Patents Examined by Stephan Lu
  • Process for the separation of proteins using a CA++ containing eluant
    Patent number: 6180757
    Abstract: The invention concerns a process of chromatographically separating glycosylated proteins from non-glycosylated proteins by subjecting a solution comprising glycosylated and non-glycosylated proteins to chromatography using a Ca++ containing eluant. By using this process a fraction comprising non-glycosylated proteins substantially free from glycosylated proteins is obtained. The process may be applied to the separation of proteins used in the medical industry, such as insulin.
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: January 30, 2001
    Assignee: Novo Nordisk A/S
    Inventor: Are Bogsnes