Abstract: This invention generally relates to the detection, determination, and quantitation of certain ions and small molecules involving the quenching of a fluorescent label attached to a macromolecule, often due to fluorescence energy transfer to a colored inhibitor or certain metal ions bound to the macromolecule.
Type:
Grant
Filed:
October 25, 1996
Date of Patent:
September 14, 1999
Inventors:
Richard B. Thompson, Marcia W. Patchan, Zhengfang Ge