: A device may be configured to deliver an agent to a target tissue via a pressurized fluid and the device may include a catheter including a lumen; an enclosure configured to store the agent, receive the pressurized fluid, and release a combination of the pressurized fluid and the agent; and a valve downstream of the enclosure to receive the combination of the pressurized fluid and the agent from the enclosure. The valve may have a first configuration preventing a flow of the combination through the lumen and a second configuration permitting the flow of the combination through the lumen.

Abstract: A medicament delivery device has an actuation member which is movable relative to a body. The actuation member has a flexible arm comprising an engagement surface. The device has a contoured surface. When the actuation member is in a first position the engagement surface engages the contoured surface. When the actuation member moves to a second position, the flexible arm is deflected radially by the engagement of the engagement surface with the contoured surface. The device further has a blocking member. The blocking member has a proximal portion which engages the flexible arm when the blocking member is in an extended position for preventing the flexible arm from being deflected radially and moving distally. The blocking member is movable relative to the body to disengage the proximal portion from the flexible arm.

Abstract: A drug delivery device, comprising, an assembly comprising a circlip and a holding element, a device body; a medicament container comprising or adapted to comprise a medicament; wherein the circlip is configured in a deformed state to engage a surface of the medicament container in order to prevent relative movement in at least one direction of the medicament container with respect to the circlip; and wherein the holding element is configured to hold the circlip in the deformed state.

Abstract: A medicament delivery device comprises a housing, a needle, a needle cover, a needle cover biasing member, and a needle cover retaining mechanism. The needle cover is axially movable between an extended position and a retracted position. The needle cover biasing member is configured to bias the needle cover axially in a distal direction towards the extended position. The needle cover retaining mechanism is configured to be moved between a first state, in which the needle cover retaining mechanism is disengaged from the needle cover such that the needle cover is moveable in the distal direction under a force of the needle cover biasing member, and a second state, in which the needle cover retaining mechanism is configured to engage the needle cover and prevent distal movement of the needle cover under the force of the needle cover biasing member, when the needle cover is in the retracted position.

Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.

Abstract: Systems and methods for nasal irrigation are provided in which a nasal irrigation device includes a source of saline solution, an effluent receptacle, a nasal interface, a vacuum source, a fluid passageway to communicate the source of saline solution with the effluent receptacle through the nasal interface and a nasal cavity of a user, and a switch and valve assembly for selectively controlling the vacuum source and flow of the saline solution through the fluid passageway. The source of saline solution is disposed relative to the device to provide gravitational inducement of the saline solution to the nasal interface in engagement to the device user's nostrils. A combination of the gravitational inducement and a relative vacuum from the effluent receptacle generates a fluid flow for irrigating, cleansing and massaging the nasal cavity and ostia of the user. The entire device is assembled as a hand-held device for convenient lifting and disposal against the user's nostrils.

Abstract: A syringe having two variable volumes are described herein. The syringe includes a first stopper and a second stopper, the first stopper being connected to a plunger. A first variable volume of the two variable volumes is disposed between the first stopper and the second stopper and a second variable volume of the two variable volumes is between the second stopper and a distal end of a barrel of the syringe. A flow path structure is disposed at the distal end of the barrel, the flow path structure extending from the distal end of the barrel along an inner sidewall of the barrel.

Abstract: A fluid handling cassette, such as that useable with an automated peritoneal dialysis (APD) cycler device or other infusion apparatus, may include a generally planar body having at least one pump chamber formed as a depression in a first side of the body and a plurality of flowpaths for a fluid that includes a channel. A patient line port may be arranged for connection to a patient line and be in fluid communication with the at least one pump chamber via at least a first one of said flowpaths, and an optional membrane may be attached to the first side of the body over the at least one pump chamber. In one embodiment, the membrane may have a pump chamber portion with an unstressed shape that generally conforms to the depression of the at least one pump chamber in the body and is arranged to be movable for movement of the fluid in a useable space of the at least one pump chamber.

Abstract: The present disclosure concerns embodiments of multi-lumen cannulae that can be used in various different medical procedures. The multi-lumen cannulae can comprise an elongated body comprising multiple different ports that connect to various different sidewall lumens contained within the elongated body. The multi-lumen cannulae can also comprise a central lumen that extends through the entire elongated body and can be fluidly connected to the various different sidewall lumens. The multi-lumen cannulae can further comprise two balloons on an exterior of the elongated body, which can be used to isolate a right atrium of a patient's heart.

Abstract: A device for administering a fluid is provided, with a cylinder (16, 116) which has an open dispensing end (17), a piston (36) which is displaceable between a front end position and a rear end position in the cylinder (16, 116) and is connected to a piston rod (35, 135) that protrudes along a first direction beyond a rear end of the cylinder (16, 116) opposite the open dispensing end (17) and is guided in a receiving block (10), a nonreturn valve (18) closing the open dispensing end (17), and a tensioning device (S) which is connected to the piston rod (35, 135) and is arranged in the receiving block (10), wherein the tensioning device (S), when the piston (36) is in the front end position, can move the piston rod (35, 135) in a tensioning operation along the first direction until the piston (36) is in the rear end position in order thereby to fill the cylinder (16, 116) with the fluid to be administered and in order to pretension the piston rod (35, 135) toward the open dispensing end (17), and wherein th

Abstract: An inflatable port including a housing, a chamber in the housing, a septum over the chamber, a hollow stem extending from the housing, and a bladder around at least a portion of the housing. The chamber has a major opening and a minor opening. The septum is positioned over the major opening of the chamber and is fixed to the housing. The stem fluidly connects to the chamber by way of the minor opening of the chamber. The bladder is configured to increase a size of the inflatable port upon inflation of the bladder and decrease the size of the inflatable port upon deflation of the bladder. Also disclosed herein is a catheter assembly including the inflatable port, as well as a method related to the inflatable port and the catheter assembly.

Abstract: A patient care system has a medical pump for delivering a medicine to a patient, and a processor in communication with the pump. The pump is configured to receive a first input on whether the medicine is a critical medicine, and a second input on a trigger condition that triggers a fail-operate mode for the critical medicine. The processor controls the medical pump to operate in the fail-operate mode, where the fail-operate mode continues delivery of the critical medicine when the trigger condition is triggered.

Abstract: A syringe includes a syringe body, a first plunger, a second plunger, and an inner tube. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger is disposed within the syringe cavity and defines a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The second plunger is disposed within the syringe cavity, the first plunger and the second plunger cooperatively defining a second chamber in the syringe cavity. The inner tube comprises an inner tube lumen, wherein the inner tube and a first plunger shaft lumen of a first plunger shaft define an annulus therebetween, the annulus in fluid communication with a first plunger channel of the first plunger and the annulus permits fluid communication between the syringe port and the first plunger channel.

Abstract: Implementations of a present disclosure are directed to a drug delivery device including a reservoir, a stopper, and a light emitting-detecting system. The reservoir includes a wall defining a proximal end and a distal end. The stopper includes an optically reflecting element. The stopper is configured to expel a portion of a medicament stored within the reservoir by moving within the reservoir in a direction from the distal end to the proximal end, such that a stopper position is indicative of an amount of the medicament within the reservoir. A light emitting system of the light emitting-detecting system is configured to provide a light signal towards the stopper from the distal end. A light detecting system of the light emitting-detecting system is configured to detect a reflected light signal provided by a reflection of the light signal on the optically reflecting element of the stopper and to provide an electric signal in response to detecting the reflected light signal.

Abstract: A medicament delivery device for reducing a force required to activate the device includes a needle disposed at a distal end of the device, a needle cover, and a body. The needle cover is axially movable relative to the body between an initial position in which the needle cover covers the needle and an activated position for dispensing a medicament. The needle protrudes from a distal end of the needle cover when the needle cover is in the activated position. The medicament delivery device includes a carrier configured to support a syringe. The carrier is disposed within the needle cover and includes a deformable element configured to change from a first configuration in which the deformable element is engaged with the needle cover to a second configuration in which the deformable element is not engaged with the needle cover.

Abstract: A catheter assembly (10) comprises a catheter (20), a needle (22) having a sharp distal tip and disposed within the catheter (20), a catheter hub (30) connected to the catheter (20) having the needle (22) passing therethrough, and a housing (70) that encloses the sharp distal tip of the needle (22). An external surface of the catheter hub (30) and an internal surface of the housing (70) each include at least one of a channel member (34) and a raised portion (72) that interfit to restrict motion between the catheter hub (30) and the housing (70).