Patents Examined by Stephen Huang
  • Patent number: 6390977
    Abstract: Systems are methods described for calculating, in real-time, various oxygenation parameters including total oxygen transport, mixed venous blood oxygen tension and mixed venous blood oxyhemoglobin saturation in a patient. The system preferably uses a computer, an arterial pressure line and a blood chemistry monitor to assist a physician in accurately determining when to give a patient a blood transfusion or otherwise alter the clinical management of that patient.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: May 21, 2002
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Glenn Rhoades
  • Patent number: 5997483
    Abstract: Disposable air tubes having tracking information disposed thereon or disclosed. Spirometers for reading the tracking information on the disposable air tubes are also disclosed. The tracking information automatically ensures that air tubes are not re-used among different patients. The tracking information thus reduces or eliminates cross-contamination between patients and increases the accuracy of spirometry readings by reducing condensation buildup within the disposable air tubes.
    Type: Grant
    Filed: September 17, 1997
    Date of Patent: December 7, 1999
    Assignee: Desert Moon Development Limited Partnership
    Inventor: Michael O. Johnson
  • Patent number: 5919187
    Abstract: A thrombus is generated in an aneurysm, arteriovenous malformation or fistula by means of a catheter having an insulated heating coil coupled to an insulated delivery wire. In one embodiment, two delivery wires are coupled to heating coils to provide a closed circuit. The heating coils may be in the form of a double helix or a single helix in combination with a straight heating coil. The heating coils are permanently connected to the delivery wires. Alternatively, a single insulated heating coil may be attached to a single insulated delivery wire with a uninsulated coil attached to the tip of the insulated heating coil. The electrical circuit is then made through the heating coil and non-insulated electrode coil into the vascular system and to a body electrode. A catheter may also be used for heating blood within the vascular system which is directly flowed into a tumoral mass for the purposes of thermal treatment of cancer.
    Type: Grant
    Filed: September 15, 1995
    Date of Patent: July 6, 1999
    Assignee: The Regents of the University of California
    Inventors: Guido Guglielmi, Cheng Ji
  • Patent number: 5884626
    Abstract: An apparatus and method are provided for analyzing information relating to the physiological and psychological conditions of a driver. Psychological conditions such as comfortableness or degree of alertness are estimated on the basis of physical data such as fluctuation in brain waves. This apparatus comprises a first neural network having a pre-processed 1/f fluctuation signal for brain waves as an input and for estimating a degree of alertness of the driver, and a second neural network receiving the estimated degree of alertness and the pre-processed 1/f fluctuation signal, for estimating and outputting driving comfortableness. By employing a neural network, which has a mapping ability as well as flexible adaptability even for non-linear data, based on the learning function, more accurate estimation of mental conditions can be achieved in comparison with conventional statistical analysis.
    Type: Grant
    Filed: August 31, 1995
    Date of Patent: March 23, 1999
    Assignees: Toyota Jidosha Kabushiki Kaisha, Director-General of Agency of Industrial Science and Technology
    Inventors: Yukio Kuroda, Tomoyuki Yoshida
  • Patent number: 5868746
    Abstract: A biocompatible osteosynthesis plate operable for being enhanced in a substantially secured relation to a plurality of adjacent bone portions is provided. The biocompatible osteosynthesis plate includes an elongated section having a top face and a bottom face, at least one fastener opening disposed between the top face and the bottom face, and means disposed upon elongated section to permit the formation of additional fastener openings therethrough during a surgical procedure. The osteosynthesis plate is in a first configuration at a first thermochemical state and is operable to be converted to a second thermochemical state so that it may be deformed prior to fixation. The osteosynthesis plate may further include means disposed upon the elongated section for enhancing structural rigidity, which may be provided as one or more raised surfaces, or rails, disposed upon the top face of the osteosynthesis plate.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: February 9, 1999
    Assignee: Biomet, Inc.
    Inventors: David Ralph Sarver, Barry Lynn Eppley, Keith Raymond D'Alessio, William Stanley Pietrzak, Thomas Wendell Sander
  • Patent number: 5868135
    Abstract: A system is provided for interactively assisting a patient. The system includes a speech synthesizer and recognition unit coupled to a programmed computer. The computer can keep track of a medication and diagnostic testing schedule. The system also includes diagnostic testing equipment coupled to the computer along with medication dispensing equipment. In accordance with a predetermined schedule, the system verbally communicates with the patient, prompts the patient through the various steps necessary to carry out the diagnostic testing and further prompts patient at appropriate times for taking medication. The medication is also provided in combination with the verbal prompts. The system also provides access to a telecommunications link in response to verbal requests of the patient and in one embodiment can move in a limited area adjacent the patient.
    Type: Grant
    Filed: August 5, 1996
    Date of Patent: February 9, 1999
    Assignee: Healthtech Service Corporation
    Inventors: Stephen B. Kaufman, Shelly Hyland, Michael A. Lesczynski, Calvin L. Bryant
  • Patent number: 5861021
    Abstract: A method of applying microwave energy to cardiac tissue uses a catheter adapted for insertion into a cardiac chamber and which includes a microwave antenna, a cooling lumen structure, and an inflatable cooling balloon. Necrosing levels of microwave energy are delivered from the microwave antenna to diseased cardiac tissue spaced from the catheter. Tissues immediately surrounding the catheter are cooled and microwave energy emitted by the antenna is selectively absorbed by the cooling lumen structure surrounding the antenna. The cooling balloon of the catheter is positioned adjacent the antenna and partially surrounds the cooling lumen structure on one side of the catheter to provide additional cooling capability and additional microwave energy absorption on the side of the catheter opposite the diseased cardiac tissue to prevent unwanted heating of blood within the cardiac chamber.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: January 19, 1999
    Inventors: Scott P. Thome, Eric N. Rudie, Mitchell Dann, Teruo T. Hirose
  • Patent number: 5853364
    Abstract: A method and apparatus for reducing the effects of noise on a system for measuring physiological parameters, such as, for example, a pulse oximeter. The method and apparatus of the invention take into account the physical limitations on various physiological parameters being monitored when weighting and averaging a series of measurements. Varying weights are assigned different measurements, measurements are rejected, and the averaging period is adjusted according to the reliability of the measurements. Similarly, calculated values derived from analyzing the measurements are also assigned varying weights and averaged over adjustable periods. More specifically, a general class of filters such as, for example, Kalman filters, is employed in processing the measurements and calculated values. The filters use mathematical models which describe how the physiological parameters change in time, and how these parameters relate to measurement in a noisy environment.
    Type: Grant
    Filed: June 7, 1996
    Date of Patent: December 29, 1998
    Assignee: Nellcor Puritan Bennett, Inc.
    Inventors: Clark R. Baker, Jr., Thomas J. Yorkey
  • Patent number: 5842978
    Abstract: A supplemental emergency reviewing apparatus and method includes the operative steps of connecting a medical monitoring system to a patient and monitoring a selected function of the patient to provide a data output signal for producing alphanumeric data about the selected function and an alarm output signal in response to the selected function reaching an alarm condition, aiming a CCTV camera at the patient and recording an image thereof to provide a video output signal for producing a video picture of the patient while the selected function is being monitored, receiving and combining in a video interface device the data output signal and video output signal to provide a combined video and data output signal for producing the video record superimposed with the alphanumeric data, receiving and indexing in a VCR device the combined video and data output signal and alarm output signal to provide an indexed combined video and data output signal for producing the video record with superimposed data which can be in
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: December 1, 1998
    Inventor: Itchak Levy
  • Patent number: 5843144
    Abstract: A method for treating an individual with diseased prostatic tissue, such as benign prostatic hyperplasia, includes inserting a catheter into a urethra to position a microwave antenna located within the catheter adjacent a prostatic region of the urethra. A microwave antenna is then driven within a power range for applying microwave energy substantially continuously to prostatic tissue to heat the prostatic tissue surrounding the microwave antenna at a temperature and for a time period sufficient to cause necrosis of the prostatic tissue.
    Type: Grant
    Filed: June 26, 1995
    Date of Patent: December 1, 1998
    Assignee: Urologix, Inc.
    Inventors: Eric N. Rudie, Mitchell Dann, John M. Reid, Bruce H. Neilson, James V. Kauphusman, James E. Burgett, Stanley E. Kluge, Steven W. Norsted
  • Patent number: 5837005
    Abstract: A disposable thermal pad includes a substantially planar laminate structure having a first side and a second side and a plurality of heat generating cells embedded between the first and the second sides. The plurality of heat generating cells each are spaced apart and fixedly attached to the laminate structure. The laminate structure provides oxygen permeability to each of the plurality of heat generating cells. Oxygen permeability is achieved entirely on the first side of the laminate structure. The disposable thermal pad is releasably attachable to an inside portion of a user's clothing. The disposable thermal pad is releasably attachable on its first side of the laminate structure so that the second side of the thermal pad may be placed directly against a user's body.
    Type: Grant
    Filed: March 18, 1997
    Date of Patent: November 17, 1998
    Assignee: The Procter & Gamble Company
    Inventors: L. John Viltro, William R. Ouellette, Leane K. Davis
  • Patent number: 5830139
    Abstract: A tonometer system for measuring intraocular pressure by accurately providing a predetermined amount of applanation to the cornea and detecting the amount of force required to achieve the predetermined amount of applanation. The system is also capable of measuring intraocular pressure by indenting the cornea using a predetermined force applied using an indenting element and detecting the distance the indenting element moves into the cornea when the predetermined force is applied, the distance being inversely proportional to intraocular pressure. Also provided is a method of using the tonometer system to measure hydrodynamic characteristics of the eye, especially outflow facility. The tonometer system includes a contact device for placement in contact with the cornea and an actuation apparatus for actuating the contact device so that a portion thereof projects inwardly against the cornea to provide a predetermined amount of applanation.
    Type: Grant
    Filed: September 4, 1996
    Date of Patent: November 3, 1998
    Inventor: Marcio M. Abreu
  • Patent number: 5827272
    Abstract: An electrode catheter (2) includes a handle (4) to which a catheter shaft (6) is mounted. The catheter shaft has a distal end (10) carrying plurality of electrodes (12). Dual purpose wires (18) extend from an electrical connector (14) on the handle, through separate axial lumens (16) in the catheter shaft and to the electrodes. The dual purpose wires are physically secured at their distal and proximal ends to the distal end of the catheter shaft and to the handle, respectively, so that rotation of the handle causes a rotational torque to be transmitted through the dual purpose wires to the distal end of the catheter shaft. Each dual purpose wire has an electrical resistance of no greater than about 0.80 ohms per centimeter and a torsional stiffness of at least about 0.25 to 1.0 inch-ounce (17654 to 70616 dyne-cm) for each 110 cm length of catheter shaft when the proximal end of the catheter shaft is rotated 3 turns. This construction provides a simply constructed, low cost torquing electrode catheter.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: October 27, 1998
    Assignee: Medtronic CardioRhythm
    Inventors: Peter M. Breining, Scott H. West
  • Patent number: 5827183
    Abstract: A method for measuring the concentration of a chemical present in a blood stream of a mammalian subject is disclosed. The method involves contacting the subject's skin with a sensor assembly comprised of an ionically conducting material which contacts the skin, a working electrode which is in contact with the ionically conducting material which electrode has a catalytic surface and a mask having an opening therein. The mask is positioned between the skin and the working electrode. When the electrode is activated, chemical is transported through the skin and the ionically conductive material. The mask is positioned so that it blocks the flow into the catalytic surface except for flow which is substantially axially to the catalytic surface. Electrical signal generated at the working electrode is monitored over a period of time and correlated with a concentration of chemical present in the blood stream of the mammalian subject.
    Type: Grant
    Filed: October 29, 1997
    Date of Patent: October 27, 1998
    Assignee: Cygnus, Inc.
    Inventors: Ronald T. Kurnik, Janet Tamada, Michael Tierney
  • Patent number: 5817030
    Abstract: A plurality of locally sensitive, far-field immune sensors are mounted in mutually spaced relation on the exterior of the body of a subject to detect electrical signals associated with voluntary skeletal muscle activity in the immediate physical vicinity of the sensors. The detected signals are used to determine which, if any, of a predetermined series of voluntary skeletal muscle maneuvers is performed by the subject. A signal bearing a predetermined relationship to the maneuver is then transmitted to a device to be controlled based on which maneuver the subject has performed. Also disclosed are a novel sensor and a method of making same.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: October 6, 1998
    Assignee: University of Miami
    Inventors: Peter P. Tarjan, Sergio Jose Bonilla, Monica Kaufer-Braverman, Leonard L. Rasquinha
  • Patent number: 5817149
    Abstract: A therapeutic pad for heating or cooling has a liquid absorbent to prevent liquid leakage in the event the sealed envelope of the pad is ruptured. The method of forming the pad includes vacuuming the thermoplastic envelope prior to sealing. The pad can be used alone or with a comforter to provide warmth or to remove heat from the body of the user.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: October 6, 1998
    Assignee: Vesture Corporation
    Inventor: Bryon C. Owens
  • Patent number: 5813993
    Abstract: A drowsiness detection system constructed according to the invention provides improved performance by preserving and analyzing newly discovered information contained in rhythmic signal components above 30 Hz which the prior art has universally ignored or discarded as "noise." In the first and second embodiments of the invention, one or more analog EEG signals are collected from a subject, appropriately filtered, converted into digital form, and subjected to frequency analysis. Selected signal components from the frequencies above 30 Hz (such as the frequency range 80-420 Hz), which have a high correlation with subject drowsiness, are isolated, and their amplitude, energy, or power contribution to the EEG signal is used to produce a continuous output measure reflecting the subject's alertness or drowsiness. The output measure may be compared with a threshold to provide an indication of whether the subject is excessively drowsy.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: September 29, 1998
    Assignee: Consolidated Research of Richmond, Inc.
    Inventors: Richard Frederic Kaplan, Kenneth Alan Loparo
  • Patent number: 5813989
    Abstract: A driving mental condition detecting apparatus for detecting a deterioration state of driving mental conditions such as sleepiness, fatigue, and impatience occurring in a driver on the basis of physiological data detected from the driver and road travel data of a vehicle derived from a navigation system, thereby generating an alarm.
    Type: Grant
    Filed: November 15, 1995
    Date of Patent: September 29, 1998
    Assignee: Pioneer Electronic Corporation
    Inventors: Satoshi Saitoh, Mitsuo Yasushi, Kazuhiro Akiyama, Masatoshi Yanagidaira
  • Patent number: 5807245
    Abstract: A measurement system including a first unit that obtains a first measurement value associated with a first time indication and a second measurement value associated with a second time indication and a second unit that comprises a processor and receives values asynchronously from the first unit, wherein the processor synchronizes the first and second measurement values using the first and second time indications.
    Type: Grant
    Filed: November 27, 1995
    Date of Patent: September 15, 1998
    Assignee: Astra Aktiebolag
    Inventors: Sten Aldestam, Goran Marnfeldt, Johan Waldeck
  • Patent number: 5807393
    Abstract: A locking mechanism for ensuring proper sequential usage of a surgical instrument is provided for an instrument utilizing a tissue treating energy, particularly a tissue heating energy, such as, for example, electrosurgical, ultrasonic, thermal, laser, infrared light, or other heating energies. One embodiment includes a cutting element to be used after heat treatment of tissue is completed to a desired degree. The instrument of the preferred embodiment includes a feedback monitor arranged to provide a signal indicating completion of tissue treatment. One embodiment includes an electro-mechanical locking mechanism responsive to the tissue treatment complete feedback signal and arranged to unlock when tissue treatment is complete.
    Type: Grant
    Filed: May 8, 1995
    Date of Patent: September 15, 1998
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Warren P. Williamson, IV, David C. Yates