Patents Examined by Stephanie Ztonmer
  • Systematic evolution of ligands by exponential enrichment: chemi-SELEX
    Patent number: 5998142
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Grant
    Filed: August 21, 1997
    Date of Patent: December 7, 1999
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen