Patents Examined by Stanley S. Friedman
  • Method of inhibiting interleukin-1 release
    Patent number: 5034412
    Abstract: Methods useful for inhibiting the release of interleukin-1 and for alleviating interleukin-1 mediated conditions, such as IL-1-mediated inflammation, comprising administration of an effective amount of a pharmaceutically acceptable antioxidant compound such as disulfiram, tetrakis [3-(2,6-di-tert-butyl-4-hydroxyphenyl)propionyloxy methyl]methane or 2,4-di-isobutyl-6-(N,N-dimethylaminomethyl)-phenol.
    Type: Grant
    Filed: December 19, 1990
    Date of Patent: July 23, 1991
    Assignee: Merrell Dow Pharmacueticals Inc.
    Inventors: George Ku, Niall Doherty