Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
Type:
Grant
Filed:
March 26, 2004
Date of Patent:
April 22, 2008
Assignee:
Arius Research Inc.
Inventors:
David S. F. Young, Susan E. Hahn, Helen P. Findlay, Luis A. G. da Cruz