Abstract: A suture applying device comprises a shaft having a nose piece attached at its distal end. The shaft and the nose piece are separated by a transition region, and a needle entry lumen in the shaft permits a flexible needle to be introduced in the distal direction. The needle is able to cross the transition region and penetrate tissue held therein and enter into a return lumen in the nose piece. The return lumen is U-shaped and acts to bend the flexible needle as it is advanced. In this way, the needle passes from the nose piece through the transition region in a proximal direction, and is able to pass through tissue within the transition region generally on the opposite side of a tissue puncture from the first suture passage. The needle then exits from the device, permitting the suture attached to the needle to be drawn fully through the device. The suture may then be tied in order to close and seal the tissue penetration.

Abstract: A laparoscopic suturing device includes a suturing needle and a driver for manipulating the needle. The suturing needle features a helically-wound front-end portion with a needle point at its proximal end for penetrating tissue and a rear-end portion connected to the driver. The slender design of the suturing device is ideally suited for minimally-invasive surgery.

Abstract: An automatic biopsy instrument includes a cannula 13 provided over a stylet 11. The stylet 11 directs the cannula 13 to a biopsy site. The instrument urges the cannula 13 past the stylet 11 in order to collect a tissue sample. The stylet 11 initially remains stationary, then travels in the direction of travel of cannula 13 in order to assist firstly in collecting a sample and secondly to assist in severing the tissue sample from the surrounding mass.

Abstract: A gasket is made of a composite comprising hydrogen-added derivative (component a) of a styrenebutadiene block copolymer, a plasticizer (component b), and a polyethylene resin having a density of 0.940 g/cm.sup.3 or more (component c). A medical device includes a cylindrical body and a gasket capable of moving in close contact with the inner surface of the cylindrical body. The gasket of the medical device is the same of the aforesaid type of the gasket.