Abstract: It was found that if a copolymer of maleic acid or maleic anhydride with an alkyl vinyl ether, which has a specific viscosity of 3.5 or more, is used as an antibacterial-enhancing agent, the action of an antibacterial agent in an oral composition is enhanced and the effect such as adhesion prevention of a soft deposit is improved.

Abstract: The present invention relates to a dry type tooth whitening patch comprising peroxide as a tooth whitening agent. In particular, disclosed is a dry type tooth whitening patch in which a peroxide is contained, as a teeth whitening agent, in a matrix type adhesive layer. The adhesive layer includes, as a base polymer thereof, a hydrophilic glass polymer which provides a strong adhesion to teeth while releasing the tooth whitening agent when hydrated on the enamel layers of teeth in the moist oral cavity. The dry type patch according to the present invention is convenient in use, as compared to wet type patches. Further, it exhibits a superior adhesion while being maintained in a state attached to the teeth for a lengthened period of time so as to assure an enough contact time between the whitening agent in the patch and stains on the teeth, thereby giving a sufficient whitening effect.

Abstract: An abrasive, amorphous precipitated silica is provided that provides excellent abrasive performance, but also has a relatively high degree of transmittance, and an index of refraction that is sufficiently low to allow it to be a component of a transparent toothpaste composition having a relatively high concentration of water. The amorphous precipitated silica composition has a refractive index of less than about 1.4387, a light transmittance of greater than about 48%; and a Brass Einlehner abrasion value of greater than about 5 mg loss/100,000 rev. A dentifrice having a haze value of less than about 70 may be prepared using this abrasive, amorphous silica.

Abstract: The invention relates to a method and a preparation for cleaning tooth root surfaces and surrounding tissue (periodontal pockets). The preparation is a two-component liquid of the type that has previously been used for chemical-mechanical treatment of carious lesion. The active component in the liquid is a hypochlorite, preferably sodium hypochlorite, and the other component in the liquid is a component which reduces the aggressiveness of the hypochlorite on healthy tissue and which also increases the viscosity of the liquid. The preparation is applied on the tooth root surface in question by means of a brush or an applicator instrument. After 10-15 seconds the root surface is cleaned by means of a scraping instrument.

Abstract: Mupirocin or a salt or ester thereof may be used to treat recurrent sinusitis and recurrent otitis, in particular with novel spray or cream formulations adapted for administration to the nasopharynx.

Abstract: A method for enhancing the antiplaque efficacy of an antibacterial dentifrice, comprising preparing a multicomponent dentifrice composition having a first dentifrice component containing an antibacterial agent and manganese coordination complex compound, and a second dentifrice component containing a peroxide compound; maintaining the first and second dentifrice components separately prior to use; combining the dentifrice components and applying the two components to the teeth and periodontium, whereby the dentifrice provides enhanced inhibition of plaque growth.

Abstract: A dentifrice composition comprising a liquid polyalkylene glycol carrier, and a liquid polyoxyalkylene compound miscible in said liquid polyalkylene glycol carrier.

Abstract: A SnF.sub.2 gel composition exhibiting improved stand-up and stability to exposure to air containing moisture which composition contains SNF.sub.2, anhydrous glycerin, a polyethylene glycol having an average molecular weight of 1000 and xanthan gum.

Abstract: A toothpaste for smokers for solubilizing and removing cigarette tar deposits on the teeth, gums, tongue, other surfaces of the oral cavity, and dentures of smokers including at least one nonionic surfactant in a concentration range of from about 0.3% to about 6.5% by weight, methyl salicylate in a tobacco tar solubilizing concentration range of from about 0.06% to about 0.20% by weight, at least one essential oil in a concentration range of from about 0.30% to about 2.0% by weight, ethyl alcohol in a concentration range of from about 12.0% to about 20.0% by weight, at least one anionic surfactant in a concentration range of from about 0.3% to about 4.5% by weight, and a gelling agent.

Abstract: Oral compositions, such as oral gels, toothpastes and mouthwashes, containing a chelating agent and a hydrophobic anionic surfactant.

Abstract: This invention is concerned with a contraceptive formulation and a method of contraception which employs a combination of estrogen and progestin and wherein a short period of relatively dominant estrogenic activity alternates with a short period of relatively dominant progestagenic activity. The invention also concerns a hormonal replacement formulation and method for use in menopausal or castrate women which employs a similar combination of estrogen and progestin.

Abstract: A process for reducing precipitation of difficultly soluble pharmaceutical active in a mixture of polyethylene glycol, polyvinylpyrrolidone and propylene glycol.

Abstract: An antifungal agent for the treatment of skin disease such as athlete's foot, ringworm and tinea caused by dermatophytes, eczema, tinea or various fungi, which comprises a 100 weight % of detergent solution including 0.01-40 weight % of sodium hypochlorite, 0.01-30 weight % of sodium sulfite, 0.01-40 weight % of sodium nitrite, 0.01-40 weight % of sodium chlorate, 0.01-40 weight % of potassium chlorate, 0.001-35 weight % of hydrogen peroxide, 0.01-40 weight % of ozone water, 0.01-40 weight % of sodium nitrite, 0.01-40 weight % of potassium nitrite, 0.001-1 weight % of nonionic surface active agent and 1-90 weight % of water.It is characterized in that trichophyton, eczema or various fungi in the dermis or deep layer are allured by oxygen contained in the antifungal agent to or near the surface of the skin for easy sterilization by oxidation, reduction, bleaching and fungicidal activity.A liquid agent is also efficacious for the treatment of a burn of the skin and of stiffness in the shoulders.

Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.

Abstract: Bioadhesive pharmaceutical carrier consisting essentially of a polymer blend of sodium carboxymethyl cellulose and xanthan gum or sodium alginate. The invention also provides for a method of control releasing a pharmaceutical active comprising incorporating an active into the bioadhesive pharmaceutical carrier. The invention is particularly adaptable for oral use and teething gels.

Abstract: The subject invention relates to methods and compositions comprising: a) from about 0.1% to about 5% of a compound having the structure selected from the group consisting of: ##STR1## wherein each R is independently selected from the group consisting of hydrogen, alkyl, and aryl; each R' is independently selected from the group consisting of hydrogen, alkoxy, and alkyl; Z and Z' are independently selected from the group consisting of NH, O, and CH.sub.2 such that when Z or Z' is NH, the other is not O; or a pharmaceutically acceptable salt of any of the aforementioned compounds; and b) a pharmaceutically-acceptable topical carrier.

Abstract: The present application is directed to oral hygiene agents, a process for their preparation, and the use of a hydrogen peroxide solution stabilized by a silver colloid in concentrations of from 0.1 to 10% by weight, preferably from 1 to 3% by weight, in oral hygiene agents.

Abstract: The invention disclosed relates to the use of dimethicone as an agent for treating constipation.

Abstract: The present invention relates to a composition and a galenic formulation suitable for combatting affections of the lower abdomen, for example intestinal conditions such as diarrhea, said composition or formulation containing:(a) an effective amount of a compound of formula I ##STR1## (b) at least one wetting agent, and preferably (c) a starch derivative.

Abstract: This application discloses a method of inhibiting degradation of the antidepressant bupropion hydrochloride in a solid pharmaceutical formulation, so that the pharmaceutical formulation will maintain at least 80% of its initial bupropion potency after one year.