Patents Examined by Springer: David B.
  • Process for producing non-ionic radiographic contrast media utilizing N-allylation
    Patent number: 5191119
    Abstract: Methods are provided for substituting aromatic carboxylic acids and derivatives thereof and amino substituted aromatic carboxylic acids and derivatives thereof, by forming imides and imide-amides, respectively, by acylation with aliphatic carboxylic acids, substituting at least one nitrogen atom under mild basic conditions with an aliphatic compound having as alkylating agent a displaceable functionality and removing undesired acyl groups, as appropriate.
    Type: Grant
    Filed: July 5, 1990
    Date of Patent: March 2, 1993
    Assignee: Cook Imaging Corp.
    Inventors: Milos Sovak, Ramachandran Ranganathan