Patents Examined by T. A. Trembley
  • Patent number: 5223405
    Abstract: A sample of a biological tissue and/or fluid, particularly plant sap, may be taken by placing biological tissue such as a leaf between a layer which is adsorbent for detectable biological material (for example nitrocellulose) and a substrate and applying pressure to urge the adsorbent layer and the substrate towards each other, thereby causing detectable biological material to be adsorbed on the adsorbent layer. The invention thus provides a convenient method of obtaining, securing and transporting small samples of plant sap or other fluid or tissue to the laboratory for such purposes as analysis for plant viruses and other organisms.
    Type: Grant
    Filed: September 5, 1990
    Date of Patent: June 29, 1993
    Assignee: The Secretary of State for Scotland
    Inventors: Peter J. Howell, D. Gavin Rose, David H. Mitchell
  • Patent number: 5223217
    Abstract: A method is provided wherein a plant for filling vials and similar containers comprising syringes and filling nozzles as well as nozzles for nitrogen injection is submitted to one or more washings and to a steam sterilization. Sterile nitrogen is then fed to the plant at slight overpressure to maintain the plant in sterile condition until it is used again. The device to carry out the method comprises a line for nitrogen injection, of the type normally used for nitrogen injection into vials, provided with an offtake connected by means of valves to the lines for water and steam feeding in order to alternatively feed water, steam or nitrogen to the syringes and filling nozzles, and steam or nitrogen to the injection nozzles and to the sterile filter for nitrogen filtration. The device is preferably automatically operated.
    Type: Grant
    Filed: January 29, 1991
    Date of Patent: June 29, 1993
    Assignee: Capsulit S.p.A.
    Inventor: Denis Frizziero
  • Patent number: 5217695
    Abstract: This invention provides a multipurpose volumetric chemical reaction system which operates at constant pressure and volume, and has electronic automation means for calculating kinetic parameters and a concentration-time plot from the system data output.The automated system is adapted to conduct and monitor either gas-consuming or gas-generating reactions. Gas input or gas venting is accomplished in timed constant volume pulses.
    Type: Grant
    Filed: September 11, 1991
    Date of Patent: June 8, 1993
    Assignees: Philip Morris Incorporated, Philip Morris Products Inc.
    Inventors: Robert L. Augustine, Setrak K. Tanielyan
  • Patent number: 5217692
    Abstract: A gas sensor arrangement has at least a first sensor element which is primarily sensitive towards oxidizable gases and generates a corresponding measuring signal and an electric control and evaluation unit, wherein the measuring signal generated by the first sensor element is evaluated. In order to avoid inaccuracies when in addition to the oxidizable gases at the same time also reducible gases are present, the gas sensor arrangement is provided with at least one second sensor element, which is primarily sensitive to reducible gases and generates a corresponding measuring signal, which is fed to the control and evaluation unit for evaluation.
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: June 8, 1993
    Assignee: E.T.R. Elektronik Technologie Rump GmbH
    Inventors: Hanns Rump, Claus-Dieter Kohl
  • Patent number: 5217688
    Abstract: A safe, practical, and less costly method for disposing of infectious personal care waste, as well as pathological waste and equipment which can be configured for large municipal type use employing continuous process techniques, or for smaller, batch type, stand-alone processors for individual sites such as hospitals.
    Type: Grant
    Filed: January 23, 1992
    Date of Patent: June 8, 1993
    Inventor: Wolf A. Von Lersner
  • Patent number: 5215921
    Abstract: A water manifold and air supply system for use with a multi-compartment rotating drum apparatus for the fermentation of natural organic material which provides for selective injection of air and predetermined amounts of water into compartments of the drum during its rotation which system includes an air supply conduit concentrically aligned with the rotational axis of the drum, a first water-conduit section fixedly secured to the rotating drum, a second water-conduit section concentric with the rotational axis of the drum residing within the air supply conduit and connected to the first section through a water-tight seal, the two water-conduit sections and air supply conduit being respectively connected to stationary water-supply and air-supply means by swivel joints.
    Type: Grant
    Filed: October 28, 1991
    Date of Patent: June 1, 1993
    Assignee: Bedminster Bioconversion Corporation
    Inventor: Larry J. Finn
  • Patent number: 5213775
    Abstract: The device comprises an external fixed hollow casing (20) provided with a concave surface (21) of revolution about a central axis A and with two apertures (22') and (22") for passage of the objects, each aperture communicating with a respective environment; within the casing (20) there is provided a structure (10) rotatable about the axis A and in sealed engagement with the concave surface (21); the structure (10) comprises at least one blind chamber (11) for containing the objects; the structure (10) rotates to carry the objects which it receives from one aperture (22') to the other aperture (22"); in whatever angular position the structure (10) lies, it closes communication between the two apertures (22') and (22"); the device is applicable in particular to sterilization or pasteurization plants and represents an improvement to known device, and in particular achieves very high productivity.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: May 25, 1993
    Assignee: Dall'Argine & Ghiretti S.r.l.
    Inventor: Ermes Ghiretti
  • Patent number: 5212090
    Abstract: There is disclosed a cover structure for use with fermentation and the like containers. The cover structure includes a lower cover having a plurality of layers of strips of material covering the container, with the strip layers angularly oriented to each other. Spaces can be formed between strips, and in one embodiment the second strips are connected along their sides at spaced intervals to form the spaces. This can provide gaps in the sheet covering the container, allowing gases to pass through. Additionally, spacers may be positioned on the lower cover with a further membrane extending thereover. The spacers create passages for collection of gases escaping through the lower cover. Floating gas collectors may also be provided for collection of gases for further treatment. The cover can provide insulation, to a variable degree.
    Type: Grant
    Filed: January 31, 1991
    Date of Patent: May 18, 1993
    Inventors: Robert Landine, Albert Cocci, Graham J. Brown
  • Patent number: 5210021
    Abstract: A simple chemotactic apparatus and method wherein surface tension is used to hold cell suspensions, chemotactic factors, and control fluids in place on membrane filters. In some embodiments, chemotaxis factors and controls are placed on one side of a membrane filter, and cell suspensions are placed on the other. Gravitational flow is limited by the effect of surface tension on the fluids. In some of the preferred embodiments, grids, sheets, or occluding materials are used to further limit the gravitational fluid flow.
    Type: Grant
    Filed: March 20, 1991
    Date of Patent: May 11, 1993
    Assignee: Neuro Probe, Inc.
    Inventor: Richard H. Goodwin, Jr.
  • Patent number: 5206145
    Abstract: An apparatus is provided for measuring the concentration of a substance in a sample solution. The apparatus comprises first electrode means, second electrode means and an enzyme channel between the first and second electrode means. The enzyme channel contains an enzyme for catalyzing a reaction of the substance whose concentration is to be measured. In use, a known volume of the sample solution is presented to the first electrode means in a test solution including an excess of a mediator, one of reduction or oxidation of the mediator being coupled to the reaction of the substance. The first electrode means is arranged to ensure that the mediator is respectively completely oxidized or reduced, and also to remove any interferent species. The test solution is then passed through the enzyme channel so as to permit reaction of all of the substance present in the solution, whereby a quantity of the mediator is respectively reduced or oxidized.
    Type: Grant
    Filed: August 23, 1991
    Date of Patent: April 27, 1993
    Assignee: Thorn EMI plc
    Inventor: Alan F. Cattell
  • Patent number: 5204262
    Abstract: A probe for continuously measuring the precise concentration of liquid ethanol in a fermentation broth over the range of feasible fermentation temperatures. The probe includes a thermal sensor, a gas permeable membrane leading to a vapor channel, an ethanol vapor sensor in a vapor sensing chamber, and a microcomputer. The microcomputer is loaded with a first set of data defining the initial parameters of the fermentation broth and a set of data defining the ethanol diffusion rate through the gas permeable membrane as a function of the temperature of such fermentation broth. Inlet and outlet connection and tubular interconnections are provided for leading a flushing gas through the vapor channel, past the ethanol vapor sensor and out a vent outlet. Electrical lines leading from the thermal sensor to the microcomputer provide an input signal which is proportional to the temperature of the fermentation broth.
    Type: Grant
    Filed: March 1, 1991
    Date of Patent: April 20, 1993
    Inventors: Anton G. Meiering, Ronald E. Subden
  • Patent number: 5202261
    Abstract: A conductive sensor and its use in a diagnostic assay are disclosed. The miniaturized conductive sensor, utilizing a conducting polymer, is used in a diagnostic device to determine the presence or concentration of a predetermined analyte in a liquid test sample, wherein the predetermined analyte, like glucose, is assayed by an oxidase interaction. The interaction between the oxidase and a small amount of the predetermined analyte in the test sample generates, either directly or indirectly, a dopant compound in a reaction zone of the conductive sensor. The dopant compound then migrates to the detection zone of the conductive sensor of the diagnostic device to oxidize the conducting polymer and convert the conducting polymer from an insulating form to a conducting form. The resulting increase in conductivity of the conducting polymer is measured, then the conductivity increase is correlated to the concentration of the predetermined analyte in the test sample.
    Type: Grant
    Filed: November 18, 1991
    Date of Patent: April 13, 1993
    Assignee: Miles Inc.
    Inventors: Matthew K. Musho, J. Oakey Noell, Pius H. Tse
  • Patent number: 5198192
    Abstract: A urine detection device is disposed to a urine receiving surface of a toilet stool in which urine, diluting water and reagent are mixed by vertically moving a piston in the cylinder of the detection device, the reaction between them is detected by an electrode and the ingredient in urine is detected. Liquid in the cylinder is stirred by a stirring device to blown air into the reagent reservoir, by which oxygen is dissolved in the reagent. Cleaning liquid is sprayed from the nozzle to the electrode for flushing. An opening is disposed to a supporting wall of the toilet stool, through which the cylinder is detached or attached. The electrode is disposed such that its rear end is directed to the opening and detached or attached through the opening.
    Type: Grant
    Filed: May 31, 1989
    Date of Patent: March 30, 1993
    Assignee: Inax Corporation
    Inventors: Shiro Saito, Ryuichi Kawamoto, Mineharu Kondo, Shigeru Sakakibara
  • Patent number: 5196341
    Abstract: Apparatus for detecting micro-organisms comprises a sample container releasably received in a container-mounting member which comprises a spillage containment vessel. The sample container has secured to its base a socket member which nests with the inner surface of the spillage containment vessel. Spillage detection means comprises a pair of electrical probes in the base of the vessel.
    Type: Grant
    Filed: September 1, 1989
    Date of Patent: March 23, 1993
    Assignee: CMB Foodcan plc
    Inventors: Martin R. Ackland, Roderick M. De'Ath
  • Patent number: 5194231
    Abstract: A packing for a vessel to contact fluid therein wherein the packing comprises a plurality of insert units, each insert unit comprising a plurality of transversely extending elements disposed longitudinally along the insert unit and angularly thereabout wherein a portion of each transverse element lies in close proximity to a first individual conceptual surface characterized in that the insert units are disposed in side-by-side relationship in a regular manner and the cross-sectional area between adjacent individual conceptual surfaces of adjacent insert units at least at one position longitudinally of the plurality of insert units is no greater than the maximum cross-sectional area within an individual conceptual surface of an insert unit between two adjacent transversely extending elements thereof at any cross-section longitudinally of the plurality of units.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: March 16, 1993
    Assignee: Citten Fluid Technology Limited
    Inventors: Martin J. Gough, Stephen R. M. Ellis, John V. Rogers
  • Patent number: 5190878
    Abstract: The apparatus uses a holding device (2) which has a support ring (3) and a fixed ring (4). A cell substrate (1) is held between support ring (3) and fixed ring (4). The fixed ring (4) has a thickness less than the cylindrical height (3') of the support ring (3) so that only the support ring abuts against the surface of the culture vessel. Since fixing ring (4) does not abut against a surface, there is no pressure on the cell substrate (1). The holding device (2) is held inside the apparatus with space on both the apical and basal sides. Inflow ports (13) and outflow ports (14) are provided for both apical space and basal space to allow for introduction of cell treatment medium.
    Type: Grant
    Filed: December 14, 1990
    Date of Patent: March 2, 1993
    Inventor: Minuth Wilhelm
  • Patent number: 5187097
    Abstract: The disclosure is directed to a large composting system as well as to a new composting method for the automatic production of compost. A mobile layer rearranging unit includes a conveyor system which is changeable with respect to length can be remote-controlled so that the influx of rotting matter is optimized according to throughput and rotting time and the rot loss is compensated for by repeatedly restoring the complete rot height. The required space requirement is less than before. Any mechanical intervention has a loosening effect, particularly in that the working device comprises upwardly working digging and conveyor wheels. All important parameters for the compost ripening can be monitored via free programming as well as by control by the system maintenance personnel.
    Type: Grant
    Filed: March 23, 1990
    Date of Patent: February 16, 1993
    Assignee: Buehler AG
    Inventors: Heinrich Weber, Falko Lehrmann, Hermann Hofer, Werner Vogel, Peter Mueller
  • Patent number: 5187072
    Abstract: A method and apparatus for testing for the presence of selected microorganisms can be used in the field or in the laboratory. A sample to be tested is mixed with a culture medium for promoting growth of the selected microorganisms. A test device of a semi-permeable material is inverted in the culture medium, and the test device is held to a vertical position. The microorganisms create a biofilm within the test device, and the test device subsequently retains gas generated by the microorganisms. The gas lowers the density of the test device, causing the test device to float. The floating is taken as an indication of the presence of the selected microorganisms; and, by measuring the time required for the test device to float, the size of the population of the selected microorganisms can be determined.
    Type: Grant
    Filed: March 19, 1991
    Date of Patent: February 16, 1993
    Inventors: D. Roy Cullimore, George W. Alford, Abimbola T. Abiola, Jeff Reihl, Karim Naqvi
  • Patent number: 5187096
    Abstract: An apparatus and method for monitoring cell-substrate impedance comprises upper and lower substrates each containing strips of metal foil which cross to form well areas. Holes in the upper substrate expose an insulation layer between the upper and lower substrates. Smaller holes in the insulation layer expose the conductive material of the lower substrate. Cylindrical well walls are positioned around each of the holes in the upper substrate and define a cell medium containing well which is exposed to an annular area of conductive foil on the upper substrate, and a small area of conducive foil on the lower substrate. The areas of foil form large and small electrodes which are positioned in an array of wells which can be used to monitor the impedance of various cell cultures under various conditions. A switching device applies currents to the well electrodes and a monitoring device measures the impedance between the electrodes in each well. In this way, cell spreading and motility can be measured.
    Type: Grant
    Filed: August 8, 1991
    Date of Patent: February 16, 1993
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ivar Giaever, Charles R. Keese
  • Patent number: 5185261
    Abstract: A composting apparatus is provided comprising two similar units arranged side-by-side each provided with a wire mesh basket structure as its lowermost extremity. The units are installed in a hole in the ground, with the wire baskets underneath and allowing below-ground communication between the composting contents therein. Each unit has an inclined top wall with a radiation transmissive lid therein, air ducts extending upwardly and allowing air ingress into the units through an adjustable opening, and a common exhaust duct with an exhaust fan. A deodorizing filter is provided in the common exhaust duct. The units are insulated to enhance heat retention.
    Type: Grant
    Filed: July 8, 1991
    Date of Patent: February 9, 1993
    Inventor: Jack E. Warrington