Patents Examined by Stuart L. Hendricks
  • Pt(IV) complexes as anti-tumor agents
    Patent number: 5244919
    Abstract: A Pt(IV) complex of the formula ##STR1## wherein A and A' are NH.sub.3 or an amino group; R and R.sup.1 are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally.
    Type: Grant
    Filed: July 1, 1991
    Date of Patent: September 14, 1993
    Assignee: Johnson Matthey, Inc.
    Inventors: Michael J. Abrams, Christen M. Giandomenico, Barry A. Murrer, Jean F. Vollano
  • Preparation of ortho substituted diphenylphosphides
    Patent number: 5118854
    Abstract: Alkali metal di(2-alkoxyphenyl)phosphide is produced in good yield by reaction of alkali metal and the corresponding tri(2-alkoxyphenyl)-phosphine in liquid ammonia.
    Type: Grant
    Filed: October 7, 1991
    Date of Patent: June 2, 1992
    Assignee: Shell Oil Company
    Inventors: Johannes A. Van Doorn, Nicolaas Meijboom, Richard L. Wife