Abstract: Provided is a genome extraction device to which a dual chamber structure of an outer chamber and a bead chamber is applied, more particularly a genome extraction device to which the above-described dual chamber structure is applied so that the performance of dry beads vulnerable to moisture can be maintained for a long time.

Abstract: Disclosed are methods and devices for interfacing to or interacting with the flow of liquid passing into or through lateral-flow assays and related paper- or membrane-based in-vitro diagnostic testing platforms. This is done for the purpose of improving their performance, sensitivity, accuracy, repeatability, degree of multiplexing, and/or level of quantitation, and/or reducing their inherent limitations while maintaining, in large part, their simplicity, cost effectiveness, and ease of use. New methods are disclosed for pre-sample purification, aliquoting, sequential liquid delivery, flow control and other functions that are largely automatic and require no action on the part of the user.

Abstract: The present disclosure relates to retractable diagnostic devices, and hybrid diagnostic devices comprised of water-dispersible, flushable, biodegradable, or water-soluble material and non-water-dispersible, non-flushable, or non-water-soluble material.

Abstract: A pneumatic driver for a syringe is provided. The syringe has an elongated barrel with a cap secured to the proximal end that has a through bore. A filter is secured to the cap interior of the barrel that covers an opening in the through bore interior of the barrel. The pneumatic driver includes a source of pressurized air; a support for receiving and locating the syringe; and a supply block configured to receive pressurized air from the source and having an outlet for delivery of pressurized air. The supply block is movable between a first position spaced apart from the cap of the syringe and a second position in contact with the cap with fluid communication being established between the outlet of the supply block and the through-bore in the cap.

Abstract: The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

Abstract: The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

Abstract: The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

Abstract: Sensor clip assemblies, sensor clips, analyte testing systems, and methods for making and using the same are disclosed. A sensor clip assembly is disclosed for storing and dispensing analyte testing sensors. The sensor clip assembly includes numerous test sensors arranged in a stack. Each test sensor is configured to assist in testing an analyte in a fluid sample. The sensor clip assembly also includes a skeletal frame with a top, a bottom, and numerous sides. The top, bottom and sides are interconnected to define an internal chamber within which is stored the stack of test sensors. At least one of the sides includes one or more elongated rails with structural gaps on opposing sides thereof. For some configurations, multiple sides of the skeletal frame comprise at least one or multiple elongated rails, each of which has structural gaps on opposing sides thereof and may be columnar in nature.

Abstract: A system for detecting COVID-19 infection, including a colorimetric sensor, an image-capturing device, and a processing unit connected to the image-capturing device. The colorimetric sensor includes an injection zone and a detection zone patterned on a paper, where the injection zone covers the detection zone by folding the paper. The injection zone is configured to inject a saliva sample acquired from a person thereon. The detection zone includes an array of chemical receptors configured to interact with the injected saliva penetrating into the detection zone. The processing unit is configured to perform a method of capturing a first image from the detection zone before injection of the saliva sample, capturing a second image from the detection zone after injection of the saliva sample, and detecting COVID-19 infection status of the person by analyzing color changes of the array of chemical receptors in the second image respective to the first image.

Abstract: According to a pad which is used for an immunochromatographic device for extracting a substance to be detected contained in a detection target in an analyte with nitrous acid and which contains an acid anhydride having vapor pressure at 25° C. of 5×10?2 Pa or less and solubility in water at 25° C. of 0.1 mg/L or more, the storage stability is improved; a substance to be detected contained in an analyte is detected with high sensitivity; and the complexity of production is reduced.

Abstract: A fluid sample testing apparatus has a fluid collector tube and a fluid collector in fluid communication with a sample holding container. The fluid collector is inserted into and penetrates the fluid collector tube and pressure is generated to release fluid from the fluid collector into the sample holding container, and air passes outside of the apparatus from the fluid collector tube via a vent path. The vent path is sealed with the fluid collector is fully inserted into the fluid collector tube. Indicator or test strips are optionally included in a stem of the fluid collector.

Abstract: A fluid sample testing apparatus has a housing with a test chamber and first and second fluid collector tubes and first and second fluid collectors in fluid communication with the test chamber. A sample holding container is in fluid communication with the second fluid collector tube. The first fluid collector is inserted into the first fluid collector tube and pressure is generated to release fluid from the first fluid collector into the test chamber, and air passes outside of the apparatus from the test chamber via an opening from the test chamber into the first fluid collector tube. The second fluid collector is inserted into the second fluid collector tube concurrently and pressure is generated to release fluid from the second fluid collector into the sample holding container, and air passes outside of the apparatus from the second fluid collector tube.

Abstract: A blood glucose level measuring chip exhibits excellent blood spreading ability and can maintain a reaction rate of blood with a reagent, even where the blood has a high hematocrit value (Ht). The blood glucose level measuring chip includes a blood glucose level measuring reagent including a supply port through which blood is supplied, a flow path having the supply port formed at one end of the flow path, and a blood glucose level measuring reagent containing an aromatic hydrocarbon having at least one sulfonic acid group disposed on an inner wall defining the flow path, wherein a ratio A/B is 3.7 mmol/L or more to 184.8 mmol/L when A (mmol) represents the total molar amount of aromatic hydrocarbons contained in the blood glucose level measuring reagent, and B (L) represents a volume of a region in which the blood glucose level measuring reagent and the blood are dissolved.

Abstract: A microfluidic diagnostic device comprises a base and at least one switch coupled to a portion of the base, the switch comprising a flap that is pivotable with respect to the base from a first position spaced away from the base a first distance to a second position where the flap is spaced away from the base a second distance. Both the base and the switch comprise one or more channels that permit passive transportation of an aqueous solution. The switch may be formed by bending or deforming a strip to cause the flap to be in the first position when there is less than a predetermined amount of fluid within the channel of switch. When a predetermined amount of fluid is in the channel of the switch, the flap pivots to the second position, which may be achieved through power from gravity, capillarity, and/or inherent elastic energy.

Abstract: A microfluidic valve may include a first portion of a liquid conduit to contain a gas, a second portion of a liquid conduit to contain a liquid, and a constriction between the first portion and the second portion and across which a capillary meniscus is to form between the gas and the liquid. The microfluidic valve may further include a drop jetting device within the second portion to open the valve by breaking the capillary meniscus across the constriction.

Abstract: A testing assembly for lateral flow assay comprising a liquid sample receiving unit arranged on a support structure defining a plane and configured to receive a liquid sample via the liquid sample receiving interface, at least one testing strip having, in a planar state, a testing strip center line length (L) in a longitudinal direction, a testing strip width in a width direction and a testing strip thickness, and comprising a capillary wick that includes a test portion that comprises a reacting material configured to react in a predetermined manner to a pre-specified analyte, wherein the width direction of the testing strip extends at an angle smaller than 90° with respect to a normal of the plane, and wherein the testing strip is curved, resulting in an effective extension being shorter than the testing strip center line length in the planar state.

Abstract: The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

Abstract: A liquid evaluation system can include a cartridge including a channel configured to pull a liquid into the channel by capillary action. The cartridge can include a first plate and a second plate located in close proximity to the first plate. An internal facing surface of each plate can include a corresponding region forming the channel. Each of the regions can have an affinity for the liquid. The close proximity of the plates and the regions having an affinity for the liquid cause the liquid to be pulled into the channel by capillary action. The cartridge can include one or more additional attributes and/or the system can include one or more additional components for performing the evaluation.

Abstract: In an example implementation, a reagent storage system for a microfluidic device includes a microfluidic chamber formed in a microfluidic device. A blister pack to store a reagent includes an electrically conductive membrane barrier adjacent to the chamber. A thinned region is formed in the membrane barrier, and a conductive trace is to supply electric current to heat and melt the thinned region. Melting the thinned region is to cause the membrane barrier to open and release the reagent into the chamber.

Abstract: A device enables a user to detect biomarkers, and includes an element that defines a multiplicity of microfluidic channels that communicate between an inlet duct and an outlet duct, the inlet duct communicating with an inlet port into which a user can introduce a drop of body fluid; the outlet duct communicating with an outlet port. A resilient bladder is connected to the outlet port to provide suction. Each microfluidic channel defines a reaction chamber containing a biomarker-sensitive reagent which provides a color or a change of color in the presence of a biomarker, there being a multiplicity of different biomarker-sensitive reagents, one such biomarker-sensitive reagent being provided in each of the multiplicity of different microfluidic channels. At least part of the element is transparent so the color within the reaction chamber can be seen. The device includes a cover with magnifying lenses above the reaction chambers. The device may be used in conjunction with a smart phone.