Patents Examined by Suzanne M. Naokes
  • Patent number: 10557115
    Abstract: Provided are a novel medium for expressing glycoproteins by culturing cells and a method for producing glycoproteins by culturing cells in the medium. Further provided are a medium comprising uridine and N-acetyl-D-mannosamine for the use of expression of a glycoprotein by culturing cells and a method for producing glycoproteins by culturing cells in for medium.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: February 11, 2020
    Assignee: JCR Pharmaceuticals Co., Ltd.
    Inventors: Miroslav Matev, Kenichi Takahashi, Shinji Kakimoto, Ayaka Kotani
  • Patent number: 8017750
    Abstract: The present invention provides a venene haemocoagulase gene and its expression for the functional protein. The haemocoagulase gene of the present invention has a nucleotide sequence shown by the sequence list SEQ ID NO: 1 or the mutated nucleotide sequence formed by replacement, depletion, or addition of one or more nucleotide based on the said nucleotide sequence with an equivalent function. The said haemocoagulase has amino acid sequence shown by SEQ ID NO: 2. Haemocoagulase of the present invention has an obvious hemostatic effect, a broad effective dose range, safe and reliable application, which creates good conditions for the development of genetic engineering products of recombinant haemocoagulase in the future.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: September 13, 2011
    Assignee: Konruns Pharmaceutical Co., Ltd
    Inventor: Xijuan Wang
  • Patent number: 7993893
    Abstract: The present invention provides a venene haemocoagulase gene and its expression for the functional protein. The haemocoagulase gene of the present invention has a nucleotide sequence shown by the sequence list SEQ ID NO: 1 or the mutated nucleotide sequence formed by replacement, depletion, or addition of one or more nucleotide based on the said nucleotide sequence with an equivalent function. The said haemocoagulase has amino acid sequence shown by SEQ ID NO: 2. Haemocoagulase of the present invention has an obvious hemostatic effect, a broad effective dose range, safe and reliable application, which creates good conditions for the development of genetic engineering products of recombinant haemocoagulase in the future.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: August 9, 2011
    Assignee: Konruns Pharmaceutical Co., Ltd
    Inventor: Xijuan Wang
  • Patent number: 7504491
    Abstract: An object of the present invention is to provide a chromoprotein derived from Cnidopus japonicus. The present invention provides a chromoprotein derived from Cnidopus japonicus having the following properties: (1) the absorption maximum wavelength is 610 nm, and fluorescence is not emitted; (2) the molar absorption coefficient is 66,700 at 610 nm; and (3) the pH sensitivity of light-absorbing property is stable at between pH 4 and pH 10.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: March 17, 2009
    Assignees: Riken, Medical and Biological Laboratories Co., Ltd.
    Inventors: Atsushi Miyawaki, Satoshi Karasawa