Abstract: There is provided a topical composition and method for improving the aesthetic appearance of skin, particularly, preventing, ameliorating, treating and/or reducing fine lines and/or wrinkles, without the skin irritation typically associated with topical application of a retinoid. There is also provided a topical composition and method for improving the aesthetic appearance of lips, particularly decreasing the number and/or depth of vertical lip lines. The composition has an effective amount of retinoxytrimethylsilane. Preferably, the composition is applied daily to skin and/or lips. The composition and method are particularly suitable for persons having sensitive skin.

Abstract: A stable aluminum-zirconium aqueous solution of enhanced efficacy having a high concentration free of amino acid and polyhydric alcohol is disclosed. Such aluminum-zirconium salts are selected from aluminum/zirconium tetrachlorohydrate; aluminum/zirconium pentachlorohydrate, and aluminum/zirconium octachlorohydrate in which the aluminum to zirconium (Al/Zr) atomic ratio of said salt falls within the limits of the shaded areas A, B, and C, respectively, of the drawing graph wherein the aluminum/zirconium tetrachlorohydrate has an Al/Zr atomic ratio from about 2 to about 6 and metal/chloride molecular ratio about 0.9 to about 1.25; aluminum/zirconium pentachlorohydrate having Al/Zr atomic ratio from about 6 to about 10 and metal/chloride atomic ratio from about 1.5 to about 1.65; and aluminum/zirconium octachlorohydrate having Al/Zr molecular ratio from about 6 to about 10 and metal/chloride molecular ratio from about 0.9 to about 1.5.

Abstract: The present invention relates to novel pharmaceutical compositions of bimatoprost and other cyclopentane(ene) heptan(en)oic acid amides and their use in preventing sunburn and/or providing an artificial tan to human skin.

Abstract: The invention is a light-protective cosmetic or dermatological preparation comprising (a) at least one water-soluble UV-filter substance and (b) at least one benzoxazole derivative. The invention is also a cosmetic or dermatological preparation comprising at least one water-soluble UV-filter substance and at least one benzoxazole derivative of a specified chemical structure. The invention is also a method of treating or preventing cosmetic or dermatological changes in the skin, a method of tanning or accelerating tanning of the skin, and a method of protecting the skin against light-induced aging, each comprising applying the cosmetic or dermatological preparation to the skin. The invention also includes a wipe impregnated with the preparation.

Abstract: A novel efficacious and less irritant aluminum-zirconium antiperspirant composition is provided by the addition of a small amount of AlCl3 and/or HCl to the activated aluminum component. After the heating of diluted basic aluminum chlorohydrate solution, cooling to room temperature, mixing with small amount of AlCl3 or HCl and then reacting with zirconium glycine complex, an aluminum-zirconium salt is produced with a maximum amount of depolymerization aluminum and zirconium species. The addition of a small amount of AlCl3 or HCl to the diluted and activated aluminum chlorohydrate solution accelerates the depolymerization of the activated ACH solution, and upon the addition of zirconium glycinate the solution is further depolymerized and results in the formation of less polymerized zirconium species.

Abstract: The present invention includes a process of preparing an advanced cosmetic product by combining a high internal phase ratio (HIPR) emollient-in-water emulsion with a partial cosmetic formulation that typically contains water, a coloring agent, a fragrance, a rheology modifier, or a pH adjuster, or a combination thereof. The present invention also includes compositions directed to two particular subclasses of HIPR emollient-in-water emulsions, namely an HIPR silicone elastomer-in-water emulsion and an HIPR sunscreen-in-water emulsion and water-diluted dispersions thereof. The use of an HIPR emulsion of a cosmetic emollient provides a simple and flexible method of formulating the cosmetic product, due in part to the long shelf-stability of the HIPR emulsion (greater than 1 year), and the low quantity of water in the emulsion (typically less than 20% by volume based on the volume of emollient and water).

Abstract: Photoprotective cosmetic/dermatological compositions well suited for the UV-photoprotection of human skin and/or hair, comprise (a) particulates of at least one insoluble mineral and/or organic UV-screening agent having a particle size ranging from 5 nm to 5 ?m and (b) a stabilizing amount of at least one amphiphilic polymerizate of at least one ethylenically unsaturated monomer which comprises a sulfonic group, whether in the free acid or in partially or totally neutralized state, and which amphiphilic polymerizate also comprises at least one hydrophobic moiety.

Abstract: Dispersions containing from about 0.5% to about 30% by weight dispersed microfine calcined alumina, stainless steel, or gold particles typically having particle size of less than about 5?, more narrowly 1? or less, suspended in a cosmetically acceptable carrier are useful as sunblocks for skin and hair while simultaneously providing treatments that render skin and hair smoother, more uniform, lustrous, visually appealing and healthier-looking.

Abstract: The invention encompasses additives for addition to a composition for topical application, e.g., a bodywash, where the additive contains an encapsulated non-sunscreen, and methods of making and using the additives as well as topical compositions containing the additives. The additive may be encapsulated in a sol-gel microcapsule, and, in some cases, also includes a cationic polymer.

Abstract: Disclosed are anhydrous antiperspirant and deodorant compositions that comprise from about 0.1% to about 30% by weight of an antiperspirant or deodorant active; from about 0.01% to about 20% by weight of a solid, water-soluble Vitamin B3 material; from about 0.1% to about 40% by weight of a suspending agent; from about 0.1% to about 2.0% by weight of glycerin; and from about 10% to about 99% by weight of an anhydrous carrier liquid other than and in addition to the glycerin. The anhydrous compositions have lower visible residue on the applied areas of the skin even though they also contain relatively high residue solids in the form of solid, water-soluble, Vitamin B3 materials. The compositions also provide for a dry, silky feeling during or after application.

Abstract: An in vitro method for the prediction of in vivo UVA protection by a composition with sunscreen properties. The method includes the steps of: determining in vivo SPF; determining in vitro SPF based on the sunscreen's absorbance spectrum in the UV region; normalizing the absorbence spectrum based on integration area of UVA1; and calculating the PFA-PPD in vitro.

Abstract: The invention is a light-protective cosmetic or dermatological preparation, comprising (a) at least benzotriazole and (b) at least one benzoxazole derivative. The invention is also a cosmetic or dermatological preparation comprising at least one benzotriazole from a select group and at least one benzoxazole derivative of a specified chemical structure. The invention is also a method of treating or preventing cosmetic or dermatological changes in the skin, a method of tanning or accelerating tanning of the skin, and a method of protecting the skin against light-induced aging, each comprising applying the preparation to the skin. The invention also includes a wipe impregnated with the preparation.

Abstract: The invention encompasses methods of use of bodywashes containing additive to modify skin, e.g., protection of skin from sunlight by application of a bodywash containing a sunscreen. Thus, in one aspect, the invention provides a method for protection of skin from sunlight by applying a bodywash comprising a sunscreen to the skin, where after application of the bodywash to skin and rinsing, the skin is protected from sunlight with an average SPF of at least about 15.

Abstract: Topically applicable, non-pilling UV-photoprotecting cosmetic/dermatological sunscreen compositions, advantageously alcoholic sunscreen gels, well suited for UV-photoprotecting human skin and/or hair against the damaging and deleterious effects of ultraviolet irradiation, contain an effective amount of at least one UV-A and/or UV-B screening agent and an effective non-pilling amount of an acrylates/C12-22 alkylmethacrylate copolymer, preferably a tetrapolymer of methacrylic acid, methyl methacrylate, butyl acrylate and cetyl-eicosinyl methacrylate, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Abstract: The present invention relates generally to the use of vitamin B12 (cobalamin or cyanocobalamin) alone or in combination with other photoprotective agents, including specifically other vitamins such as vitamin B9 (folic acid or folate) and vitamin B3 (niacin or niacinamide), or any chemical derivative of these vitamins and their salts, as a filter to protect cells against the damaging effects of ultraviolet (UV) light. The invention is, in one aspect, a method of reducing the rate of UV damage to cells exposed to a UV light source, by treating the cells with the vitamin composition, either alone or in combination with other photoprotective agents.

Abstract: Disclosed are aqueous antiperspirant active compositions comprising an admixtures of basic aluminum halides and a metal cation salts which yield enhanced antiperspirant efficacy; and methods of making such antiperspirant compositions. The basic aluminum halides, optionally contain an amino acid or salts of amino acids, and/or antimicrobial agent and are combined with a metal cation antiperspirant (e.g., Ti salt or Hf salt or Sn salt or Zr salt) and optionally with a organic solvent having at least two carbon atoms and at least one hydroxy group and mixtures thereof and methods of making such mixtures. Basic aluminum halides having enhanced antiperspirant efficacy are produced by reacting (a) aluminum powder; (b) an aluminum halide; and (c) water at a temperature greater than about 85° C. This reaction is maintained until reaction products having an Al:halide ratio of about 1.2 to 1.5 and preferably 1.3 to 1.

Abstract: There is provided a composition comprising one or more photoactive compounds and one or more optimization agents. Surprisingly, the composition requires a small amount of optimization agent to efficiently optimize the polarity, critical wavelength, SPF, PFA, Star Rating, photostability, or any combinations thereof, of the composition. Subsequently, an efficient sunscreen composition is achieved.

Abstract: Compositions and methods of using the compositions to achieve a therapeutic effect are provided.

Abstract: This invention relates to new dermocosmetic and pharmaceutical compositions which are useful for improving and treating hyperreactive skin conditions and more generally allergic-type reactions and/or intolerance phenomena, whether they are caused by external factors or factors intrinsic to the individual. The compositions of this invention preferably contain an anti-radical, in anti-inflammatory and an anti-allergic activity for the treatment of sensitive and/or allergic skin.

Abstract: The invention concerns relates to the use of an efficient amount of lipochroman-6, in a physiologically acceptable medium, in a composition or for preparing a composition, the lipochroman-6 or the composition being designed to inhibit NO-synthase.