Abstract: A poorly soluble medicament is incorporated into particles of a crosslinked polymer which is swellable in water but insoluble in water, and the product obtained is brought into contact with a solvent able to swell the polymer. The product obtained by this treatment, and after being dried under vacuum, has a medicament dissolving rate which is considerably higher than that of the pure medicament.
Abstract: A process for micronizing a slightly-soluble drug characterized by subjecting a mixture of said drug and a sugar or sugar alcohol to high-speed stirring comminution or impact comminution in order to produce a micronized drug having an average diameter of less than about 2-3 mm. Also provided is a pharmaceutical formulation which comprises the micronized drug.
Abstract: An aqueous gel based on hyaluronic acid and on deoxyribonucleic acid usable in cosmetics, and a method of preparation.The invention relates to an aqueous gel formed by a homogeneous mix of:a) an alkaline salt or an ammonium salt of hyaluronic acid in the form of an aqueous gel;b) a mineral or organic salt of high molecular weight deoxyribonucleic acid in the form of an aqueous gel;c) at least one hydrophilic polymer having the property of forming aqueous film-forming gels.Application to the preparation of masks in cosmetics.
Abstract: A process for preparing a water-insoluble PVP-iodine product which comprises intimately mixing water-insoluble PVP, about 10 to 20% by weight of iodine powder and about 0.05 to 1% by weight of isopropanol, heating the reaction mixture at a mixing temperature of about 30.degree.-60.degree. C. for about 0.5 to 6 hours, and heating the mixture at a reaction temperature of about 75.degree. to 98.degree. C. for about 10-24 hours, thereupon forming a stable, uniform, free-flowing powder having an available iodine content of about 9-13% and an iodide content of about 4-6%.
Abstract: Polyelectrolyte membrane capsules are composed of a semi-permeable membrane and an active material enclosed by it, the membrane being formed of a biocompatible, non-toxic polyacid and a polybase; the polybase is composed of repeating monomer units of the formula (I) ##STR1## in which R.sup.1 and R.sup.2 have the indicated meanings.
Abstract: Chloroprene or a mixture of chloroprene and a comonomer is polymerized by emulsion polymerization in the presence of an alkali metal or ammonium salt of an aliphatic substituted benzoic acid or a non-ionic polyoxyethylene ether or ester surfactant. The resulting chloroprene polymer is admixed with a solvent, a metal oxide and a thermosettable resin, e.g., an alkylphenol-formaldehyde resin to yield a non-phasing adhesive composition.