Abstract: A method and device for delivering a therapy in response to detection of abnormal cardiac rhythms that includes a first circuit delivering a first therapy and a second circuit delivering a second therapy, the second circuit including an energy storage device for storing energy associated with the second therapy and a charging circuit selectively coupled to the storage device to generate the stored energy. A control circuit controls the first circuit and the second circuit to deliver the first therapy substantially simultaneous with the charging of the energy storage device in response to the predetermined event being detected, and decouples the energy storage device from the charging circuit during a redetect period subsequent to delivery of the first therapy. The control circuit recouples the energy storage device and the charging circuit in response to the microprocessor detecting the predetermined event during the redetect period.

Abstract: An oxygen monitoring system measures the oxygen concentration in a patient's blood for use as a physiological control parameter in rate responsive pacing. The oxygen monitoring system includes an oxygen monitoring circuit embedded in a cardiac stimulation lead and monitors the blood oxygen in a patient's venous system that passes through and into the lead. The oxygen monitoring circuit includes a working electrode, a counter electrode, a reference electrode and an IC chip electrically interconnected between the electrodes and programmed to carry out an oxygen concentration measuring process. Oxygen surrounding the electrodes causes current to flow between the electrodes and the IC chip varies the value of current generated by a current source coupled between the working electrode and counter electrode in a manner to maintain the voltage between the working electrode and reference electrode at a preselected value. The variation of the current source value is a direct measure of the blood oxygen concentration.

Abstract: A portable device for applying therapeutic electrical signals and/or electromagnetic fields to a patient's knee for the treatment of osteoarthritis and other diseases, defects and injuries. The device is operable in several modes to deliver signals to the patients knee so as to cause an electric and/or electromagnetic field to be generated that selectively up-regulates gene expression of Aggrecan and Type II Collagen while simultaneously selectively down-regulating the gene expression of metalloproteases. The device includes a signal generator that generates compound electric signals including a 60 kHz sine wave having a peak to peak voltage of approximately 4.6 V to 7.6 V and a 100% duty cycle signal that is generated for approximately 30 minutes and a 50% duty cycle signal that is generated for approximately 1 hour after the 100% duty cycle signal.

Abstract: In an atrial pacing system, the A-PACE pulse energy, defined by the pulse width and pulse amplitude, sufficient to reliably capture the atrium without being wasteful of battery energy is periodically determined in accordance with atrial capture management (ACM) algorithms. The ACM algorithms allow a slow intrinsic atrial heart rate that is suppressed by delivered A-PACE pulses resulting in A-CAPTURE and that occurs when delivered test A-PACE pulses result in ALOC to be detected. ALOC is declared if an A-EVENT of the slow intrinsic atrial heart rate is detected either during an ACM test window timed from the last delivered test A-PACE pulse or during delivery of a sequence of test A-PACE pulses delivered within or defining the ACM test window correlated to the slow intrinsic atrial heart rate.

Abstract: A medical lead adapter assembly is provided for facilitating an electrical connection between an implantable medical lead connector and an external medical device. The adapter includes a housing, having a sidewall and a longitudinally extending connector receptacle, and at least one contact opening passing through the sidewall to the receptacle. The contact opening is positioned in a location corresponding with at least one ring contact of the lead connector, when the lead connector is engaged within the receptacle, and allows electrical connection between at least one contact element of the external medical device and the at least one ring contact of the lead connector.

Abstract: An implantable medical device having a case with therapeutic componentry contained with the case. A module has a rail around at least a portion of a perimeter of the module and is adapted to be mechanically secured to the case. The case has a rigid fastening channel adapted to receive the rail of the module. The rigid fastening channel has an opening allowing the rail of the module to drop into the rigid fastening channel through the opening and then slide along the rigid fastening channel to be mechanically secured to the case.

Abstract: Neuromuscular stimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles or nerves inside the body and stimulus generators or recording instruments mounted on the surface of the skin outside the body.

Abstract: A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal and a patient alarm is further provided and electrically coupled to the electrical signal processor. The patient alarm generates an escalating sensory alarm signal over a predetermined time period subsequent to the electrical signal processor if the processor detects a cardiac event. The patient alarm may be further applied to a pacemaker or defibrillator system.

Abstract: An epicardial electrode which is suitable, in particular, for use with a cardiac stimulation device, comprises an electrode body which has a stimulation surface adapted to bear against the cardiac tissue and to stimulate a part of the heart, that is to say a partial region of the heart, and at least one fixing element for fixing the stimulation surface to the cardiac tissue. The at least one fixing element is adapted for engagement into the cardiac tissue. The epicardial electrode can be secured to the outside and in particular to the outer skin of the cardiac muscle (epicardium) without being sewn to the cardiac muscle like a patch electrode. Only the fixing element has to be brought into engagement with the cardiac tissue.

Abstract: Systems and methods that improving the specificity of discriminating between a monomorphic tachyarrhythmia and a polymorphic tachyarrhythmia are provided that examine frequency content and baseline information of the EGM as discriminatory signatures. Particular algorithms of the present invention that are employed to determine frequency content of the QRS complexes are titled the Slope Distribution Metric (SDM) algorithm and the Slope Distribution Composite (SDC) algorithm.

Abstract: The housing of an implantable cardiac device is selectively made active or passive by an external connector member, such as a shorting plug or lead connector inserted in its header. Advantageously, the header, the shorting plug, and the lead connector all are constructed and arranged to conform to a pre-selected standard in the industry, such as IS-4. The header includes an access hole that is provided with several housing connector elements connected either to the conductive surface or to an internal electrical circuit. The external connector members each have a shaft with external conductor elements. Each shaft includes conductors such as wires. The housing is made active by inserting into the header an external connector element having two of its external connector elements connected by a shorting wire.

Abstract: An improved human motion applicator assures a quick and sufficient amount of displacement given to a part of a human body. The applicator includes a support adapted to be fitted on the part of the human body. The support carries at least one electro-active elastic actuator in a force-transmitting relation to the human part. The actuator includes a dielectric core and a pair of electrodes on opposite of the core for receiving a driving DC voltage thereacross. The elastic actuator has a length and elastically deforms in the lengthwise direction to exert a stretching force to the human part to a greater extent as the driving DC voltage increase. The applicator also includes a controller which applies the driving DC voltage of varying levels to the elastic actuator, thereby generating a varying motion-inducing force to be applied to the part of the human body.

Abstract: Systems and methods of verifying that implantable cardiac devices operate as intended in a particular patient involve one or more of determining proper placement of system components, determining stimulus levels useful for individual patient stratification, and determining stimulus levels that indicate efficacy of devices, implantable within a given patient. A pacing stimulus set at a surface pacing level is delivered to a patient's heart using surface electrodes. The patient is determined to not be a candidate for implantation of a subcutaneous defibrillation system if the surface pacing level needed to capture the heart exceeds a predetermined level. The patient may be determined to be a candidate for implantation of a subcutaneous system if the surface pacing level needed to effect capture is within an acceptance level. Such determinations are preferably based on a proportionality relationship between a subcutaneous defibrillation level and a surface pacing level.

Abstract: Pathological conditions are alleviated by bone conduction practiced by the application of sinusoidal electric waves at frequencies of between 4,200 and 6,500 hertz at less than 200 microamperes current.

Abstract: A cardiac rhythm management apparatus may include a monitored energy source, a reference energy source, and a measurement module. The monitored source provides an initial pacing amplitude voltage and a pacing droop voltage, while the reference source provides a substantially fixed reference voltage. The measurement module, coupled to the monitored source and the reference source, provides a measurement related to the lead impedance associated with the rhythm management apparatus that is substantially independent of the reference voltage. Thus, a system may include the apparatus coupled to a lead wire. An article may cause a machine to implement a method which operates to determine a ratio of the actual initial pacing amplitude voltage to the actual pacing droop voltage.

Abstract: A programming-device user interface may include multiple levels of abstraction for programming treatment settings. A stimulation zone-programming interface may be at a highest level of abstraction and may include idealized stimulation zones. A field strength-programming interface may be at a middle level of abstraction and may include electromagnetic field-strength patterns generated by the stimulation zones, and/or electrode settings, and a depiction of how the electromagnetic fields interact with each other. An electrode-programming interface may be at a lowest level of abstraction and may depict treatment settings at an electrodes-view level. These interfaces may include a display of a stimulatable area of the patient's body. The display may include a depiction of leads and/or the underlying physiology, such as a depiction of a portion of a spine. Algorithms map treatment settings from one level of abstraction to settings at one or more other levels of abstraction.