Abstract: The present invention is concerned with physicochemically stable aqueous solutions of risperidone for oral administration which do not contain sorbitol.

Abstract: Polyphosphonic acid ester compounds with flavorant, coolant and/or sweetener components, and tartar, plaque and/or calculus control compositions with improved taste comprising one or more polyphosphonic acid ester compounds are described.

Abstract: The present invention provides a method of improving the efficiency of absorption into the bloodstream of drugs delivered through the pulmonary route. The drug is mixed with surfactant, preferably a surfactant naturally produced by the lung. This method is found to enhance the absorption of pharmaceutical compositions, and in particular those comprising protein, eg insulin, or peptides, eg vasopressin.

Abstract: An oral hygiene composition for use in the treatment of dentine hypersensitivity comprises a water soluble strontium salt and a water soluble potassium salt, together with a dentally acceptable excipient. Preferably, the composition is in the form of a dentifrice comprising an abrasive silica and a thickening silica, and optionally includes an ionic fluorine-containing compound.

Abstract: The inventor found for the first time that an extracted material from coral sand occurring in nature contains physiological activating substances. Based on this observation, in a process according to the present invention, physiological activating substances are extracted from coral sand by an appropriate extraction method. The extracted physiological activating substances are used as ingredients of cosmetics, food, and medicines. According to the present invention, physiological activating substances can be extracted in an industrially available form.

Abstract: Disclosed are oral compositions which are effective against plaque and gingivitis and contain a noncationic water insoluble antibacterial agent.

Abstract: The invention relates to cardiology, and provides an antihypoxic formulation, Energostim, including cytochrome C, nicotinamide adenine dinucleotide and inosine.Energostim provides a complete normalization of energy metabolism and the recovery of oxygene deficiency in heart, brain, liver and other internals.

Abstract: Oral compositions, such as oral gels, toothpastes and mouthwashes, containing an enzyme, a surfactant, a chelating agent, a fluoride ion source and wherein the pH of the composition is from about 4.0 to about below 6.0.

Abstract: A topical agent and method for the treatment and prevention of pseudofolliculitis barbae, related secondary bacterial infections and other skin conditions associated with shaving result from a combination of three ingredients, namely benzoyl peroxide, camphor oil and aloe vera present in 15:4:1 parts by volume of the composition, respectively.

Abstract: Oral compositions, such as oral gels, toothpastes and mouthwashes, containing an enzyme, a surfactant, a chelating agent and a fluoride ion source.

Abstract: New medicament aerosol formulation based on fusafungine comprising excipient which is either dimethyl isosorbide or preferably, isopropyl myristate, and using as propellant 1,1,1,2-tetrafluoroethane.

Abstract: Dental caries are prevented by contacting teeth with an edible composition containing micellar casein which has been isolated from an animal milk and which is incorporated in the composition in an amount sufficient to inhibit oral colonization by Streptococcus sobrinus.

Abstract: An antifungal agent for the treatment of skin disease such as athlete's foot, ringworm and tinea caused by dermatophytes, eczema, tinea or various fungi, which comprises a 100 weight % of detergent solution including 0.01-40 weight % of sodium hypochlorite, 0.01-30 weight % of sodium sulfite, 0.01-40 weight % of sodium nitrite, 0.01-40 weight % of sodium chlorate, 0.01-40 weight % of potassium chlorate, 0.001-35 weight % of hydrogen peroxide, 0.01-40 weight % of ozone water, 0.01-40 weight % of sodium nitrite, 0.01-40 weight % of potassium nitrite, 0.001-1 weight % of nonionic surface active agent and 1-90 weight % of water.It is characterized in that trichophyton, eczema or various fungi in the dermis or deep layer are allured by oxygen contained in the antifungal agent to or near the surface of the skin for easy sterilization by oxidation, reduction, bleaching and fungicidal activity.A ligand agent is also efficacious for the treatment of a burn of the skin and of stiffness in the shoulder.

Abstract: Dental floss having a wax or similar caoting impregnated with a nascent oxygen generating agent such as calcium peroxide.

Abstract: A dentifrice which inhibits plaque formation and reduces gingivitis and caries comprising water-insoluble alkaline earth metal polishing agent such as dicalcium or dimagnesium phosphate or pyrophosphate, xylitol and a substantially water insoluble noncationic antibacterial agent, such as triclosan.

Abstract: The present invention provides a method of treating a female in need of hormone replacement therapy comprising transdermally administering to said female a series of alternating phases of from about one to about four days of estrogen dominant activity and phases of from about one to about four days of progestin dominant activity, with the estrogen dominant activity phase consisting of administering a transdermal estrogen substance alone or administering a transdermal estrogen substance and a transdermal progestin substance and the progestin dominant activity phase consisting of administering a transdermal progestin substance and a transdermal estrogen substance, the amount of progestin substance being alternately increased in the progestin dominant activity phase and decreased in the estrogen dominant activity phase to provide the required dominant activity.

Abstract: The invention is directed to a method for the modification of the rate of release of a drug from a hydrogel which is based on the use of an effective amount of a pharmaceutically acceptable ionizable compound that is capable of providing a substantially zero-order release rate of drug from the hydrogel.

Abstract: The present invention relates to a pharmaceutical composition for use in treatment of cancer patients. The composition includes at least one taxane present in a pharmaceutical effective amount and a mixture of one or more negatively charged phospholipids and one or more zwitterion (i.e. uncharged) phospholipids. This mixture entraps the at least one taxane in what is believed to be a liposome. The mixture contains a ratio of negatively charged phospholipids to zwitterion phospholipids of 1:9 to 7:3. The taxol is present in an amount of 1.5-8.0 mole percent taxane. The composition is in the form of particles having a size of 0.025 to 10 microns with substantially no taxane crystals.

Abstract: This invention relates to a vascular hypertrophy inhibitor containing a compound of the formula ##STR1## or its pharmaceutically acceptable salt as an active ingredient. This composition produces excellent effects as a vascular hypertrophy inhibitor.

Abstract: The present application features methods and articles of manufacture for alleviating acute symptoms of nicotine withdrawal and as an aid in smoking cessation. The invention features lobeline held in sublingual tablets for administration to the sublingual and nasal mucosa.